7qea A 2.28 BS01 B9I A 1 R136 N186 Y258 R272 K318 H319 H333 Y369 T416 D421 R422 G448 R97 N147 Y210 R224 K270 H271 H285 Y321 T368 D373 R374 G400 0004553,0005975 35799064 801 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYED 7qea A 2.28 BS02 ZN A 1 Q759 D760 R763 Q711 D712 R715 0004553,0005975 35799064 802 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYED 7qea A 2.28 BS03 ZN A 2 L330 G337 A339 L282 G289 A291 0004553,0005975 35799064 805 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYED 7qea A 2.28 BS04 ZN A 3 H274 R703 H226 R655 0004553,0005975 35799064 810 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYED 7qea A 2.28 BS05 ZN A 4 D61 N63 N65 E72 D22 N24 N26 E33 0004553,0005975 35799064 813 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYED 7qea A 2.28 BS06 ZN A 5 H603 E672 H555 E624 0004553,0005975 35799064 818 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYED 7qea B 2.28 BS01 B9I B 1 R136 N186 Y258 R272 K318 H319 H333 Y369 T416 R651 F652 R97 N147 Y211 R225 K271 H272 H286 Y322 T369 R604 F605 0004553,0005975 35799064 801 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYEDD 7qea B 2.28 BS02 ZN B 1 R434 E640 R387 E593 0004553,0005975 35799064 811 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYEDD 7qea B 2.28 BS03 ZN B 2 D61 N63 N65 D69 E72 D22 N24 N26 D30 E33 0004553,0005975 35799064 814 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYEDD 7qea B 2.28 BS04 ZN B 3 Q759 D760 R763 Q712 D713 R716 0004553,0005975 35799064 815 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYEDD 7qea B 2.28 BS05 ZN B 4 L330 G337 A339 L283 G290 A292 0004553,0005975 35799064 817 EQPELEARVKEIIEVDGYQFRDLNDNGELDPYEDWRLPTPERVADLVGQMSLVEKSGLMLINTLNAACDPQTGEFGVLPAQADNYINTQHMHRFVFRNVVDVRAEGVECTGTGTPVVSPAEAATFTNAVQEMSEATRLGIPSLFKSNARNHIDPAAGAFSAFPKEAGIAAAALGEQARRTGEATTGDMSVVADFADVMGEEWASIGLRGMYGYMADLSTEPRWYRTHETFTEDAYLAAEIMETLVQTLQGEELTDNGLALSPQTRVALTLKHFPGGGPQELGLDPHYAFGKAQVYPAGRFEEHFLPFQAAIDAGVSSIMPYYGVPVDVPVVGGEPGETYPHTGFAFSDSIVNGLLRDQLGFTGYVNSATGIINDRAWGLEGNTVPERVAAAINGGTDTLSGFSDVSVITDLYEADLISEERIDLAAERLLEPLFDMGLFENPYVDPDVATATVGADDHRAVGLDLQRKSLVLLQNEETDEGPVLPLKEGGDVYILGDFTEETVESYGYEVTNGNVAEGEERPSAAGSDYVLISMTAKTNAGDYVSDDPSLGLNPDHGTNPSVIIGDDGEPLPGLDGQSLWGAADVCVHKEGHEENPSCTDNRLRFGGAYPWESSILDFTGMEAAESWEVVPSLETIQEVMAEVEDPSKVILHVYFRQPYVLDEESGLRDAGAILAGFGMTDTALMDVLTGAYAPQGKLPFALAGTREAIIEQDSDRPGYDETEDGALYPFGYGLTYEDD