8a22 Aa 2.91 BS01 rna A3 0 K75 R77 T78 K109 S111 R113 R118 I119 K282 A283 G284 R287 K288 R292 P293 V295 A299 K300 N301 N303 D304 K19 R21 T22 K53 S55 R57 R62 I63 K226 A227 G228 R231 K232 R236 P237 V239 A243 K244 N245 N247 D248 0003723,0003735,0005840,0006412,0015934,0016740 36253367 1 ~ 210 KYTYKFKQARAVPGLVYWKPRTPGLRHKISIDYDFLGVYTGAPHKDLSAAVPKLSGRNNHGRITARHRGGGMKKVLRQVDYSREKVDGIPGVVERVEKDPNRSGFLALVKYQPEGQLPIFKYHLAPAEIKAGDVLLSGDGAPVQAGSTLPLRSIPLGTPIHNLELTPGKGGQLARAANVSAVIQSKQLENAIVKLPSGEIRLINLDCRATVGRVSNHLQRMINYGKAGERRKLGWRPSVRGIAKNPNDHPHGGRTNGGRPSCTPWGVYCKGQRTRRRNNYTNKFIITRKGGQPIRKFAEAKKLKAR 8a22 AA 2.91 BS01 rna A7 0 R21 G33 N41 N44 T45 L49 M52 F54 R60 H61 R1 G13 N21 N24 T25 L29 M32 F34 R40 H41 0003735,0005840,0006412 36253367 1 ~ 576 RLLVKMVSLAKTGYFYVTTKNPRNTPWKLKLMKFDPVVGRHVLFEESKLK 8a22 Aa 2.91 BS02 rna A7 0 K57 T59 Y60 P76 R82 H83 G112 N114 N115 H116 T120 R124 Y137 Q228 L229 R231 A232 A233 N234 L251 S253 E255 R257 R276 N279 Y280 A283 P293 R296 G297 I298 N312 G313 G314 S317 W321 C325 K326 G327 Q328 T330 R331 R332 R333 T337 R344 G346 Q348 K357 K358 K1 T3 Y4 P20 R26 H27 G56 N58 N59 H60 T64 R68 Y81 Q172 L173 R175 A176 A177 N178 L195 S197 E199 R201 R220 N223 Y224 A227 P237 R240 G241 I242 N256 G257 G258 S261 W265 C269 K270 G271 Q272 T274 R275 R276 R277 T281 R288 G290 Q292 K301 K302 0003723,0003735,0005840,0006412,0015934,0016740 36253367 1 ~ 576 KYTYKFKQARAVPGLVYWKPRTPGLRHKISIDYDFLGVYTGAPHKDLSAAVPKLSGRNNHGRITARHRGGGMKKVLRQVDYSREKVDGIPGVVERVEKDPNRSGFLALVKYQPEGQLPIFKYHLAPAEIKAGDVLLSGDGAPVQAGSTLPLRSIPLGTPIHNLELTPGKGGQLARAANVSAVIQSKQLENAIVKLPSGEIRLINLDCRATVGRVSNHLQRMINYGKAGERRKLGWRPSVRGIAKNPNDHPHGGRTNGGRPSCTPWGVYCKGQRTRRRNNYTNKFIITRKGGQPIRKFAEAKKLKAR 8a22 Aa 2.91 BS03 rna A8 0 G309 R310 T311 G253 R254 T255 0003723,0003735,0005840,0006412,0015934,0016740 36253367 1 ~ 350 KYTYKFKQARAVPGLVYWKPRTPGLRHKISIDYDFLGVYTGAPHKDLSAAVPKLSGRNNHGRITARHRGGGMKKVLRQVDYSREKVDGIPGVVERVEKDPNRSGFLALVKYQPEGQLPIFKYHLAPAEIKAGDVLLSGDGAPVQAGSTLPLRSIPLGTPIHNLELTPGKGGQLARAANVSAVIQSKQLENAIVKLPSGEIRLINLDCRATVGRVSNHLQRMINYGKAGERRKLGWRPSVRGIAKNPNDHPHGGRTNGGRPSCTPWGVYCKGQRTRRRNNYTNKFIITRKGGQPIRKFAEAKKLKAR 8a22 Aa 2.91 BS04 rna B3 0 K57 R276 K1 R220 0003723,0003735,0005840,0006412,0015934,0016740 36253367 13 ~ 391 KYTYKFKQARAVPGLVYWKPRTPGLRHKISIDYDFLGVYTGAPHKDLSAAVPKLSGRNNHGRITARHRGGGMKKVLRQVDYSREKVDGIPGVVERVEKDPNRSGFLALVKYQPEGQLPIFKYHLAPAEIKAGDVLLSGDGAPVQAGSTLPLRSIPLGTPIHNLELTPGKGGQLARAANVSAVIQSKQLENAIVKLPSGEIRLINLDCRATVGRVSNHLQRMINYGKAGERRKLGWRPSVRGIAKNPNDHPHGGRTNGGRPSCTPWGVYCKGQRTRRRNNYTNKFIITRKGGQPIRKFAEAKKLKAR 8a22 AB 2.91 BS01 rna A1 0 Y120 R127 H131 R136 R148 R149 K152 G153 R154 W155 Y7 R14 H18 R23 R35 R36 K39 G40 R41 W42 0003735,0005840,0006412 36253367 1 ~ 109 MKRGMTYQPSRKKRINKHGMEKRLGTEDGRLTILRRLEKGRWRLTVDMFR 8a22 Ab 2.91 BS01 rna A7 0 G98 Y99 R100 F263 G265 S278 H279 L283 H285 R286 T291 G293 Q295 G298 K299 G1 Y2 R3 F166 G168 S181 H182 L186 H188 R189 T194 G196 Q198 G201 K202 0003735,0005840,0006412 36253367 1 ~ 576 GYRPAKPVYPLPDSIASLVEDKIAELKKFGPTPEPALEPLPLTPDSVRVGCITVKAGMTHEWDEHGVMIPLTVLWIDECQVVGLKYFEKNGYYAVQLGAGCVKQHTVLPQIAGYYLKHDLPIKREMKEYQVSSPEALLPVGTHITAAHFVVGQQVDVTGYTTDKGFQGVMKRWGFKGMPASHGVSLSHRKPGATGGRQDPGKIWKEKKLPGHMGDEKRTQLGLELYKVDPKRNLLYVKGAVPGPRGASILVRDSNRMDYEERVALNLPYPTFIGSPDELPVLVRKSDKDPYLMYKKEIDYFPIKWK 8a22 AB 2.91 BS02 rna A3 0 M114 K115 R116 G117 T119 Q121 S123 K126 R127 K130 H131 M1 K2 R3 G4 T6 Q8 S10 K13 R14 K17 H18 0003735,0005840,0006412 36253367 1 ~ 210 MKRGMTYQPSRKKRINKHGMEKRLGTEDGRLTILRRLEKGRWRLTVDMFR 8a22 Ab 2.91 BS02 rna A8 0 Y99 M155 H157 P167 K186 Y189 K200 H202 L205 Q207 Y211 K214 E225 T259 R269 F272 G274 G280 S284 P288 A290 G293 R294 Q295 D296 I300 W301 K302 E303 K304 L306 H309 K314 R315 T316 Q317 L318 A337 V338 P339 R353 Y397 Y2 M58 H60 P70 K89 Y92 K103 H105 L108 Q110 Y114 K117 E128 T162 R172 F175 G177 G183 S187 P191 A193 G196 R197 Q198 D199 I203 W204 K205 E206 K207 L209 H212 K217 R218 T219 Q220 L221 A240 V241 P242 R256 Y300 0003735,0005840,0006412 36253367 1 ~ 350 GYRPAKPVYPLPDSIASLVEDKIAELKKFGPTPEPALEPLPLTPDSVRVGCITVKAGMTHEWDEHGVMIPLTVLWIDECQVVGLKYFEKNGYYAVQLGAGCVKQHTVLPQIAGYYLKHDLPIKREMKEYQVSSPEALLPVGTHITAAHFVVGQQVDVTGYTTDKGFQGVMKRWGFKGMPASHGVSLSHRKPGATGGRQDPGKIWKEKKLPGHMGDEKRTQLGLELYKVDPKRNLLYVKGAVPGPRGASILVRDSNRMDYEERVALNLPYPTFIGSPDELPVLVRKSDKDPYLMYKKEIDYFPIKWK 8a22 AB 2.91 BS03 rna A7 0 M114 R116 M1 R3 0003735,0005840,0006412 36253367 1 ~ 576 MKRGMTYQPSRKKRINKHGMEKRLGTEDGRLTILRRLEKGRWRLTVDMFR 8a22 Ac 2.91 BS01 rna A1 0 R148 Q152 Q153 T155 H156 V164 S165 G166 R169 R186 R191 R101 Q105 Q106 T108 H109 V117 S118 G119 R122 R139 R144 0003735,0005840,0006412 36253367 1 ~ 109 VASYLARICPNTYVPPPFVATKKGFNGIGGRYDPSSPFPPDTGSSPLTLQYPFEVEYHKDREIPVCNVSDGSQVSTTTLNGKIFSDKVRLDILHTVVRYLRAKWQQGTHKTKDRSEVSGGGRKPRPQKGSGRSRQGSIRSPIWRGGGCTFPKIPRSHAFKLPRNVVRIGIRSALSAKANEGRLFVVDSFVRGVESYDQLKAGLAEVTKDAIGESLLLVDSGECGEDYSGVKLRRLLPKDSPRVEVLSYQDLTVYHMLKYHKLVVSEPAVRLIEQELTRPLRNPARAAFWQEREARIGAAVEDL 8a22 AC 2.91 BS01 rna A1 0 R73 N75 Q77 H79 K83 R8 N10 Q12 H14 K18 36253367 1 ~ 109 VFAEVKPRQNPQNHTHEKYKIIAPQPKYDWLVGRFIVDRNNVVWHRQANRNRNRHKKTAGALTRLKRWKPLHKAYAKKLLKLGFKRRFWTDPDPQMVPGFFDPSKYKPRERLNGKPNLRPDIGCPALRQSQRPLKKLPR 8a22 Ac 2.91 BS02 rna A2 0 R136 F197 P209 R210 N211 L327 R328 N329 P330 A331 R89 F150 P162 R163 N164 L280 R281 N282 P283 A284 0003735,0005840,0006412 36253367 1 ~ 81 VASYLARICPNTYVPPPFVATKKGFNGIGGRYDPSSPFPPDTGSSPLTLQYPFEVEYHKDREIPVCNVSDGSQVSTTTLNGKIFSDKVRLDILHTVVRYLRAKWQQGTHKTKDRSEVSGGGRKPRPQKGSGRSRQGSIRSPIWRGGGCTFPKIPRSHAFKLPRNVVRIGIRSALSAKANEGRLFVVDSFVRGVESYDQLKAGLAEVTKDAIGESLLLVDSGECGEDYSGVKLRRLLPKDSPRVEVLSYQDLTVYHMLKYHKLVVSEPAVRLIEQELTRPLRNPARAAFWQEREARIGAAVEDL 8a22 AC 2.91 BS02 rna A3 0 A88 P89 H137 K143 K146 Q194 S195 A23 P24 H72 K78 K81 Q129 S130 36253367 1 ~ 210 VFAEVKPRQNPQNHTHEKYKIIAPQPKYDWLVGRFIVDRNNVVWHRQANRNRNRHKKTAGALTRLKRWKPLHKAYAKKLLKLGFKRRFWTDPDPQMVPGFFDPSKYKPRERLNGKPNLRPDIGCPALRQSQRPLKKLPR 8a22 Ac 2.91 BS03 rna A3 0 R145 D160 R161 S162 R169 K170 Q174 R181 G183 F206 K207 R98 D113 R114 S115 R122 K123 Q127 R134 G136 F159 K160 0003735,0005840,0006412 36253367 1 ~ 210 VASYLARICPNTYVPPPFVATKKGFNGIGGRYDPSSPFPPDTGSSPLTLQYPFEVEYHKDREIPVCNVSDGSQVSTTTLNGKIFSDKVRLDILHTVVRYLRAKWQQGTHKTKDRSEVSGGGRKPRPQKGSGRSRQGSIRSPIWRGGGCTFPKIPRSHAFKLPRNVVRIGIRSALSAKANEGRLFVVDSFVRGVESYDQLKAGLAEVTKDAIGESLLLVDSGECGEDYSGVKLRRLLPKDSPRVEVLSYQDLTVYHMLKYHKLVVSEPAVRLIEQELTRPLRNPARAAFWQEREARIGAAVEDL 8a22 AC 2.91 BS03 rna A4 0 K142 K146 K77 K81 36253367 1 ~ 73 VFAEVKPRQNPQNHTHEKYKIIAPQPKYDWLVGRFIVDRNNVVWHRQANRNRNRHKKTAGALTRLKRWKPLHKAYAKKLLKLGFKRRFWTDPDPQMVPGFFDPSKYKPRERLNGKPNLRPDIGCPALRQSQRPLKKLPR 8a22 Ac 2.91 BS04 rna A6 0 F85 H141 R148 R172 G178 R179 S180 I189 R191 K199 R202 Y301 F38 H94 R101 R125 G131 R132 S133 I142 R144 K152 R155 Y254 0003735,0005840,0006412 36253367 1 ~ 132 VASYLARICPNTYVPPPFVATKKGFNGIGGRYDPSSPFPPDTGSSPLTLQYPFEVEYHKDREIPVCNVSDGSQVSTTTLNGKIFSDKVRLDILHTVVRYLRAKWQQGTHKTKDRSEVSGGGRKPRPQKGSGRSRQGSIRSPIWRGGGCTFPKIPRSHAFKLPRNVVRIGIRSALSAKANEGRLFVVDSFVRGVESYDQLKAGLAEVTKDAIGESLLLVDSGECGEDYSGVKLRRLLPKDSPRVEVLSYQDLTVYHMLKYHKLVVSEPAVRLIEQELTRPLRNPARAAFWQEREARIGAAVEDL 8a22 AC 2.91 BS04 rna A7 0 Q112 A113 N114 N116 R117 K121 L130 R132 G179 S195 Q196 R197 R204 Q47 A48 N49 N51 R52 K56 L65 R67 G114 S130 Q131 R132 R139 36253367 1 ~ 576 VFAEVKPRQNPQNHTHEKYKIIAPQPKYDWLVGRFIVDRNNVVWHRQANRNRNRHKKTAGALTRLKRWKPLHKAYAKKLLKLGFKRRFWTDPDPQMVPGFFDPSKYKPRERLNGKPNLRPDIGCPALRQSQRPLKKLPR 8a22 Ac 2.91 BS05 rna A7 0 K175 G176 K128 G129 0003735,0005840,0006412 36253367 1 ~ 576 VASYLARICPNTYVPPPFVATKKGFNGIGGRYDPSSPFPPDTGSSPLTLQYPFEVEYHKDREIPVCNVSDGSQVSTTTLNGKIFSDKVRLDILHTVVRYLRAKWQQGTHKTKDRSEVSGGGRKPRPQKGSGRSRQGSIRSPIWRGGGCTFPKIPRSHAFKLPRNVVRIGIRSALSAKANEGRLFVVDSFVRGVESYDQLKAGLAEVTKDAIGESLLLVDSGECGEDYSGVKLRRLLPKDSPRVEVLSYQDLTVYHMLKYHKLVVSEPAVRLIEQELTRPLRNPARAAFWQEREARIGAAVEDL 8a22 AC 2.91 BS05 rna A8 0 R117 R119 H120 R174 R176 L183 P185 R52 R54 H55 R109 R111 L118 P120 36253367 1 ~ 350 VFAEVKPRQNPQNHTHEKYKIIAPQPKYDWLVGRFIVDRNNVVWHRQANRNRNRHKKTAGALTRLKRWKPLHKAYAKKLLKLGFKRRFWTDPDPQMVPGFFDPSKYKPRERLNGKPNLRPDIGCPALRQSQRPLKKLPR 8a22 Ac 2.91 BS06 rna A8 0 Q174 K175 R181 Q127 K128 R134 0003735,0005840,0006412 36253367 1 ~ 350 VASYLARICPNTYVPPPFVATKKGFNGIGGRYDPSSPFPPDTGSSPLTLQYPFEVEYHKDREIPVCNVSDGSQVSTTTLNGKIFSDKVRLDILHTVVRYLRAKWQQGTHKTKDRSEVSGGGRKPRPQKGSGRSRQGSIRSPIWRGGGCTFPKIPRSHAFKLPRNVVRIGIRSALSAKANEGRLFVVDSFVRGVESYDQLKAGLAEVTKDAIGESLLLVDSGECGEDYSGVKLRRLLPKDSPRVEVLSYQDLTVYHMLKYHKLVVSEPAVRLIEQELTRPLRNPARAAFWQEREARIGAAVEDL 8a22 AD 2.91 BS01 rna A5 0 R26 H32 K49 F50 R52 R20 H26 K43 F44 R46 0003735,0005840,0006412 36253367 1 ~ 142 MKVRGKVKLFCDGCVRTIVRLAKEKHIVLVECSKNPRHKQRSKFAR 8a22 Ad 2.91 BS01 rna A9 0 Y54 T68 E71 H75 R213 Y14 T28 E31 H35 R173 36253367 51 ~ 129 SSLHLTSRYHHMFYNVLYREMMLKAPKTKVEQGPHLESITLTIKTTDTRLDKDIVDKWELLLFSLALEHITGEPAAFLPPPNRHVANKSAGVTVTLKGEKMFNFLEKLVYTILPNQTGFEGVPQPKTLVPGPDGVVKRVVDFGVTNLLLYPDFEEHFGVFEPIRSMQVRMMIRSDSDESCNMLVSGLLVPQLE 8a22 AD 2.91 BS02 rna A8 0 M7 K8 G11 K12 K14 N41 R43 K49 M1 K2 G5 K6 K8 N35 R37 K43 0003735,0005840,0006412 36253367 1 ~ 350 MKVRGKVKLFCDGCVRTIVRLAKEKHIVLVECSKNPRHKQRSKFAR 8a22 AD 2.91 BS03 ZN AD 1 C38 H44 C32 H38 0003735,0005840,0006412 36253367 101 MKVRGKVKLFCDGCVRTIVRLAKEKHIVLVECSKNPRHKQRSKFAR 8a22 Ae 2.91 BS01 rna A8 0 Y1 I3 P4 K8 K11 W156 F162 R164 F189 T190 F237 R254 Y1 I3 P4 K8 K11 W148 F154 R156 F177 T178 F225 R242 0003735,0005840,0006412,0019843 36253367 1 ~ 350 YKIPDKIKWPKTPYSKICGRPAPEAYPIFEILKNADKPDVWQRSLIRFPEGVEARVDEETRVLHLEGKAGSVSINMKNLDPTGLLAYSFEQNSLVMLSPSKEKLNAFVQEIQKSVRGASQGYLVGLTVKGVGYRMEPVEDIPAKYLSWSRPVYFDRTTPPAYPFKKPAKAVLLKIGFTDPAVFMLPPTIKAFFLKPTLMYLYGLNIDELRKTAMDIRALRKPNVFTGNGIALLDETVRIKQR 8a22 AE 2.91 BS01 rna A9 0 K101 K104 V108 H109 N112 H113 R120 T123 E124 A127 K31 K34 V38 H39 N42 H43 R50 T53 E54 A57 36253367 51 ~ 129 EGNTRLQKVVSFFVPEVEKKEEEEKLATQYKRWKVAQVHAWNHDIAVKHRLQTEAIASLPQRLKEQALKPDYSPIPLNRKLLFHTPPESYRD 8a22 AF 2.91 BS01 rna A6 0 K46 R59 K47 R60 0003735,0005762 36253367 1 ~ 132 VRSKVYQIFLKNAPTREEVLKKVYEHAQQQQGLRKGWQVKAASWVKKIHVDRGDVKVGLRGRDGQFHVIDDLLPKYVVPDLKNFELKPYVALS 8a22 AF 2.91 BS02 rna A7 0 K45 H48 R51 Q64 F65 K46 H49 R52 Q65 F66 0003735,0005762 36253367 1 ~ 576 VRSKVYQIFLKNAPTREEVLKKVYEHAQQQQGLRKGWQVKAASWVKKIHVDRGDVKVGLRGRDGQFHVIDDLLPKYVVPDLKNFELKPYVALS 8a22 AG 2.91 BS01 rna A6 0 G27 S28 R58 R79 N80 G20 S21 R51 R72 N73 0003735,0032543 36253367 1 ~ 132 AKYGTHMLESLVFKYCDIGGSSRGMRLFLKDYMDPFKQTNPQLRIEEVQNRRRHPMLVALYRNGQCKPVCVRNLSPEEIAKHIFWLRNSHGRDDDYKVPRSHKVVRNESIQGTWAPQGPTL 8a22 Ah 2.91 BS01 rna A2 0 P85 Y86 N151 V152 T153 P62 Y63 N128 V129 T130 0003735,0005840,0006412 36253367 1 ~ 81 MQPILNHTFPRNVQLRALKELKNIDLNGLRMRFVDAKGVGLGSLAMKVATILQGKDKPTYSPYRENGDVVVVVNAAHIYLSQDKWETMKYWWHTGYAGGARELTAKQMWEKDPCQIIVRAVNGMLPKNVTRIQRMEKLKVFAEDEHPFKDFPLTPLVIEQRKGFGWAPPEGFKPLNPERFDLRRRI 8a22 Ah 2.91 BS02 rna A4 0 M69 K78 M147 R184 M46 K55 M124 R161 0003735,0005840,0006412 36253367 1 ~ 73 MQPILNHTFPRNVQLRALKELKNIDLNGLRMRFVDAKGVGLGSLAMKVATILQGKDKPTYSPYRENGDVVVVVNAAHIYLSQDKWETMKYWWHTGYAGGARELTAKQMWEKDPCQIIVRAVNGMLPKNVTRIQRMEKLKVFAEDEHPFKDFPLTPLVIEQRKGFGWAPPEGFKPLNPERFDLRRRI 8a22 Ah 2.91 BS03 rna A5 0 G65 S104 Q105 K107 W114 H116 M147 K189 I213 G42 S81 Q82 K84 W91 H93 M124 K162 I186 0003735,0005840,0006412 36253367 1 ~ 142 MQPILNHTFPRNVQLRALKELKNIDLNGLRMRFVDAKGVGLGSLAMKVATILQGKDKPTYSPYRENGDVVVVVNAAHIYLSQDKWETMKYWWHTGYAGGARELTAKQMWEKDPCQIIVRAVNGMLPKNVTRIQRMEKLKVFAEDEHPFKDFPLTPLVIEQRKGFGWAPPEGFKPLNPERFDLRRRI 8a22 Ah 2.91 BS04 rna A8 0 N29 R34 K42 T117 Y119 K134 N6 R11 K19 T94 Y96 K111 0003735,0005840,0006412 36253367 1 ~ 350 MQPILNHTFPRNVQLRALKELKNIDLNGLRMRFVDAKGVGLGSLAMKVATILQGKDKPTYSPYRENGDVVVVVNAAHIYLSQDKWETMKYWWHTGYAGGARELTAKQMWEKDPCQIIVRAVNGMLPKNVTRIQRMEKLKVFAEDEHPFKDFPLTPLVIEQRKGFGWAPPEGFKPLNPERFDLRRRI 8a22 AI 2.91 BS01 rna A4 0 V9 K12 T14 G16 W19 R34 S35 V1 K4 T6 G8 W11 R26 S27 36253367 1 ~ 73 VVFKTTGGKAWNPPGGLKPLTNTQKRSRKENLQILLRNLSVLKLAAENQPEVTVNLFSPLKFMH 8a22 Ai 2.91 BS01 rna A7 0 M3 P5 Y7 F9 M57 K66 F67 M1 P3 Y5 F7 M55 K64 F65 0003735,0005840,0006412 36253367 1 ~ 576 MLPNYSFLKVVDNSGAKLVKIIGFYGHPGKAVGVGEVVKVAIKEAKGEKVSAGEMKKAVIVEQKFPVFRPNGSHFRHLRNSCVLLSEKGQPLGNKVRALLTYEFIKPRWSKLRTITTKKLF 8a22 AI 2.91 BS02 rna A5 0 K33 R34 K25 R26 36253367 1 ~ 142 VVFKTTGGKAWNPPGGLKPLTNTQKRSRKENLQILLRNLSVLKLAAENQPEVTVNLFSPLKFMH 8a22 Ai 2.91 BS02 rna A8 0 M3 Y7 F26 Y27 H29 K41 M1 Y5 F24 Y25 H27 K39 0003735,0005840,0006412 36253367 1 ~ 350 MLPNYSFLKVVDNSGAKLVKIIGFYGHPGKAVGVGEVVKVAIKEAKGEKVSAGEMKKAVIVEQKFPVFRPNGSHFRHLRNSCVLLSEKGQPLGNKVRALLTYEFIKPRWSKLRTITTKKLF 8a22 AI 2.91 BS03 rna A9 0 F11 L28 R36 F3 L20 R28 36253367 51 ~ 129 VVFKTTGGKAWNPPGGLKPLTNTQKRSRKENLQILLRNLSVLKLAAENQPEVTVNLFSPLKFMH 8a22 Aj 2.91 BS01 rna A2 0 N13 E23 R25 K40 S82 K83 S112 Y120 N122 V123 F166 N14 E24 R26 K41 S83 K84 S113 Y121 N123 V124 F167 0003735,0006412,0015934 36253367 1 ~ 81 NPNYFVHLGNLRPNPGATQQRIREGRGLSSRRGVSCGMGFKGQKARGRSLHMLYDGGQLGLVKFPVTRQIPSYEVLYNQLGVSKLVEFIQLGLLDHTKTITMKELLNAGCVSSLKYGVLLYGNVSLSFPINIEVTACDDRARRSIEAAGGKVTRVYYTKDGLEGLLFPKRFTDKNLPLPRPAVAWHPKFDGKFDAVGQIPPVYEAV 8a22 AJ 2.91 BS01 rna A7 0 R70 R78 K104 K120 K121 R124 R56 R64 K90 K106 K107 R110 36253367 1 ~ 576 AHYLQRFGEAALPPLVPFSEALKIREEAYKLGQVWPFEHVVPGVPKAPNATAYLERKKQKEEKRTKRAKEINDALAKMPQLIADYKAARKIDWAEVSIIDKLTLSKKQIREKYVKRRLMKQN 8a22 Aj 2.91 BS02 rna A3 0 T17 Q18 R20 G24 R25 G26 S28 G32 V33 C35 Q42 K43 R45 R47 L49 M51 Y53 D54 G55 Q57 T18 Q19 R21 G25 R26 G27 S29 G33 V34 C36 Q43 K44 R46 R48 L50 M52 Y54 D55 G56 Q58 0003735,0006412,0015934 36253367 1 ~ 210 NPNYFVHLGNLRPNPGATQQRIREGRGLSSRRGVSCGMGFKGQKARGRSLHMLYDGGQLGLVKFPVTRQIPSYEVLYNQLGVSKLVEFIQLGLLDHTKTITMKELLNAGCVSSLKYGVLLYGNVSLSFPINIEVTACDDRARRSIEAAGGKVTRVYYTKDGLEGLLFPKRFTDKNLPLPRPAVAWHPKFDGKFDAVGQIPPVYEAV 8a22 Aj 2.91 BS03 rna A6 0 L10 Q18 Q19 R22 R30 S34 G36 L11 Q19 Q20 R23 R31 S35 G37 0003735,0006412,0015934 36253367 1 ~ 132 NPNYFVHLGNLRPNPGATQQRIREGRGLSSRRGVSCGMGFKGQKARGRSLHMLYDGGQLGLVKFPVTRQIPSYEVLYNQLGVSKLVEFIQLGLLDHTKTITMKELLNAGCVSSLKYGVLLYGNVSLSFPINIEVTACDDRARRSIEAAGGKVTRVYYTKDGLEGLLFPKRFTDKNLPLPRPAVAWHPKFDGKFDAVGQIPPVYEAV 8a22 Aj 2.91 BS04 rna A7 0 Q57 K62 F63 V65 Q58 K63 F64 V66 0003735,0006412,0015934 36253367 1 ~ 576 NPNYFVHLGNLRPNPGATQQRIREGRGLSSRRGVSCGMGFKGQKARGRSLHMLYDGGQLGLVKFPVTRQIPSYEVLYNQLGVSKLVEFIQLGLLDHTKTITMKELLNAGCVSSLKYGVLLYGNVSLSFPINIEVTACDDRARRSIEAAGGKVTRVYYTKDGLEGLLFPKRFTDKNLPLPRPAVAWHPKFDGKFDAVGQIPPVYEAV 8a22 Aj 2.91 BS05 rna A8 0 Q57 K62 R67 Q58 K63 R68 0003735,0006412,0015934 36253367 1 ~ 350 NPNYFVHLGNLRPNPGATQQRIREGRGLSSRRGVSCGMGFKGQKARGRSLHMLYDGGQLGLVKFPVTRQIPSYEVLYNQLGVSKLVEFIQLGLLDHTKTITMKELLNAGCVSSLKYGVLLYGNVSLSFPINIEVTACDDRARRSIEAAGGKVTRVYYTKDGLEGLLFPKRFTDKNLPLPRPAVAWHPKFDGKFDAVGQIPPVYEAV 8a22 Ak 2.91 BS01 rna A3 0 W106 V109 C110 W6 V9 C10 0003735,0005840,0006412,0019843 36253367 1 ~ 210 FRRRTWPAVCGSLHIWKKMPWRIDQAPPPMPDSKPLTRLRAKRYEGIKKVVMPNSTQLQFGLYGIRSMESARLKDNTLEAIRRTIRRKIKKTGRLWIMIRATVPMTKKPLGIRMGKGKGSIDHYVTPIRPGQILYEFDRISRPIALQALRAIQPKLPCRLGLVEWS 8a22 AK 2.91 BS01 rna A6 0 K21 A23 Q25 H30 Q31 Y34 K48 I49 F50 W64 R82 Y94 K21 A23 Q25 H30 Q31 Y34 K48 I49 F50 W64 R82 Y94 36253367 1 ~ 132 RPIMHKNWDWEFVVGAKAGRKPAIQRPKPHQWYYCNPKYSAEDPLPTKIFPPHAPPTAESLDDWAKFRKLCPKDPVEAKKFRKHFVRFLNQRNYDWRTAFERGLAKEVAVAKAAQRAEDETKRQEAWHAYRTAVFESAL 8a22 Ak 2.91 BS02 rna A4 0 R143 Y144 I147 R172 K218 R43 Y44 I47 R72 K118 0003735,0005840,0006412,0019843 36253367 1 ~ 73 FRRRTWPAVCGSLHIWKKMPWRIDQAPPPMPDSKPLTRLRAKRYEGIKKVVMPNSTQLQFGLYGIRSMESARLKDNTLEAIRRTIRRKIKKTGRLWIMIRATVPMTKKPLGIRMGKGKGSIDHYVTPIRPGQILYEFDRISRPIALQALRAIQPKLPCRLGLVEWS 8a22 AK 2.91 BS02 rna A7 0 A23 R26 K28 H30 R87 Q91 E101 A23 R26 K28 H30 R87 Q91 E101 36253367 1 ~ 576 RPIMHKNWDWEFVVGAKAGRKPAIQRPKPHQWYYCNPKYSAEDPLPTKIFPPHAPPTAESLDDWAKFRKLCPKDPVEAKKFRKHFVRFLNQRNYDWRTAFERGLAKEVAVAKAAQRAEDETKRQEAWHAYRTAVFESAL 8a22 Ak 2.91 BS03 rna A5 0 R250 R259 R150 R159 0003735,0005840,0006412,0019843 36253367 1 ~ 142 FRRRTWPAVCGSLHIWKKMPWRIDQAPPPMPDSKPLTRLRAKRYEGIKKVVMPNSTQLQFGLYGIRSMESARLKDNTLEAIRRTIRRKIKKTGRLWIMIRATVPMTKKPLGIRMGKGKGSIDHYVTPIRPGQILYEFDRISRPIALQALRAIQPKLPCRLGLVEWS 8a22 Ak 2.91 BS04 rna A7 0 R102 T105 A108 S112 H114 W116 P120 L139 K142 R213 M214 K216 G217 R2 T5 A8 S12 H14 W16 P20 L39 K42 R113 M114 K116 G117 0003735,0005840,0006412,0019843 36253367 1 ~ 576 FRRRTWPAVCGSLHIWKKMPWRIDQAPPPMPDSKPLTRLRAKRYEGIKKVVMPNSTQLQFGLYGIRSMESARLKDNTLEAIRRTIRRKIKKTGRLWIMIRATVPMTKKPLGIRMGKGKGSIDHYVTPIRPGQILYEFDRISRPIALQALRAIQPKLPCRLGLVEWS 8a22 Ak 2.91 BS05 rna A8 0 T177 G211 M214 K255 P257 T77 G111 M114 K155 P157 0003735,0005840,0006412,0019843 36253367 1 ~ 350 FRRRTWPAVCGSLHIWKKMPWRIDQAPPPMPDSKPLTRLRAKRYEGIKKVVMPNSTQLQFGLYGIRSMESARLKDNTLEAIRRTIRRKIKKTGRLWIMIRATVPMTKKPLGIRMGKGKGSIDHYVTPIRPGQILYEFDRISRPIALQALRAIQPKLPCRLGLVEWS 8a22 Ak 2.91 BS06 rna A9 0 F101 M119 D124 Q125 F1 M19 D24 Q25 0003735,0005840,0006412,0019843 36253367 51 ~ 129 FRRRTWPAVCGSLHIWKKMPWRIDQAPPPMPDSKPLTRLRAKRYEGIKKVVMPNSTQLQFGLYGIRSMESARLKDNTLEAIRRTIRRKIKKTGRLWIMIRATVPMTKKPLGIRMGKGKGSIDHYVTPIRPGQILYEFDRISRPIALQALRAIQPKLPCRLGLVEWS 8a22 AL 2.91 BS01 rna A3 0 S97 T98 E99 Y100 H103 L105 R106 K126 R135 E141 Y142 R184 M219 D220 R222 F226 T260 R263 S266 R295 F301 S302 L305 Q339 T340 V343 R369 S16 T17 E18 Y19 H22 L24 R25 K45 R54 E60 Y61 R103 M138 D139 R141 F145 T179 R182 S185 R214 F220 S221 L224 Q258 T259 V262 R288 36253367 1 ~ 210 NTGVPGPRPEVAQKLSTEYQGHILRMISLAESASELDEVLWSSKKHLRPVHIARSCLKLEYLRTKEKGREVSEPIKNLASELENYVELYSTKFTIGQVSQLVRGLSSIRRNIQPDLLLKLAAVVVADDGRQVQLANEMDCRDLFFGFFSQGFDNELFWKRLSESVLPRLPYFNADVVSTVLRVVSGLRFLHNTEFAHATMTALVPKVGDLSPARLADAFFSASLLDPTDVSGLNAKLEERFLREFTSFPIKDTVTMFQTVTVRRHSTPELAAQVAPLVAAQAHQLPVRHLRRALEGMVTAGWKDTAEIPLYAILAKQAARLVLTPVQLLRQLARIFANTGLKAGPGANQPLAPYFAALQRELEGRLAELDEQVTDDFAESFKKVGIAEGARVQI 8a22 Al 2.91 BS01 rna A6 0 L24 N27 Q31 K35 I38 R39 R75 G109 L24 N27 Q31 K35 I38 R39 R75 G109 0003735,0005840,0006412 36253367 1 ~ 132 TVKRFLRPGGWNRLNRPVKERLALIKNMATQLVEKERIRTTLSKAKNLQRYGDKLITLGKAGTRESWLKANDIVRTDRELHKLFTTLALRYKDRQGGYVRLIRAGFRRGDAAPVAIVELVDREGELRQARPAVTPVPKFSVMRWVKQQLDPKFISEPAPLLPPLVRDYLKEQN 8a22 Al 2.91 BS02 rna A7 0 L6 R7 N12 R13 L14 R16 S43 D110 L6 R7 N12 R13 L14 R16 S43 D110 0003735,0005840,0006412 36253367 1 ~ 576 TVKRFLRPGGWNRLNRPVKERLALIKNMATQLVEKERIRTTLSKAKNLQRYGDKLITLGKAGTRESWLKANDIVRTDRELHKLFTTLALRYKDRQGGYVRLIRAGFRRGDAAPVAIVELVDREGELRQARPAVTPVPKFSVMRWVKQQLDPKFISEPAPLLPPLVRDYLKEQN 8a22 Al 2.91 BS03 rna A8 0 T1 V2 K3 R4 L6 P8 W11 N12 V18 R21 L22 K46 R50 K54 T57 R94 G96 G97 R100 R127 R130 T134 K146 F153 T1 V2 K3 R4 L6 P8 W11 N12 V18 R21 L22 K46 R50 K54 T57 R94 G96 G97 R100 R127 R130 T134 K146 F153 0003735,0005840,0006412 36253367 1 ~ 350 TVKRFLRPGGWNRLNRPVKERLALIKNMATQLVEKERIRTTLSKAKNLQRYGDKLITLGKAGTRESWLKANDIVRTDRELHKLFTTLALRYKDRQGGYVRLIRAGFRRGDAAPVAIVELVDREGELRQARPAVTPVPKFSVMRWVKQQLDPKFISEPAPLLPPLVRDYLKEQN 8a22 AM 2.91 BS01 rna A3 0 T4 G5 V6 R10 P11 E12 V13 Q15 T5 G6 V7 R11 P12 E13 V14 Q16 36253367 1 ~ 210 TIFNTGVPGPRPEVAQKLSTEYQGHILRMISLAESASELDEVLWSSKKHLRPVHIARSCLKLEYLRTKEKGREVSEPIKNLASELENYVELYSTKFTIGQVSQLVRGLSSIRRNIQPDLLLKLAAVVVADDGRQVQLANEMDCRDLFFGFFSQGFDNELFWKRLSESVLPRLPYFNADVVSTVLRVVSGLRFLHNTEFAHATMTALVPKVGDLSPARLADAFFSASLLDPTDVSGLNAKLEERFLREFTSFPIKDTVTMFQTVTVRRHSTPELAAQVAPLVAAQAHQLPVRHLRRALEGMVTAGWKDTAEIPLYAILAKQAARLVLGKQSAATSAILGKHVDNQGYQRTPVQLLRQLARIFANTGLKAGPGANQPLAPYFAALQRELEGRLAELDEQVTDDFAESFKKVGIAEGARVQI 8a22 Am 2.91 BS01 rna A7 0 L3 K4 N90 S94 V115 L2 K3 N89 S93 V114 36253367 1 ~ 576 PLKPLVFRPLKLFFWATNRHVHAKVVRFSSPFNEGVPVVDISTFDAFNKLKGSAPVVAPRSLECYKEVAKMVKEETARQNINEVTLHLNSHASDRGVREVVRELKNLGLLVKKV 8a22 AM 2.91 BS02 rna A5 0 R56 E62 Y63 Q102 R105 R111 N138 M140 D141 F147 S151 T181 R184 S187 R216 F222 Q260 T261 V264 R266 R293 E297 Q351 R57 E63 Y64 Q103 R106 R112 N139 M141 D142 F148 S152 T182 R185 S188 R217 F223 Q261 T262 V265 R267 R294 E298 Q352 36253367 1 ~ 142 TIFNTGVPGPRPEVAQKLSTEYQGHILRMISLAESASELDEVLWSSKKHLRPVHIARSCLKLEYLRTKEKGREVSEPIKNLASELENYVELYSTKFTIGQVSQLVRGLSSIRRNIQPDLLLKLAAVVVADDGRQVQLANEMDCRDLFFGFFSQGFDNELFWKRLSESVLPRLPYFNADVVSTVLRVVSGLRFLHNTEFAHATMTALVPKVGDLSPARLADAFFSASLLDPTDVSGLNAKLEERFLREFTSFPIKDTVTMFQTVTVRRHSTPELAAQVAPLVAAQAHQLPVRHLRRALEGMVTAGWKDTAEIPLYAILAKQAARLVLGKQSAATSAILGKHVDNQGYQRTPVQLLRQLARIFANTGLKAGPGANQPLAPYFAALQRELEGRLAELDEQVTDDFAESFKKVGIAEGARVQI 8a22 Am 2.91 BS02 rna A9 0 T18 N19 R20 H21 H23 S43 F45 V58 T17 N18 R19 H20 H22 S42 F44 V57 36253367 51 ~ 129 PLKPLVFRPLKLFFWATNRHVHAKVVRFSSPFNEGVPVVDISTFDAFNKLKGSAPVVAPRSLECYKEVAKMVKEETARQNINEVTLHLNSHASDRGVREVVRELKNLGLLVKKV 8a22 AM 2.91 BS03 rna A6 0 T19 E20 T20 E21 36253367 1 ~ 132 TIFNTGVPGPRPEVAQKLSTEYQGHILRMISLAESASELDEVLWSSKKHLRPVHIARSCLKLEYLRTKEKGREVSEPIKNLASELENYVELYSTKFTIGQVSQLVRGLSSIRRNIQPDLLLKLAAVVVADDGRQVQLANEMDCRDLFFGFFSQGFDNELFWKRLSESVLPRLPYFNADVVSTVLRVVSGLRFLHNTEFAHATMTALVPKVGDLSPARLADAFFSASLLDPTDVSGLNAKLEERFLREFTSFPIKDTVTMFQTVTVRRHSTPELAAQVAPLVAAQAHQLPVRHLRRALEGMVTAGWKDTAEIPLYAILAKQAARLVLGKQSAATSAILGKHVDNQGYQRTPVQLLRQLARIFANTGLKAGPGANQPLAPYFAALQRELEGRLAELDEQVTDDFAESFKKVGIAEGARVQI 8a22 AM 2.91 BS04 rna A7 0 T0 I1 T1 I2 36253367 1 ~ 576 TIFNTGVPGPRPEVAQKLSTEYQGHILRMISLAESASELDEVLWSSKKHLRPVHIARSCLKLEYLRTKEKGREVSEPIKNLASELENYVELYSTKFTIGQVSQLVRGLSSIRRNIQPDLLLKLAAVVVADDGRQVQLANEMDCRDLFFGFFSQGFDNELFWKRLSESVLPRLPYFNADVVSTVLRVVSGLRFLHNTEFAHATMTALVPKVGDLSPARLADAFFSASLLDPTDVSGLNAKLEERFLREFTSFPIKDTVTMFQTVTVRRHSTPELAAQVAPLVAAQAHQLPVRHLRRALEGMVTAGWKDTAEIPLYAILAKQAARLVLGKQSAATSAILGKHVDNQGYQRTPVQLLRQLARIFANTGLKAGPGANQPLAPYFAALQRELEGRLAELDEQVTDDFAESFKKVGIAEGARVQI 8a22 AN 2.91 BS01 rna A2 0 K18 Q24 G25 I27 L28 R29 H50 R52 H55 E64 Y65 R107 S111 R113 D143 F149 S153 R186 R218 F224 S225 Q262 T263 V266 Q353 Q357 K18 Q24 G25 I27 L28 R29 H50 R52 H55 E64 Y65 R107 S111 R113 D143 F149 S153 R186 R218 F224 S225 Q262 T263 V266 Q353 Q357 36253367 1 ~ 81 GTIFNTGVPGPRPEVAQKLSTEYQGHILRMISLAESASELDEVLWSSKKHLRPVHIARSCLKLEYLRTKEKGREVSEPIKNLASELENYVELYSTKFTIGQVSQLVRGLSSIRRNIQPDLLLKLAAVVVADDGRQVQLANEMDCRDLFFGFFSQGFDNELFWKRLSESVLPRLPYFNADVVSTVLRVVSGLRFLHNTEFAHATMTALVPKVGDLSPARLADAFFSASLLDPTDVSGLNAKLEERFLREFTSFPIKDTVTMFQTVTVRRHSTPELAAQVAPLVAAQAHQLPVRHLRRALEGMVTAGWKDTAEIPLYAILAKQAARLVLGKQSAATSAILGKHVDNQGYQRTPVQLLRQLARIFANTGLKAGPGANQPLAPYFAALQRELEGRLAELDEQVTDDFAESFKKVGIAEGARVQI 8a22 An 2.91 BS01 rna A8 0 Q74 R75 R77 A81 K94 R96 N97 R99 Q103 F104 D107 E110 T111 R156 R158 Q22 R23 R25 A29 K42 R44 N45 R47 Q51 F52 D55 E58 T59 R104 R106 0003735,0005840,0006412 36253367 1 ~ 350 EVIIPTIPKYANPYKLTPGVSQRLRTPKALYEPWCPSRLLLKKRNVRARMQFLLDVLETEKEVEFQKQRNYPDFKVGDVLDVTMVAAENERKTYVHRGLCIQKRDRGYGSSFKLYCVFSDSGGFIQHLPLCMPDILDIKIVGQVDYKDEEDLKELVESESRECKFLDKVL 8a22 AN 2.91 BS02 rna A7 0 G1 T6 G10 G1 T6 G10 36253367 1 ~ 576 GTIFNTGVPGPRPEVAQKLSTEYQGHILRMISLAESASELDEVLWSSKKHLRPVHIARSCLKLEYLRTKEKGREVSEPIKNLASELENYVELYSTKFTIGQVSQLVRGLSSIRRNIQPDLLLKLAAVVVADDGRQVQLANEMDCRDLFFGFFSQGFDNELFWKRLSESVLPRLPYFNADVVSTVLRVVSGLRFLHNTEFAHATMTALVPKVGDLSPARLADAFFSASLLDPTDVSGLNAKLEERFLREFTSFPIKDTVTMFQTVTVRRHSTPELAAQVAPLVAAQAHQLPVRHLRRALEGMVTAGWKDTAEIPLYAILAKQAARLVLGKQSAATSAILGKHVDNQGYQRTPVQLLRQLARIFANTGLKAGPGANQPLAPYFAALQRELEGRLAELDEQVTDDFAESFKKVGIAEGARVQI 8a22 Ao 2.91 BS01 rna A2 0 R10 F20 R23 Y28 K29 R33 R34 R37 G38 H41 S42 E48 K49 R4 F14 R17 Y22 K23 R27 R28 R31 G32 H35 S36 E42 K43 0003735,0005840,0006412,0019843 36253367 1 ~ 81 TFSREQVFTFAKNFTGRARNVYKVALRRVERGLQHSYVGRKEKKRTIRSLWIQRINAGCREHGFAYSALINGLNQENIQLNRKVLSELAMHEPDSFKAVLDQVRFMKGQEIYANVEP 8a22 AO 2.91 BS01 rna A8 0 Y1 T2 F5 R8 R92 K94 W95 R110 W111 E148 R189 Y1 T2 F5 R8 R92 K94 W95 R110 W111 E148 R189 36253367 1 ~ 350 YTWHFLSRQRVEAVNKATDILELEDIMRLEGNKYDYIAIRAFLKRVCILLQERADALGLPPSNEGLLVRFDEPERARYEALVSQVCDVVSARAKWFDPSNAAAVAYCLTRWLGRAEAPLIEQLLRRVVARLPEAKSKDVQYALDATLESAAAPHLEHLREPMLRAAGAFLGAKLPTGRVPPEVVAKITRLLVNHWDQPDEELLEAIVTDIAVRLEIYSPTALGRTLLALSKVPALTGAAFKRSRSSFLPEGVNVPSGADVAVPLADACLAHVAAHAAEHANEHDLIKFLGAISKLASPGRAATAGADAGAEATESGAAWAKRNSASLAWFALEQRLAPSTRGSFEGNQFPFVIKLVSAAARPPPAVTKFISSTVAKE 8a22 Ao 2.91 BS02 rna A4 0 Y43 R46 K49 K50 R51 I53 R54 W57 Q59 N62 R66 N87 R88 K89 Y37 R40 K43 K44 R45 I47 R48 W51 Q53 N56 R60 N81 R82 K83 0003735,0005840,0006412,0019843 36253367 1 ~ 73 TFSREQVFTFAKNFTGRARNVYKVALRRVERGLQHSYVGRKEKKRTIRSLWIQRINAGCREHGFAYSALINGLNQENIQLNRKVLSELAMHEPDSFKAVLDQVRFMKGQEIYANVEP 8a22 Ao 2.91 BS03 rna A5 0 K47 R51 R54 S73 N77 K41 R45 R48 S67 N71 0003735,0005840,0006412,0019843 36253367 1 ~ 142 TFSREQVFTFAKNFTGRARNVYKVALRRVERGLQHSYVGRKEKKRTIRSLWIQRINAGCREHGFAYSALINGLNQENIQLNRKVLSELAMHEPDSFKAVLDQVRFMKGQEIYANVEP 8a22 Ao 2.91 BS04 rna A6 0 K29 R33 K23 R27 0003735,0005840,0006412,0019843 36253367 1 ~ 132 TFSREQVFTFAKNFTGRARNVYKVALRRVERGLQHSYVGRKEKKRTIRSLWIQRINAGCREHGFAYSALINGLNQENIQLNRKVLSELAMHEPDSFKAVLDQVRFMKGQEIYANVEP 8a22 Ap 2.91 BS01 rna A2 0 R151 K153 R154 R151 K153 R154 0003723,0003735,0005840,0006412 36253367 1 ~ 81 VRTKLPSKRPFLQTASHLAVNSLVPSVRTNRWADLIKGPAVRSCIPEIPEVPKPSEYTTIGTIEGPYTLNLERVFGVVELAGSQYKVTPDDVIFTNLLHGIEVNEVVMLERVMLLGSRSNTIIGRPYIPGACVLAAVEEHFLDGTVHVFKRKKRKRYRRYKPTRPMMTTLRILKVLGIDPAPGDELGIPSGPVIKITNTE 8a22 Ap 2.91 BS02 rna A3 0 R2 K4 H17 N21 R159 R2 K4 H17 N21 R159 0003723,0003735,0005840,0006412 36253367 1 ~ 210 VRTKLPSKRPFLQTASHLAVNSLVPSVRTNRWADLIKGPAVRSCIPEIPEVPKPSEYTTIGTIEGPYTLNLERVFGVVELAGSQYKVTPDDVIFTNLLHGIEVNEVVMLERVMLLGSRSNTIIGRPYIPGACVLAAVEEHFLDGTVHVFKRKKRKRYRRYKPTRPMMTTLRILKVLGIDPAPGDELGIPSGPVIKITNTE 8a22 Ap 2.91 BS03 rna A4 0 K150 K155 K150 K155 0003723,0003735,0005840,0006412 36253367 1 ~ 73 VRTKLPSKRPFLQTASHLAVNSLVPSVRTNRWADLIKGPAVRSCIPEIPEVPKPSEYTTIGTIEGPYTLNLERVFGVVELAGSQYKVTPDDVIFTNLLHGIEVNEVVMLERVMLLGSRSNTIIGRPYIPGACVLAAVEEHFLDGTVHVFKRKKRKRYRRYKPTRPMMTTLRILKVLGIDPAPGDELGIPSGPVIKITNTE 8a22 Ap 2.91 BS04 rna A6 0 R156 Y157 R156 Y157 0003723,0003735,0005840,0006412 36253367 1 ~ 132 VRTKLPSKRPFLQTASHLAVNSLVPSVRTNRWADLIKGPAVRSCIPEIPEVPKPSEYTTIGTIEGPYTLNLERVFGVVELAGSQYKVTPDDVIFTNLLHGIEVNEVVMLERVMLLGSRSNTIIGRPYIPGACVLAAVEEHFLDGTVHVFKRKKRKRYRRYKPTRPMMTTLRILKVLGIDPAPGDELGIPSGPVIKITNTE 8a22 Ap 2.91 BS05 rna A7 0 V1 R2 T3 L5 V1 R2 T3 L5 0003723,0003735,0005840,0006412 36253367 1 ~ 576 VRTKLPSKRPFLQTASHLAVNSLVPSVRTNRWADLIKGPAVRSCIPEIPEVPKPSEYTTIGTIEGPYTLNLERVFGVVELAGSQYKVTPDDVIFTNLLHGIEVNEVVMLERVMLLGSRSNTIIGRPYIPGACVLAAVEEHFLDGTVHVFKRKKRKRYRRYKPTRPMMTTLRILKVLGIDPAPGDELGIPSGPVIKITNTE 8a22 Aq 2.91 BS01 rna A1 0 R75 Y119 R138 Y187 K190 R216 R8 Y52 R71 Y120 K123 R149 0003735,0005840,0006412,0015934 36253367 1 ~ 109 SRPPLYARSGKFRESEEVQPYRTWYWYDAETESEERRKELRQQLYRDSGMSYYLNIPQSMKKLERVVRVIRNLAYDEAWKQACVLPLKAAGFVKEGLEHARKDAEEKGLDPKKLVVSTVYTAKGKYLRGFQPMGKGFAGRKTTRKTHLRIVLRENASVLPFAAQVVSPSRVGGASQKHLRDISVRYTV 8a22 Aq 2.91 BS02 rna A3 0 G201 K202 F204 G134 K135 F137 0003735,0005840,0006412,0015934 36253367 1 ~ 210 SRPPLYARSGKFRESEEVQPYRTWYWYDAETESEERRKELRQQLYRDSGMSYYLNIPQSMKKLERVVRVIRNLAYDEAWKQACVLPLKAAGFVKEGLEHARKDAEEKGLDPKKLVVSTVYTAKGKYLRGFQPMGKGFAGRKTTRKTHLRIVLRENASVLPFAAQVVSPSRVGGASQKHLRDISVRYTV 8a22 Aq 2.91 BS03 rna A6 0 S126 K128 R207 R211 S59 K61 R140 R144 0003735,0005840,0006412,0015934 36253367 1 ~ 132 SRPPLYARSGKFRESEEVQPYRTWYWYDAETESEERRKELRQQLYRDSGMSYYLNIPQSMKKLERVVRVIRNLAYDEAWKQACVLPLKAAGFVKEGLEHARKDAEEKGLDPKKLVVSTVYTAKGKYLRGFQPMGKGFAGRKTTRKTHLRIVLRENASVLPFAAQVVSPSRVGGASQKHLRDISVRYTV 8a22 Aq 2.91 BS04 rna A7 0 Q125 K129 K155 Q198 P199 M200 G203 F204 R207 K208 T209 Q58 K62 K88 Q131 P132 M133 G136 F137 R140 K141 T142 0003735,0005840,0006412,0015934 36253367 1 ~ 576 SRPPLYARSGKFRESEEVQPYRTWYWYDAETESEERRKELRQQLYRDSGMSYYLNIPQSMKKLERVVRVIRNLAYDEAWKQACVLPLKAAGFVKEGLEHARKDAEEKGLDPKKLVVSTVYTAKGKYLRGFQPMGKGFAGRKTTRKTHLRIVLRENASVLPFAAQVVSPSRVGGASQKHLRDISVRYTV 8a22 Aq 2.91 BS05 rna A8 0 Q243 K244 L246 R247 R252 Y253 Q176 K177 L179 R180 R185 Y186 0003735,0005840,0006412,0015934 36253367 1 ~ 350 SRPPLYARSGKFRESEEVQPYRTWYWYDAETESEERRKELRQQLYRDSGMSYYLNIPQSMKKLERVVRVIRNLAYDEAWKQACVLPLKAAGFVKEGLEHARKDAEEKGLDPKKLVVSTVYTAKGKYLRGFQPMGKGFAGRKTTRKTHLRIVLRENASVLPFAAQVVSPSRVGGASQKHLRDISVRYTV 8a22 Aq 2.91 BS06 peptide Xi 0 S118 Y119 Y120 L121 H166 S51 Y52 Y53 L54 H99 0003735,0005840,0006412,0015934 36253367 8 ~ 31 SRPPLYARSGKFRESEEVQPYRTWYWYDAETESEERRKELRQQLYRDSGMSYYLNIPQSMKKLERVVRVIRNLAYDEAWKQACVLPLKAAGFVKEGLEHARKDAEEKGLDPKKLVVSTVYTAKGKYLRGFQPMGKGFAGRKTTRKTHLRIVLRENASVLPFAAQVVSPSRVGGASQKHLRDISVRYTV 8a22 Ar 2.91 BS01 rna A6 0 Q79 E118 K129 N148 T149 Y152 R155 K175 Y177 K213 Q28 E67 K78 N97 T98 Y101 R104 K124 Y126 K155 0003735,0005840,0006412 36253367 1 ~ 132 DYLLDDDINGDPSNPLNKPMHFGSFQKQRQPNSFRRLPICFPDIKLTLMKLEEHQLEQIKQTGWLREAAFKTTPNTTKLEIKAFLESVYGMEVERVNTANYLGRKRVVYTGKAKELYREDDYKKAYVIFKKPEGLSLPETRPLLQKLVDIKLKRK 8a22 Ar 2.91 BS02 rna A7 0 T128 K129 N151 T77 K78 N100 0003735,0005840,0006412 36253367 1 ~ 576 DYLLDDDINGDPSNPLNKPMHFGSFQKQRQPNSFRRLPICFPDIKLTLMKLEEHQLEQIKQTGWLREAAFKTTPNTTKLEIKAFLESVYGMEVERVNTANYLGRKRVVYTGKAKELYREDDYKKAYVIFKKPEGLSLPETRPLLQKLVDIKLKRK 8a22 Ar 2.91 BS03 peptide Xi 0 V158 Y160 V107 Y109 0003735,0005840,0006412 36253367 8 ~ 31 DYLLDDDINGDPSNPLNKPMHFGSFQKQRQPNSFRRLPICFPDIKLTLMKLEEHQLEQIKQTGWLREAAFKTTPNTTKLEIKAFLESVYGMEVERVNTANYLGRKRVVYTGKAKELYREDDYKKAYVIFKKPEGLSLPETRPLLQKLVDIKLKRK 8a22 At 2.91 BS01 rna A9 0 I58 S59 R63 Y64 R92 K94 K96 K97 R99 Y102 R104 H114 K118 F123 H124 N125 L187 Q191 R197 R267 I24 S25 R29 Y30 R58 K60 K62 K63 R65 Y68 R70 H80 K84 F89 H90 N91 L153 Q157 R163 R233 0003735,0005840,0006412 36253367 51 ~ 129 QVVPSEIIRPLESINSFLEVKSNISGRIRYELYSSELKFSFPKHDIEEGLLELTAYARTKTKKSRAKYLREDGNIPTVIHGFDKATCGFHNLNLCIPEKEANAMVRKYGRNGCAARVVKVKVVDHANPEKVFGYLRTRPCSLAITATSLKLELMHLQYCPQDRLVDVRVPIRLINDDVAPGVKKGGWISVKQRLVGYQCRGNSIPPHIEVDAKHLRLDDKVLKRDLPIPKGTRLLGCDFDAVVLHCTTDVGKE 8a22 Au 2.91 BS01 rna A7 0 Q60 S64 H65 A66 K67 N68 G82 I84 R87 K89 Q90 G91 G102 R103 D104 Y105 F108 R124 K126 R128 R155 N181 Q1 S5 H6 A7 K8 N9 G23 I25 R28 K30 Q31 G32 G43 R44 D45 Y46 F49 R65 K67 R69 R96 N122 0003735,0005840,0006412 36253367 1 ~ 576 QGGKSHAKNWGPKFGDGEIVFPGMIIMRQKQGIYSPGYNVGRGRDYTIFAKTVGYVEYSKLKTERGKTRRYIHVVPINDDWSPEYQKLADELVVRRAEVKRQILGHHVHTEPAFHFSLPQRNGNMSWLLNSVHKFPGTTTLA 8a22 Au 2.91 BS02 rna A8 0 L188 S190 L129 S131 0003735,0005840,0006412 36253367 1 ~ 350 QGGKSHAKNWGPKFGDGEIVFPGMIIMRQKQGIYSPGYNVGRGRDYTIFAKTVGYVEYSKLKTERGKTRRYIHVVPINDDWSPEYQKLADELVVRRAEVKRQILGHHVHTEPAFHFSLPQRNGNMSWLLNSVHKFPGTTTLA 8a22 Av 2.91 BS01 rna A7 0 R67 R81 R83 F85 Q97 Q99 Q120 R25 R39 R41 F43 Q55 Q57 Q78 0003735 36253367 1 ~ 576 QQKNVEIARKLLPLAKKQLKGLLDRQDNVLWGKTDIVIRKRTFKKNDEELYSLVQVQWLDVKLWSNILQERVPLTLSQETLTHIESIGGLDDYLLKTPDSQMKSNFSSDLRWRVVCEAMKQGEAESKQK 8a22 Ax 2.91 BS01 rna A1 0 V133 R138 F142 D146 S150 K176 R177 R179 V130 R135 F139 D143 S147 K173 R174 R176 0003735,0006412,0015934 36253367 1 ~ 109 EPVRSLFVTLRRSYIGKAWFHREILQNFRLKKIRQTVEVANTPSARNSLAKIPHLVTIETDKMYYLRNMKKFYEQLLRPPVQVSHEHAALSSEIKPVHNLHSKHVQERLQEHAYPSKMEGYVLHEKKPVVPRALRSFAFKSQDEHKSFVLARLGIFSEEAKKIHLNELRTFAKRDR 8a22 Ax 2.91 BS02 rna A2 0 H101 S105 H107 H98 S102 H104 0003735,0006412,0015934 36253367 1 ~ 81 EPVRSLFVTLRRSYIGKAWFHREILQNFRLKKIRQTVEVANTPSARNSLAKIPHLVTIETDKMYYLRNMKKFYEQLLRPPVQVSHEHAALSSEIKPVHNLHSKHVQERLQEHAYPSKMEGYVLHEKKPVVPRALRSFAFKSQDEHKSFVLARLGIFSEEAKKIHLNELRTFAKRDR 8a22 Ax 2.91 BS03 rna A4 0 R15 S16 I18 G19 K20 A21 W22 R37 R12 S13 I15 G16 K17 A18 W19 R34 0003735,0006412,0015934 36253367 1 ~ 73 EPVRSLFVTLRRSYIGKAWFHREILQNFRLKKIRQTVEVANTPSARNSLAKIPHLVTIETDKMYYLRNMKKFYEQLLRPPVQVSHEHAALSSEIKPVHNLHSKHVQERLQEHAYPSKMEGYVLHEKKPVVPRALRSFAFKSQDEHKSFVLARLGIFSEEAKKIHLNELRTFAKRDR 8a22 Az 2.91 BS01 rna A1 0 R87 R88 R12 R13 0003735,0006412,0015934 36253367 1 ~ 109 AVPKKKLSVFRRRNRRIWYWKKASPIIGQCSHCGFVGPSGVLGLSPIAKCYPTEYKPPC 8a22 Az 2.91 BS02 rna A6 0 K81 L82 R87 R91 K6 L7 R12 R16 0003735,0006412,0015934 36253367 1 ~ 132 AVPKKKLSVFRRRNRRIWYWKKASPIIGQCSHCGFVGPSGVLGLSPIAKCYPTEYKPPC 8a22 Az 2.91 BS03 rna A7 0 V77 K79 K80 K81 R86 N89 I92 V2 K4 K5 K6 R11 N14 I17 0003735,0006412,0015934 36253367 1 ~ 576 AVPKKKLSVFRRRNRRIWYWKKASPIIGQCSHCGFVGPSGVLGLSPIAKCYPTEYKPPC 8a22 Az 2.91 BS04 rna A8 0 A76 V77 P78 R90 K97 I101 A1 V2 P3 R15 K22 I26 0003735,0006412,0015934 36253367 1 ~ 350 AVPKKKLSVFRRRNRRIWYWKKASPIIGQCSHCGFVGPSGVLGLSPIAKCYPTEYKPPC 8a22 Ba 2.91 BS01 peptide Ui 0 L204 N205 G217 V219 V235 R253 L189 N190 G202 V204 V220 R238 36253367 1 ~ 26 VSLPMTKAELRASLLYKMRKDTLTKVIDSSLSTSVLTIEEKEKIDRTLYAHIETENNHIDPGLHCLIRALRRSNLTMPILKGQQIQAKVIQKTDEVMLLDPGFYNLSEVPVNYLTTAHIVRKVDDSPRENLYDVRPGDVVKVLVDDVYTPYGDMQLDVPQQDPRLILNQVWDELHLKMKKKELVRGRILNECKSGYAVGVAGFVALLPYANTSREVANRVGEAQSFQIKSMSEPHRRRIVLQ 8a22 Ba 2.91 BS02 peptide Uj 0 N233 R234 V235 E237 N218 R219 V220 E222 36253367 1 ~ 9 VSLPMTKAELRASLLYKMRKDTLTKVIDSSLSTSVLTIEEKEKIDRTLYAHIETENNHIDPGLHCLIRALRRSNLTMPILKGQQIQAKVIQKTDEVMLLDPGFYNLSEVPVNYLTTAHIVRKVDDSPRENLYDVRPGDVVKVLVDDVYTPYGDMQLDVPQQDPRLILNQVWDELHLKMKKKELVRGRILNECKSGYAVGVAGFVALLPYANTSREVANRVGEAQSFQIKSMSEPHRRRIVLQ 8a22 BB 2.91 BS01 rna B3 0 S20 R21 S10 R11 36253367 13 ~ 391 PWQLKEPDNSRVVKNLVKPSKPCGKELLALIDCTRRNFSGDADGTCMRERAALARCSSQRKKTSKGEILNHLKNLAASWKRFGF 8a22 BB 2.91 BS02 rna B4 0 P11 W12 D18 R21 N25 P1 W2 D8 R11 N15 36253367 2 ~ 349 PWQLKEPDNSRVVKNLVKPSKPCGKELLALIDCTRRNFSGDADGTCMRERAALARCSSQRKKTSKGEILNHLKNLAASWKRFGF 8a22 BC 2.91 BS01 rna A7 0 M142 R143 V144 M25 R26 V27 36253367 1 ~ 576 ITTMQWRKLKIKKHKLRKRRKANRMRVVKVR 8a22 Bc 2.91 BS01 rna B4 0 R17 R21 K146 R148 K155 F169 H172 R185 M186 A188 R192 R209 R17 R21 K146 R148 K155 F169 H172 R185 M186 A188 R192 R209 0003735,0006412 36253367 2 ~ 349 NNPNPPQIRLLDLVVQRERLRPKNPRDIELLSAEQTDLAKTLITPPTEEGAEPPAAPQLAGLKQVGLPLNQRDVVSVLHQSLSNAVGQNVHFRPFFFSNLFQSAPAVAQYVAHALETGSAWNRVERFFVSSVEGDPNLLGMQVQVKGRLGTKAGKGMKKHWKYGDLDIFTIHDYVDYGRATAFTRMGAIGVRVWLKYKPEAVKDVYFQRQTNFTMPLSKLLSMPRPPLPLSVDGATSSCWWTRPAPLQPPENLTEQSFASGCAGYDPATRKLRDPQEIKALLEELDRRE 8a22 BC 2.91 BS02 rna B3 0 W123 K129 R148 W6 K12 R31 36253367 13 ~ 391 ITTMQWRKLKIKKHKLRKRRKANRMRVVKVR 8a22 BC 2.91 BS03 rna B4 0 I118 M121 W123 R124 K127 I128 K130 H131 K132 R134 I1 M4 W6 R7 K10 I11 K13 H14 K15 R17 36253367 2 ~ 349 ITTMQWRKLKIKKHKLRKRRKANRMRVVKVR 8a22 BD 2.91 BS01 rna B2 0 F167 R334 F99 R266 36253367 1 ~ 214 PSVNDLASLLSLSEQYRGADVLAEGAALPGTGFANARGTFLPHELPTAIEYLKELDPEAEMKLEQMEAMYKLLYSRNESEREVGRQMMYDLLKLSGHPFRELELCNWDYMAAFLDARVAGRVFHRGSGERLVHRTATFPAFEGYPLAEVDQTTEGEVSKLNREESKRQDNAMFQDFRKKLLFNLGMVGEQLWEPVQGVLSANLRSALDRPLVVYDITAATGETVYPPKFVAEVDGTRRALNEQERAYQAKRKPGPRLPYYMRRIARKEEL 8a22 Bd 2.91 BS01 rna B2 0 Q173 N174 T177 G180 M185 K186 H187 S200 A201 S203 L204 Q173 N174 T177 G180 M185 K186 H187 S200 A201 S203 L204 36253367 1 ~ 214 VYRNSHTKRFSCRNSRLKYPFEQIWPTLQLSEDDAAMFRRNSRQFVVDLSQNITLKNKFALNKATKIPHQDARALIYESNLHLDAVGEHPRYLKIRRVTSQYGSKLMNVRKLRLLLGFKRRNFVQKLYEHTLLQQGSNKSWKVLCALEAKMNLAVTRMGVAEDVLEATHDLRQNNVTLNGSPAQMKHARYLEPADVLAVSAVSLIKQRICKGLFEVAPNTL 8a22 Bd 2.91 BS02 rna B3 0 V1 R3 R13 Y102 R120 R121 N122 V1 R3 R13 Y102 R120 R121 N122 36253367 13 ~ 391 VYRNSHTKRFSCRNSRLKYPFEQIWPTLQLSEDDAAMFRRNSRQFVVDLSQNITLKNKFALNKATKIPHQDARALIYESNLHLDAVGEHPRYLKIRRVTSQYGSKLMNVRKLRLLLGFKRRNFVQKLYEHTLLQQGSNKSWKVLCALEAKMNLAVTRMGVAEDVLEATHDLRQNNVTLNGSPAQMKHARYLEPADVLAVSAVSLIKQRICKGLFEVAPNTL 8a22 BE 2.91 BS01 rna B1 0 I77 A78 I1 A2 36253367 1 ~ 102 IAPSQLDKLEKFVHVRPPKTDYEEDIKQAISSVTDNEGLKKCLDLFLTNHAAQTWVGKHEYANAGQVSDFIKVCEKVGSSAPLVTLWQSAYRYGVDPTVPLLRSSAAACAALGEGADAALVLLYGSCYIVNVPEDLAAAVRTALEAHEKAQEGNAEALAKVQKYREALDRL 8a22 Be 2.91 BS01 rna B1 0 R19 L21 R92 R100 W104 R107 C108 N134 P170 V172 T182 R56 L58 R129 R137 W141 R144 C145 N171 P207 V209 T219 0003723,0003735,0005840,0006412 36253367 1 ~ 102 INMDQYLRMDNQDTLELLVQAKDNFLKKDERTIPIPQSVREVMYRHRWDKVIVDVRRLVYRTKNNKREQYTAMVASGNQKGLLGLGMGSAETAQLAVARAYLDSFSNLAAVPLYRGHTVYHHVEHHFQRVKVTLSPRTSGWGLRCSNLFYELCSLAGIRDLTVDVSGATRNKFFVAKAFFDALQKQTAPHDGVEGTGVYVKEVVRRPVVNLGTYRNNGTLPPKEYLAT 8a22 Be 2.91 BS02 rna B2 0 N173 G175 R178 N179 N210 G212 R215 N216 0003723,0003735,0005840,0006412 36253367 1 ~ 214 INMDQYLRMDNQDTLELLVQAKDNFLKKDERTIPIPQSVREVMYRHRWDKVIVDVRRLVYRTKNNKREQYTAMVASGNQKGLLGLGMGSAETAQLAVARAYLDSFSNLAAVPLYRGHTVYHHVEHHFQRVKVTLSPRTSGWGLRCSNLFYELCSLAGIRDLTVDVSGATRNKFFVAKAFFDALQKQTAPHDGVEGTGVYVKEVVRRPVVNLGTYRNNGTLPPKEYLAT 8a22 Be 2.91 BS03 rna B3 0 R24 K26 R61 K63 0003723,0003735,0005840,0006412 36253367 13 ~ 391 INMDQYLRMDNQDTLELLVQAKDNFLKKDERTIPIPQSVREVMYRHRWDKVIVDVRRLVYRTKNNKREQYTAMVASGNQKGLLGLGMGSAETAQLAVARAYLDSFSNLAAVPLYRGHTVYHHVEHHFQRVKVTLSPRTSGWGLRCSNLFYELCSLAGIRDLTVDVSGATRNKFFVAKAFFDALQKQTAPHDGVEGTGVYVKEVVRRPVVNLGTYRNNGTLPPKEYLAT 8a22 Be 2.91 BS04 rna B4 0 R24 N27 R61 N64 0003723,0003735,0005840,0006412 36253367 2 ~ 349 INMDQYLRMDNQDTLELLVQAKDNFLKKDERTIPIPQSVREVMYRHRWDKVIVDVRRLVYRTKNNKREQYTAMVASGNQKGLLGLGMGSAETAQLAVARAYLDSFSNLAAVPLYRGHTVYHHVEHHFQRVKVTLSPRTSGWGLRCSNLFYELCSLAGIRDLTVDVSGATRNKFFVAKAFFDALQKQTAPHDGVEGTGVYVKEVVRRPVVNLGTYRNNGTLPPKEYLAT 8a22 BF 2.91 BS01 rna B1 0 W235 I276 K283 R356 F359 H360 G363 I366 Y391 A397 R400 W164 I205 K212 R285 F288 H289 G292 I295 Y320 A326 R329 36253367 1 ~ 102 MATIPKGLDIDPESPMLYHYFKSIHPHQVSFRIKKRKQLQHLWELCKLYENKMDTLASAAMLGQLFRLQKRNNPDYSVELANQIFEHCVKRLSFTIRFATYQEIVPVLFTLARMNVSIVPSDTLLLDPTHRVSREFVHLFLKRAVRNHVHIRVVNPRQMARVLWATAKLFPEDQRMDPRVQDAVDKLARSSVKRLSELHPGSLSIYASAFAKLSPAPTSQEGPLKDVDVSSWDATITGVKSSLLDLDSKELAFVARARTLKVFQGISREILLRVGDLNHEQFTVRNVFHVLGAYIRAQIQDPLVAKVLAENITGRIQDVYAEELIALVRAAERLDGFKNPDLTAAVLRRAREVDLPEETQKDYAKRLQSA 8a22 Bf 2.91 BS01 rna B3 0 Y2 R50 P52 F53 V73 R81 R88 V91 V92 R93 P95 R96 Q102 Y3 R51 P53 F54 V74 R82 R89 V92 V93 R94 P96 R97 Q103 0003735,0005840,0006412,0019843 36253367 13 ~ 391 PLYELLCLAKPLGKAEIAGAMKIVGQTVLKRGGFITEVQSYGEQQLAYDIRRPFEIYPSAHIFKMEFAAPTDIVRLVTHEMRVNENVLRWVVVRRPRFKHTLQELLEEVKAQENDDFKA 8a22 BF 2.91 BS02 rna B2 0 H74 H82 Q83 F86 R87 K89 K90 R91 K92 D109 L111 K125 R126 N128 Q157 P161 R168 R223 V224 N226 R228 R232 K264 E268 H270 H19 H27 Q28 F31 R32 K34 K35 R36 K37 D54 L56 K70 R71 N73 Q102 P106 R113 R152 V153 N155 R157 R161 K193 E197 H199 36253367 1 ~ 214 MATIPKGLDIDPESPMLYHYFKSIHPHQVSFRIKKRKQLQHLWELCKLYENKMDTLASAAMLGQLFRLQKRNNPDYSVELANQIFEHCVKRLSFTIRFATYQEIVPVLFTLARMNVSIVPSDTLLLDPTHRVSREFVHLFLKRAVRNHVHIRVVNPRQMARVLWATAKLFPEDQRMDPRVQDAVDKLARSSVKRLSELHPGSLSIYASAFAKLSPAPTSQEGPLKDVDVSSWDATITGVKSSLLDLDSKELAFVARARTLKVFQGISREILLRVGDLNHEQFTVRNVFHVLGAYIRAQIQDPLVAKVLAENITGRIQDVYAEELIALVRAAERLDGFKNPDLTAAVLRRAREVDLPEETQKDYAKRLQSA 8a22 BF 2.91 BS03 rna B4 0 M56 A57 H80 N106 K107 F149 R152 F153 R214 R217 M1 A2 H25 N51 K52 F94 R97 F98 R143 R146 36253367 2 ~ 349 MATIPKGLDIDPESPMLYHYFKSIHPHQVSFRIKKRKQLQHLWELCKLYENKMDTLASAAMLGQLFRLQKRNNPDYSVELANQIFEHCVKRLSFTIRFATYQEIVPVLFTLARMNVSIVPSDTLLLDPTHRVSREFVHLFLKRAVRNHVHIRVVNPRQMARVLWATAKLFPEDQRMDPRVQDAVDKLARSSVKRLSELHPGSLSIYASAFAKLSPAPTSQEGPLKDVDVSSWDATITGVKSSLLDLDSKELAFVARARTLKVFQGISREILLRVGDLNHEQFTVRNVFHVLGAYIRAQIQDPLVAKVLAENITGRIQDVYAEELIALVRAAERLDGFKNPDLTAAVLRRAREVDLPEETQKDYAKRLQSA 8a22 Bg 2.91 BS01 rna B4 0 Q129 I140 M144 M150 Q54 I65 M69 M75 0006412 36253367 2 ~ 349 KLREDNSGKDIKDVIDIVLQAVDNVKPLMQVDSNKTGTKVMHVPRPLKPRNQTQFAVKWIIEAAIKRCMASKRPMHECLAVEILLAYQKKGAARTKRDELHKLAMDNRANIA 8a22 Bh 2.91 BS01 rna B1 0 K135 R162 N163 Q180 K13 R40 N41 Q58 36253367 1 ~ 102 AAQAYFDLRYHVKKQGLLTVNRAASIINSIFPEFSHESHRNQLAVPLPRKEIPTYIMQNAKVQPWALLPTKAAAYAQYPNFFRSSSLFFGSLNREIVNRRPYSLLPADKLSMDLAQVCTNLGILNGWDIVQKREKLKDLDFVWPANELPRDHHEVKLFKHLHLRLALKWEQHKPLWEDGSMVKDQREYRDQQQVQQQQPLPHLPLAPLFGPLPLTVRNLSKASQPVLLYPLQLRELAQRMPSGLFLLYHHELGVITDAQAFLFDVPVVALAHVGLPVSMAAAVNGAVNRTFRAELGKPLREVTKLKDWSLSATIAAQVRERRQQLLERAEQTKRERKQIQDLVTVRVGKFKAEVDKEDSSLALQDELLAWQLKE 8a22 Bh 2.91 BS02 rna B2 0 H133 M179 N181 H11 M57 N59 36253367 1 ~ 214 AAQAYFDLRYHVKKQGLLTVNRAASIINSIFPEFSHESHRNQLAVPLPRKEIPTYIMQNAKVQPWALLPTKAAAYAQYPNFFRSSSLFFGSLNREIVNRRPYSLLPADKLSMDLAQVCTNLGILNGWDIVQKREKLKDLDFVWPANELPRDHHEVKLFKHLHLRLALKWEQHKPLWEDGSMVKDQREYRDQQQVQQQQPLPHLPLAPLFGPLPLTVRNLSKASQPVLLYPLQLRELAQRMPSGLFLLYHHELGVITDAQAFLFDVPVVALAHVGLPVSMAAAVNGAVNRTFRAELGKPLREVTKLKDWSLSATIAAQVRERRQQLLERAEQTKRERKQIQDLVTVRVGKFKAEVDKEDSSLALQDELLAWQLKE 8a22 Bh 2.91 BS03 rna B3 0 R171 N202 R205 G212 N215 R216 N220 N373 K376 S378 R49 N80 R83 G90 N93 R94 N98 N218 K221 S223 36253367 13 ~ 391 AAQAYFDLRYHVKKQGLLTVNRAASIINSIFPEFSHESHRNQLAVPLPRKEIPTYIMQNAKVQPWALLPTKAAAYAQYPNFFRSSSLFFGSLNREIVNRRPYSLLPADKLSMDLAQVCTNLGILNGWDIVQKREKLKDLDFVWPANELPRDHHEVKLFKHLHLRLALKWEQHKPLWEDGSMVKDQREYRDQQQVQQQQPLPHLPLAPLFGPLPLTVRNLSKASQPVLLYPLQLRELAQRMPSGLFLLYHHELGVITDAQAFLFDVPVVALAHVGLPVSMAAAVNGAVNRTFRAELGKPLREVTKLKDWSLSATIAAQVRERRQQLLERAEQTKRERKQIQDLVTVRVGKFKAEVDKEDSSLALQDELLAWQLKE 8a22 Bi 2.91 BS01 rna B3 0 W373 K375 W279 K281 0003735,0005840,0006412 36253367 13 ~ 391 SWQEHTVENFSIKPSYLSPLFATYQTETEKDDRRRLLLQLLKAHKLLSHEVEGLDSEQIQRGTRYRIAQMKELASDLRLLLKGDNQPINFTTCTDKSLMYGFYNLLESETSVWEHWASHFVEKYKGTPGLEPLEVIFSRQDPMLILEQAGACMTLDGVAETIGKRKSALAKVLMRRGTGKIIVNGLPYDAYFRDVEVRALMLQPFFACDGLGRFDVEVEVEGSGPSAQAQAIRTGIARALKLHYPDVPNADLEKLSIWDGRKVERKKPGRHKARRGFQWVKR 8a22 Bi 2.91 BS02 rna B4 0 A243 G244 K258 R259 K260 S317 S320 A321 R332 K335 W352 G354 R355 K356 V357 E358 R359 K360 K361 P362 G363 K366 R368 R369 Q372 V374 A149 G150 K164 R165 K166 S223 S226 A227 R238 K241 W258 G260 R261 K262 V263 E264 R265 K266 K267 P268 G269 K272 R274 R275 Q278 V280 0003735,0005840,0006412 36253367 2 ~ 349 SWQEHTVENFSIKPSYLSPLFATYQTETEKDDRRRLLLQLLKAHKLLSHEVEGLDSEQIQRGTRYRIAQMKELASDLRLLLKGDNQPINFTTCTDKSLMYGFYNLLESETSVWEHWASHFVEKYKGTPGLEPLEVIFSRQDPMLILEQAGACMTLDGVAETIGKRKSALAKVLMRRGTGKIIVNGLPYDAYFRDVEVRALMLQPFFACDGLGRFDVEVEVEGSGPSAQAQAIRTGIARALKLHYPDVPNADLEKLSIWDGRKVERKKPGRHKARRGFQWVKR 8a22 Bj 2.91 BS01 rna B3 0 V95 K97 R98 V87 K89 R90 0003735,0005840,0006412 36253367 13 ~ 391 NPTDSFYEIELTVKAYEERYVDMAVNALRDLLMISFTPKKFSPMGQGRYAKDIEPNNPIDLYIPTTMERVKVDWKKTRFTLIRGPFVDKRGMEQFERREYHSKIKASTTSLTELQWLLDALKLYEFTGVQIEAEVTSPGFVAAHEHQAVLKTSRPTHGEAGDFVDSLFLDDQSSILDAGHLRHIKDFVPSGFGSEMQTALAALRNVMHQGLEERRRALGMNSGYDAWLRQQQRVGSATVTKLFPASGLASSSSLLDEAATPADLSTLLLKSQIDSAAAVRDRKVAAFLAAVDAVFLNLRFDALEGHARFPFHFATAVPGQMKVPVAMWMQAVSKMAEYQRQVSEASQAADLLKAYTSYSAFSQALLYKLMQLWFETASSDAKEYLALPSWEEYEAMVQAKR 8a22 Bj 2.91 BS02 rna B4 0 R91 P93 F94 D96 R98 R106 R83 P85 F86 D88 R90 R98 0003735,0005840,0006412 36253367 2 ~ 349 NPTDSFYEIELTVKAYEERYVDMAVNALRDLLMISFTPKKFSPMGQGRYAKDIEPNNPIDLYIPTTMERVKVDWKKTRFTLIRGPFVDKRGMEQFERREYHSKIKASTTSLTELQWLLDALKLYEFTGVQIEAEVTSPGFVAAHEHQAVLKTSRPTHGEAGDFVDSLFLDDQSSILDAGHLRHIKDFVPSGFGSEMQTALAALRNVMHQGLEERRRALGMNSGYDAWLRQQQRVGSATVTKLFPASGLASSSSLLDEAATPADLSTLLLKSQIDSAAAVRDRKVAAFLAAVDAVFLNLRFDALEGHARFPFHFATAVPGQMKVPVAMWMQAVSKMAEYQRQVSEASQAADLLKAYTSYSAFSQALLYKLMQLWFETASSDAKEYLALPSWEEYEAMVQAKR 8a22 Bk 2.91 BS01 rna B3 0 G26 V28 W31 T33 S35 N41 A42 K44 R45 V103 Y105 R109 R112 R114 R115 G26 V28 W31 T33 S35 N41 A42 K44 R45 V103 Y105 R109 R112 R114 R115 0003735,0005840,0006412 36253367 13 ~ 391 VLQLEGVVHILNTSNNIVLTLTDKEGRVKAWTTPSSVGYKNAKKRLPVAAETAAGELAKRALALGYSTVAVKIKGIGTMTQYAVQMLSSSGIKITQLVDVTPVPYGGCRPSRKRRV 8a22 Bk 2.91 BS02 rna B4 0 R112 R115 R112 R115 0003735,0005840,0006412 36253367 2 ~ 349 VLQLEGVVHILNTSNNIVLTLTDKEGRVKAWTTPSSVGYKNAKKRLPVAAETAAGELAKRALALGYSTVAVKIKGIGTMTQYAVQMLSSSGIKITQLVDVTPVPYGGCRPSRKRRV 8a22 Bl 2.91 BS01 rna B1 0 Y29 S115 V119 R121 Y28 S114 V118 R120 0003735,0005840,0006412,0015935 36253367 1 ~ 102 LTVGQLLRGGRTKKVRRSKSPALEQCPYKKGICLRVYTTAPKKPNSANRKVCKVQLSNGYKVLAYIPGEGHNLQEHSIVLVRGGRTKDLPGVKYKVIRGKYDCAGVKGRKTSRSKYGVKRPKE 8a22 Bl 2.91 BS02 rna B2 0 P28 K30 P27 K29 0003735,0005840,0006412,0015935 36253367 1 ~ 214 LTVGQLLRGGRTKKVRRSKSPALEQCPYKKGICLRVYTTAPKKPNSANRKVCKVQLSNGYKVLAYIPGEGHNLQEHSIVLVRGGRTKDLPGVKYKVIRGKYDCAGVKGRKTSRSKYGVKRPKE 8a22 Bl 2.91 BS03 rna B3 0 Q6 R9 R12 K15 P28 N46 S47 A48 N49 R50 Y66 G69 E70 R83 G84 K88 D89 R110 K111 S113 S115 K116 Q5 R8 R11 K14 P27 N45 S46 A47 N48 R49 Y65 G68 E69 R82 G83 K87 D88 R109 K110 S112 S114 K115 0003735,0005840,0006412,0015935 36253367 13 ~ 391 LTVGQLLRGGRTKKVRRSKSPALEQCPYKKGICLRVYTTAPKKPNSANRKVCKVQLSNGYKVLAYIPGEGHNLQEHSIVLVRGGRTKDLPGVKYKVIRGKYDCAGVKGRKTSRSKYGVKRPKE 8a22 Bm 2.91 BS01 rna B3 0 C104 N105 K107 T108 R111 C103 N104 K106 T107 R110 0003676,0003723,0003735,0005840,0006412 36253367 13 ~ 391 VQIQRVTLPPHQCVYMALKKVFGLGGPTSLAVVEACGISKGVRVRDLKENHVQQITQFIQDNFVTEDNLRRKVREDIVKLVNIKSRDGLRHDWGVSIKGHTSCNGKTAKRLRH 8a22 Bm 2.91 BS02 rna B4 0 Q13 M17 K20 F23 G24 L25 G26 P28 T29 H92 W94 I98 K99 H101 S103 T108 K110 Q12 M16 K19 F22 G23 L24 G25 P27 T28 H91 W93 I97 K98 H100 S102 T107 K109 0003676,0003723,0003735,0005840,0006412 36253367 2 ~ 349 VQIQRVTLPPHQCVYMALKKVFGLGGPTSLAVVEACGISKGVRVRDLKENHVQQITQFIQDNFVTEDNLRRKVREDIVKLVNIKSRDGLRHDWGVSIKGHTSCNGKTAKRLRH 8a22 Bm 2.91 BS03 MG Bm 1 K20 V22 L25 K19 V21 L24 0003676,0003723,0003735,0005840,0006412 36253367 201 VQIQRVTLPPHQCVYMALKKVFGLGGPTSLAVVEACGISKGVRVRDLKENHVQQITQFIQDNFVTEDNLRRKVREDIVKLVNIKSRDGLRHDWGVSIKGHTSCNGKTAKRLRH 8a22 Bn 2.91 BS01 rna B3 0 R22 R29 R76 R88 R98 R22 R29 R76 R88 R98 0003735,0005840,0006412 36253367 13 ~ 391 TTKNFRLRFRIPQYPDIVGSRRIDKDQTRRVLYDQHEVDRRLYKAMTRDESLTLPVRLQVQRLFETEMPRDSAPSRIVDRCVLTGRVRGLVKFAGLSRIMLRQLIHYGHIGGVAKASW 8a22 Bn 2.91 BS02 rna B4 0 T2 K3 N4 F5 R6 I17 G19 R21 K44 R48 F64 R70 I99 R102 K115 S117 W118 T2 K3 N4 F5 R6 I17 G19 R21 K44 R48 F64 R70 I99 R102 K115 S117 W118 0003735,0005840,0006412 36253367 2 ~ 349 TTKNFRLRFRIPQYPDIVGSRRIDKDQTRRVLYDQHEVDRRLYKAMTRDESLTLPVRLQVQRLFETEMPRDSAPSRIVDRCVLTGRVRGLVKFAGLSRIMLRQLIHYGHIGGVAKASW 8a22 Bo 2.91 BS01 rna B3 0 R17 R19 I20 R36 H37 A39 V41 S42 R47 L61 R73 N80 R83 R84 I85 L89 H92 X115 X151 R17 R19 I20 R36 H37 A39 V41 S42 R47 L61 R73 N80 R83 R84 I85 L89 H92 X115 X151 0003735,0005840,0006412 36253367 13 ~ 391 QNAKAHLVEKFLGPEFRPRIKQLKAKRLEAVNDIKRHEADVSSPEVRVSLMTYRIRDSIPLFDECKKELTGMRKLEIMFNKRRRILRGLRKHNFPIYSMIINKLGMRDIYSDPGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 8a22 Bp 2.91 BS01 rna B2 0 M19 K28 H29 K35 L36 N42 K43 R54 R55 R58 S60 G61 T100 P119 P120 K123 A129 K132 W133 P135 M1 K10 H11 K17 L18 N24 K25 R36 R37 R40 S42 G43 T82 P101 P102 K105 A111 K114 W115 P117 0003735,0005840,0006412 36253367 1 ~ 214 MNNLLTQLPKHDLLKIKLVRWGFNKKPFYVLSVMKRRQARNSGNRYEDIGWWDPSPHQDGNSHFGIKFDRVKYWLSQGAVPTEKVYGLFGQAGIIPQKPAPPKYKPADGNADTKWRPELQKNL 8a22 Bq 2.91 BS01 rna B1 0 G4 F6 Q63 G1 F3 Q60 0003735,0005840,0006412 36253367 1 ~ 102 GGFEFVGKVVSNRMQKGVVVAVNYVVWIPKYKVYERRTARHMAHDEGNSCVIGDIVRIQQHRKLSKNKAYVVVSTLKHADVYNAKQAAVLNTERSQNKLGRVEYAESRLSEVQQRLLKLREMYQKELALN 8a22 Bq 2.91 BS02 rna B2 0 S14 R16 M17 Q18 Y27 K35 R40 R43 R65 K66 K69 N70 K71 S11 R13 M14 Q15 Y24 K32 R37 R40 R62 K63 K66 N67 K68 0003735,0005840,0006412 36253367 1 ~ 214 GGFEFVGKVVSNRMQKGVVVAVNYVVWIPKYKVYERRTARHMAHDEGNSCVIGDIVRIQQHRKLSKNKAYVVVSTLKHADVYNAKQAAVLNTERSQNKLGRVEYAESRLSEVQQRLLKLREMYQKELALN 8a22 Bq 2.91 BS03 rna B3 0 K33 K35 R39 R104 Y107 R111 K30 K32 R36 R101 Y104 R108 0003735,0005840,0006412 36253367 13 ~ 391 GGFEFVGKVVSNRMQKGVVVAVNYVVWIPKYKVYERRTARHMAHDEGNSCVIGDIVRIQQHRKLSKNKAYVVVSTLKHADVYNAKQAAVLNTERSQNKLGRVEYAESRLSEVQQRLLKLREMYQKELALN 8a22 Br 2.91 BS01 rna B3 0 R38 I39 Q52 K60 R63 N64 G70 R31 I32 Q45 K53 R56 N57 G63 0003735,0005840,0006412 36253367 13 ~ 391 FRPRSTHQEVTEMADFKNVSFLTQFLSPAGRIQPRRVTKLTEPLQRRIAKSVKLARNMALMAGEARLDKLHLTRVRQEELHRYQLKKSVQ 8a22 Bs 2.91 BS01 rna B3 0 G71 R72 T94 G66 R67 T89 0003723,0003735,0005840,0006412 36253367 13 ~ 391 GRAVWRGPYVSVSLLEQVITFAKRNPEWWNIGRFQGSKAPEAINTFCRSSTVLPDFLGLKFGVHNGREFVGVEVQEAMVGHKLGEFSQTTFR 8a22 Bs 2.91 BS02 rna B4 0 G6 R7 V9 W10 Y14 F51 R53 G71 K87 E90 T94 R97 G1 R2 V4 W5 Y9 F46 R48 G66 K82 E85 T89 R92 0003723,0003735,0005840,0006412 36253367 2 ~ 349 GRAVWRGPYVSVSLLEQVITFAKRNPEWWNIGRFQGSKAPEAINTFCRSSTVLPDFLGLKFGVHNGREFVGVEVQEAMVGHKLGEFSQTTFR 8a22 Bt 2.91 BS01 rna B4 0 R55 P56 S57 F61 A69 M72 G73 I76 H77 R39 P40 S41 F45 A53 M56 G57 I60 H61 0003735,0005840,0006412 36253367 2 ~ 349 AFVAEVRDGNVDAALAQVKKYRKTEGVNDSVRKKEYFLRPSLQKFRDSELTYAKNMGKLIHERVNWVVKRKKIKL 8a22 Bu 2.91 BS01 peptide Ui 0 E167 H170 A174 Y177 E153 H156 A160 Y163 36253367 1 ~ 26 AFSRYFVQKFKQSYTRKYMRDMESGAFSFPKCHDILGKYRPDVLFAAAAAPLKLELPEQAVYKKLYRDFPELRKDAVDLSSLEAPLAKQFALKHLVLSAEIAANSPRTRHILRRDLEADPAYERLKEEFMPRIAELRKQQEQTASLQQLQADEEEHLKLALTYVAAQ 8a22 Bv 2.91 BS01 rna B2 0 R65 R76 Q83 R84 F86 I87 Y101 R1 R12 Q19 R20 F22 I23 Y37 36253367 1 ~ 214 RVFTSNKMDEERAKRITEQRDFIQARVEWKKATISLYKEWRRTFLQKDIEEQHTKEVAAEQAKVAFAEQKAAAEHVRRQAALEELLRKTEIECQLAMVRVGRAQKAEETGRLIKKAENLRYAMLLEESRNWIDSEEELEKRINQSLENPEAFGFIVDLPIAKGL 8a22 Bv 2.91 BS02 rna B3 0 R163 T173 R99 T109 36253367 13 ~ 391 RVFTSNKMDEERAKRITEQRDFIQARVEWKKATISLYKEWRRTFLQKDIEEQHTKEVAAEQAKVAFAEQKAAAEHVRRQAALEELLRKTEIECQLAMVRVGRAQKAEETGRLIKKAENLRYAMLLEESRNWIDSEEELEKRINQSLENPEAFGFIVDLPIAKGL 8a22 Bw 2.91 BS01 rna B4 0 R175 F245 R249 Q343 H344 Q355 S393 I394 R395 F453 R54 F124 R128 Q222 H223 Q234 S272 I273 R274 F332 36253367 2 ~ 349 SKILVEKRSPELTQEHIGNYYKVTTERVPEGFMPFHQAFYAKPDAGQERKGGCRGIQHEFDISGHHNVMLRSSTLELFDLIKEGDKNRILLSGPTGTGKSVALFSLVEWARQQDWIVLYIPSAFTLTRGGFFYRRPGTDLFDTLTSAQHLLKGLLDCHQAQLAKLPLSSDDSKLLELVQKGLLNDDAHTAVDCCLEVVKELSLAAATQPVLFAIDGYNALFQHTDYGVTEGDIQVARRRLLKVEELTLANSMRLLERADLGKARVVVAPSWSIRSSLQVGKPVETTEFVMPRFDFAETANALYYYQCCGLAPDVPTEKQAKLMQHITNGNAFEIRSLAIKMSMLKLNKL 8a22 Bw 2.91 BS02 ATP Bw 1 G176 E180 M190 T218 G219 K220 S221 V222 S391 W392 S393 R456 G55 E59 M69 T97 G98 K99 S100 V101 S270 W271 S272 R335 36253367 502 SKILVEKRSPELTQEHIGNYYKVTTERVPEGFMPFHQAFYAKPDAGQERKGGCRGIQHEFDISGHHNVMLRSSTLELFDLIKEGDKNRILLSGPTGTGKSVALFSLVEWARQQDWIVLYIPSAFTLTRGGFFYRRPGTDLFDTLTSAQHLLKGLLDCHQAQLAKLPLSSDDSKLLELVQKGLLNDDAHTAVDCCLEVVKELSLAAATQPVLFAIDGYNALFQHTDYGVTEGDIQVARRRLLKVEELTLANSMRLLERADLGKARVVVAPSWSIRSSLQVGKPVETTEFVMPRFDFAETANALYYYQCCGLAPDVPTEKQAKLMQHITNGNAFEIRSLAIKMSMLKLNKL 8a22 By 2.91 BS01 rna B4 0 R111 H120 Y122 A123 R55 H64 Y66 A67 36253367 2 ~ 349 SYIPPSEVPEEHLKNIYEGIFGSPVAEFERTGRCALAKPLIGTKLSSYYFLPPNRQPGFHNEEHEYAKVRLMSKRQKK 8a22 Bz 2.91 BS01 rna B1 0 S54 K96 W121 Y123 S15 K57 W82 Y84 0003735,0005739 36253367 1 ~ 102 SYLAQLVPRDKRTLSNVILNLPNHGIGGIFARDTWHPESKRYWEILEVVTAKDSSAKVDAYGYLYYQGEKTHPFPKRVHSVWRYGWYWKPKPEQEKLLQPLKERYNTLVDMGIIDPSQL 8a22 Bz 2.91 BS02 rna B2 0 H75 S78 R80 Y105 Q106 F113 H118 H36 S39 R41 Y66 Q67 F74 H79 0003735,0005739 36253367 1 ~ 214 SYLAQLVPRDKRTLSNVILNLPNHGIGGIFARDTWHPESKRYWEILEVVTAKDSSAKVDAYGYLYYQGEKTHPFPKRVHSVWRYGWYWKPKPEQEKLLQPLKERYNTLVDMGIIDPSQL 8a22 Xa 2.91 BS01 rna A9 0 K71 T72 V76 K78 E98 N99 L102 K104 K105 F106 M135 S138 R145 K149 K19 T20 V24 K26 E46 N47 L50 K52 K53 F54 M83 S86 R93 K97 36253367 51 ~ 129 IEEYYVVPPACPPPPHNPKTLKYVPKLNRTQIIARVYEAKTPTELENSALGKKFFSEFAAVAKLVRLSQLRRANVYNSRDDAMCVSIYNTSVRVADKLLHLSSDEELCGLIWALSQLPYPEYENLVDRSLQILLEEDKPLKTGSSLAVSRAAAGLASLGRWDASTWEVLVPLLRKNVQEGKEVELSNLALGLYDARETV 8a22 Xb 2.91 BS01 rna A6 0 Y118 Y143 W144 Y103 Y128 W129 36253367 1 ~ 132 ITTLEFYEQNKEKLSFLVGNDVYSEFEEKWKPKPKVFDPEIPIAEAMWPEGRSEKLQSVIVKKLSFSTESAGSVVAGMKHGYCPDSVDVIVSRVEQLKAFEGYFPGFKTEEFVSVNPRLLNFSTDRIYWAMLTFQDMFSSAEVGPLMANIGHFIIENPIRCAKNLFCLATELESQLSMKLDVTAVKQDSWFTLSSEETIRERVAALATIFGSKTAGDILLRDINYLRLDSKDVNRDAVKIREHF 8a22 Xc 2.91 BS01 rna A7 0 R37 K38 N63 R1 K2 N27 36253367 1 ~ 576 RKNIVWPEQLEEQKRNKQYEYQWVISNGKKFIARRESTSTKWEIWKSIEKVTPGQKP 8a22 Xd 2.91 BS01 rna A1 0 S98 R101 I120 K128 H134 R136 R143 W148 G151 K153 F155 Q157 R164 H166 R192 W199 A238 D239 Q242 E290 W296 Q365 L369 W406 S36 R39 I58 K66 H72 R74 R81 W86 G89 K91 F93 Q95 R102 H104 R130 W137 A176 D177 Q180 E228 W234 Q303 L307 W344 36253367 1 ~ 109 YRNKVTIEYIKLKEPENDDYATRDPTNYAQLLGAISISRHLDRTTYLYETFKDKFDTIHYVTALTKLPGLVHYRGADLVMRDGVQWSEGVKPFWQKPNAQPRKHLLPKAQGLLSKLEEQFPPHLNNLFPRQTANLIWAYGQLKRKQVVAACPFLGDFLLSLRRDNFLALDKHATGADYAQIVKGLANLQTAGSPADEDTRALIEDFVDQLTQEMLLRRGHARLLDAREAQSILWGLGKLNRRKNTAIIDVLCDVVLAGVNSLTPTALAGAFSALAKLGHSSRTDVFEAMAKGYHLQTTLMSPQDVSLTVCACADLGFRDDNLLKICGLKAADMLGEFSNASLAWLMAGFGRLGYNHEAFFSAVNKSVLAEPVVEVEPGFAWRVLSAYAGSGRKDSESLKVCGRITEAFLAKLY 8a22 Xd 2.91 BS02 rna A7 0 Y63 N65 Y1 N3 36253367 1 ~ 576 YRNKVTIEYIKLKEPENDDYATRDPTNYAQLLGAISISRHLDRTTYLYETFKDKFDTIHYVTALTKLPGLVHYRGADLVMRDGVQWSEGVKPFWQKPNAQPRKHLLPKAQGLLSKLEEQFPPHLNNLFPRQTANLIWAYGQLKRKQVVAACPFLGDFLLSLRRDNFLALDKHATGADYAQIVKGLANLQTAGSPADEDTRALIEDFVDQLTQEMLLRRGHARLLDAREAQSILWGLGKLNRRKNTAIIDVLCDVVLAGVNSLTPTALAGAFSALAKLGHSSRTDVFEAMAKGYHLQTTLMSPQDVSLTVCACADLGFRDDNLLKICGLKAADMLGEFSNASLAWLMAGFGRLGYNHEAFFSAVNKSVLAEPVVEVEPGFAWRVLSAYAGSGRKDSESLKVCGRITEAFLAKLY 8a22 Xe 2.91 BS01 rna A3 0 Q238 K242 K349 T350 R352 H358 F359 R361 K362 R364 S366 S367 L369 Q169 K173 K280 T281 R283 H289 F290 R292 K293 R295 S297 S298 L300 36253367 1 ~ 210 FHTGVNLVQPIDTSKLTRQIKKLTLLHEAALTVLQYSNYCNPEQATEILRRLPFLMRHEESRVLKGQTLDPKLPPMFHGLLHVMGDRFVQVFSDCNLRQIERGAWALAAARHQHDGVALALSEKLKQLTQELLDLNAKPFNTRVTKPTPEQLNSGIFASRVLVPESVNQLPVKAVLPEFNALAGIAWALATVAGEHSAAAAKAALEQLAEKFGALQVDPKPLPDADSLCRLAWAFAKAGVHNPAAVDKLFHLAEERLKSQLQAHDPASGPLRPRCTYRYKTVRGWVDQHFPRKPRDSSYLGDTAPKIIPRDFEIDSLGSLLSAAALLRDQVPVERLQTILNLAAQHTAASSVAGGALQPLMVTYEEVTRVLAACEQLGFRSSTLVTPLLHGLPMAALSAEALSQLAAAATLHHVRSRTVYLRIVRAFNAKLSVSPTLVAGAGIGAEGKKEGEAAAALGAQLLLAVTKAGLPANASVSRIASLV 8a22 Xe 2.91 BS02 rna A6 0 K134 G513 K521 K65 G440 K448 36253367 1 ~ 132 FHTGVNLVQPIDTSKLTRQIKKLTLLHEAALTVLQYSNYCNPEQATEILRRLPFLMRHEESRVLKGQTLDPKLPPMFHGLLHVMGDRFVQVFSDCNLRQIERGAWALAAARHQHDGVALALSEKLKQLTQELLDLNAKPFNTRVTKPTPEQLNSGIFASRVLVPESVNQLPVKAVLPEFNALAGIAWALATVAGEHSAAAAKAALEQLAEKFGALQVDPKPLPDADSLCRLAWAFAKAGVHNPAAVDKLFHLAEERLKSQLQAHDPASGPLRPRCTYRYKTVRGWVDQHFPRKPRDSSYLGDTAPKIIPRDFEIDSLGSLLSAAALLRDQVPVERLQTILNLAAQHTAASSVAGGALQPLMVTYEEVTRVLAACEQLGFRSSTLVTPLLHGLPMAALSAEALSQLAAAATLHHVRSRTVYLRIVRAFNAKLSVSPTLVAGAGIGAEGKKEGEAAAALGAQLLLAVTKAGLPANASVSRIASLV 8a22 Xe 2.91 BS03 rna A7 0 F70 H71 T72 R229 F1 H2 T3 R160 36253367 1 ~ 576 FHTGVNLVQPIDTSKLTRQIKKLTLLHEAALTVLQYSNYCNPEQATEILRRLPFLMRHEESRVLKGQTLDPKLPPMFHGLLHVMGDRFVQVFSDCNLRQIERGAWALAAARHQHDGVALALSEKLKQLTQELLDLNAKPFNTRVTKPTPEQLNSGIFASRVLVPESVNQLPVKAVLPEFNALAGIAWALATVAGEHSAAAAKAALEQLAEKFGALQVDPKPLPDADSLCRLAWAFAKAGVHNPAAVDKLFHLAEERLKSQLQAHDPASGPLRPRCTYRYKTVRGWVDQHFPRKPRDSSYLGDTAPKIIPRDFEIDSLGSLLSAAALLRDQVPVERLQTILNLAAQHTAASSVAGGALQPLMVTYEEVTRVLAACEQLGFRSSTLVTPLLHGLPMAALSAEALSQLAAAATLHHVRSRTVYLRIVRAFNAKLSVSPTLVAGAGIGAEGKKEGEAAAALGAQLLLAVTKAGLPANASVSRIASLV 8a22 Xf 2.91 BS01 rna A3 0 K190 F193 R195 R197 T198 S199 K200 P202 K162 F165 R167 R169 T170 S171 K172 P174 36253367 1 ~ 210 RPALTPSFSRVSDPWTGEKEAKYAAPYRIPEEVWKNSGAPKILFQDPWNSPDYDEVRKKHAVLVHDYLKQQSQPINVQTILEGVNKTHGLVLGTIEYVTSLLENMLWHDMAYVVKPVFSSPRKAKLSKIPLLYGANKYQQVFRGTPKEVAERYEAARAKHIKVAFTRLRTSKTPQPFRRRTDEYSHVQASQSALGLAAAAA 8a22 Xg 2.91 BS01 rna A1 0 K40 W48 Y60 K61 V62 N64 I65 F72 K79 H84 M88 H89 N99 Y111 G113 S115 F116 T117 R119 S126 L127 Y129 K206 V208 H227 W229 N238 R246 V268 L272 S275 L359 D363 K16 W24 Y36 K37 V38 N40 I41 F48 K55 H60 M64 H65 N75 Y87 G89 S91 F92 T93 R95 S102 L103 Y105 K135 V137 H156 W158 N167 R175 V197 L201 S204 L288 D292 36253367 1 ~ 109 SVKYIPNHAATPNKYKDAQQKVLWDRAKKLGKKPEYKVPNIKDTQTVFEIGKLTKLCLEHWKPMHFAAALGHVINVWTTQALKSGRYGGKSFTVRELLGFRSLPYGVNSITAVLPLQSPEDFLSQPLAKQPFSFKPVSVREEVKKIIASNPGLLIHNWSLKIEGQPNHPITDEDRAAAVIAICTSSFRARFNEAGDVAVALVLSRLARCGYWLPPLYELIAPFAAFQGARIDHSSPAVIANVLLVLARAKGQAEMGQPTALQIRAIAPALEQKCLQRLGELLPSLEALVISDTLAATALLSSPEARALLAQIKAEVLARNFLGFESRDIIACFKELVANVYQPLQLSADLPAPGELRDELPGGEKVLDEQLLAALSGAVVEGGALAAAAAAAAAAAAAAAAAAAAAAAAA 8a22 Xg 2.91 BS02 rna A7 0 S25 V26 K27 Y28 I29 P30 H32 P36 N37 S1 V2 K3 Y4 I5 P6 H8 P12 N13 36253367 1 ~ 576 SVKYIPNHAATPNKYKDAQQKVLWDRAKKLGKKPEYKVPNIKDTQTVFEIGKLTKLCLEHWKPMHFAAALGHVINVWTTQALKSGRYGGKSFTVRELLGFRSLPYGVNSITAVLPLQSPEDFLSQPLAKQPFSFKPVSVREEVKKIIASNPGLLIHNWSLKIEGQPNHPITDEDRAAAVIAICTSSFRARFNEAGDVAVALVLSRLARCGYWLPPLYELIAPFAAFQGARIDHSSPAVIANVLLVLARAKGQAEMGQPTALQIRAIAPALEQKCLQRLGELLPSLEALVISDTLAATALLSSPEARALLAQIKAEVLARNFLGFESRDIIACFKELVANVYQPLQLSADLPAPGELRDELPGGEKVLDEQLLAALSGAVVEGGALAAAAAAAAAAAAAAAAAAAAAAAAA 8a22 Ya 2.91 BS01 rna B1 0 R265 H269 S272 G299 E300 R144 H148 S151 G178 E179 36253367 1 ~ 102 ADLVRHLQSSGSKLQKLANLTSASCSYRDISVSLFGLQARQLGCTKPFVYTFSASEQAQSKSKPFDGKLRLPDVSQLSDTITVSGDAAPATLNLDQKYMDKISCWTQTIPSHLEMSYQNLTSVKLFPPVDASYPTYVDFEHATRLLDHFTSRKRLNYQRKMIKKRDKFQIKSWDHHAGEA 8a22 Ya 2.91 BS02 rna B2 0 R273 K274 K281 H296 H297 A298 R152 K153 K160 H175 H176 A177 36253367 1 ~ 214 ADLVRHLQSSGSKLQKLANLTSASCSYRDISVSLFGLQARQLGCTKPFVYTFSASEQAQSKSKPFDGKLRLPDVSQLSDTITVSGDAAPATLNLDQKYMDKISCWTQTIPSHLEMSYQNLTSVKLFPPVDASYPTYVDFEHATRLLDHFTSRKRLNYQRKMIKKRDKFQIKSWDHHAGEA 8a22 Yd 2.91 BS01 rna B2 0 T53 R54 R55 R56 L58 T2 R3 R4 R5 L7 36253367 1 ~ 214 TTRRRKLLGSRYGARLAKKNRQQFERARVILDCYSDEELRPDSPPVAVKEVTINTLQTMRFLFPQTSKEHLDIKQNIASYKIFSLNRELLSLLPK 8a22 Ye 2.91 BS01 rna B4 0 G4 R5 H6 G1 R2 H3 36253367 2 ~ 349 GRHLLPATAIRVRLNRGFESAWYTDVSYREMIKKDFLLAKLASSFVNRSSRASLRQIFPGGKDFPNFRTSRIFMQHLPYKSYASTFSYVAPKDGPQAKYGLFQSKL 8a22 Yl 2.91 BS01 rna B4 0 K52 G55 L57 G61 K63 T65 K46 G49 L51 G55 K57 T59 36253367 2 ~ 349 TVVLAPSKYDSQLKIPLKPTEMDEFEELRSFVDISIEKEADYVMNKFVGRLIKGGEKATAQQVLLRTLLHTRRLMQEGNITSLK