8tbs A 2.35 BS01 FBP A 1 T475 T476 T477 S480 W525 R532 G557 R559 G561 S562 G563 Y564 T565 T387 T388 T389 S392 W437 R444 G469 R471 G473 S474 G475 Y476 T477 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 QQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIKGSQVLVTVDPAFNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKQVENGGVLGSRKGVNLPLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs A 2.35 BS02 MN A 1 E315 D339 E227 D251 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 602 QQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIKGSQVLVTVDPAFNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKQVENGGVLGSRKGVNLPLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs A 2.35 BS03 PYR A 1 K313 E315 A336 G338 D339 T371 K225 E227 A248 G250 D251 T283 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 604 QQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIKGSQVLVTVDPAFNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKQVENGGVLGSRKGVNLPLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs A 2.35 BS04 HVI B 1 F69 Q436 L437 F13 Q348 L349 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 QQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIKGSQVLVTVDPAFNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKQVENGGVLGSRKGVNLPLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs B 2.35 BS01 HVI B 1 F69 D397 Q436 L437 E440 F15 D340 Q379 L380 E383 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 FFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs B 2.35 BS02 FBP B 1 L474 T475 T476 T477 S480 W525 R532 G557 R559 G561 S562 G563 Y564 T565 L417 T418 T419 T420 S423 W468 R475 G500 R502 G504 S505 G506 Y507 T508 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 602 FFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs B 2.35 BS03 MN B 1 E315 D339 E258 D282 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 603 FFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs B 2.35 BS04 PYR B 1 E315 A336 G338 D339 T371 E258 A279 G281 D282 T314 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 605 FFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs C 2.35 BS01 FBP C 1 L474 T475 T476 T477 S480 W525 R532 T556 G557 G561 S562 G563 L413 T414 T415 T416 S419 W464 R471 T495 G496 G500 S501 G502 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 LGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIPESEVELVKGSQVLVTVDPAGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs C 2.35 BS02 MN C 1 E315 D339 E254 D278 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 602 LGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIPESEVELVKGSQVLVTVDPAGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs C 2.35 BS03 PYR C 1 K313 E315 A336 G338 D339 T371 K252 E254 A275 G277 D278 T310 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 604 LGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIPESEVELVKGSQVLVTVDPAGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs C 2.35 BS04 HVI D 1 F69 Q436 L437 F19 Q375 L376 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 LGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIPESEVELVKGSQVLVTVDPAGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs D 2.35 BS01 HVI D 1 F69 D397 Q436 L437 E440 F13 D307 Q346 L347 E350 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 QQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILANTVWVDYPNIVRVVPVGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs D 2.35 BS02 FBP D 1 L474 T475 T476 T477 S480 W525 R532 G557 R559 P560 G561 S562 G563 Y564 T565 L384 T385 T386 T387 S390 W435 R442 G467 R469 P470 G471 S472 G473 Y474 T475 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 602 QQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILANTVWVDYPNIVRVVPVGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs D 2.35 BS03 MN D 1 E315 D339 E225 D249 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 603 QQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILANTVWVDYPNIVRVVPVGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs D 2.35 BS04 PYR D 1 A336 G338 D339 T371 A246 G248 D249 T281 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 604 QQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILANTVWVDYPNIVRVVPVGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs E 2.35 BS01 FBP E 1 L474 T475 T476 T477 S480 R532 G557 R559 P560 G561 S562 Y564 L416 T417 T418 T419 S422 R474 G499 R501 P502 G503 S504 Y506 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs E 2.35 BS02 MN E 1 K313 E315 D339 K255 E257 D281 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 602 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs E 2.35 BS03 PYR E 1 K313 A336 G338 D339 T371 K255 A278 G280 D281 T313 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 604 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs E 2.35 BS04 HVI F 1 F69 Q436 L437 F20 Q378 L379 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs F 2.35 BS01 HVI F 1 F69 D397 Q436 L437 F16 D343 Q382 L383 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 AFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs F 2.35 BS02 FBP F 1 L474 T475 T476 T477 S480 W525 R532 G557 R559 G561 S562 Y564 T565 L420 T421 T422 T423 S426 W471 R478 G503 R505 G507 S508 Y510 T511 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 602 AFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs F 2.35 BS03 MN F 1 E315 D339 E261 D285 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 603 AFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs F 2.35 BS04 PYR F 1 E315 D339 E261 D285 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 605 AFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs G 2.35 BS01 FBP G 1 L474 T475 T476 T477 S480 R532 G557 R559 P560 G561 S562 G563 Y564 T565 L410 T411 T412 T413 S416 R468 G493 R495 P496 G497 S498 G499 Y500 T501 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIGPESEVELVKGSQVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs G 2.35 BS02 MN G 1 E315 D339 E251 D275 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 602 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIGPESEVELVKGSQVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs G 2.35 BS03 PYR G 1 K313 E315 A336 G338 D339 T371 K249 E251 A272 G274 D275 T307 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 604 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIGPESEVELVKGSQVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs G 2.35 BS04 HVI H 1 F69 Q436 L437 F20 Q372 L373 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIGPESEVELVKGSQVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 8tbs H 2.35 BS01 HVI H 1 F69 D397 Q436 L437 F16 D342 Q381 L382 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 601 AFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs H 2.35 BS02 FBP H 1 L474 T475 T476 T477 S480 W525 R532 G557 R559 G561 S562 G563 Y564 T565 L419 T420 T421 T422 S425 W470 R477 G502 R504 G506 S507 G508 Y509 T510 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 602 AFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs H 2.35 BS03 MN H 1 K313 E315 D339 K258 E260 D284 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 603 AFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS 8tbs H 2.35 BS04 PYR H 1 E161 E315 D339 E108 E260 D284 2.7.1.40 0000287,0001666,0003824,0004743,0005515,0005524,0005737,0005829,0006096,0007584,0009749,0010038,0016301,0016310,0030955,0032869,0033198,0042866,0046872,0048029,0051591,0070062,0071872 P30613 38109501 604 AFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS