7neq A 3.12 BS01 U9N A 1 I543 C544 I455 C456 7.6.2.2 0005515,0005524,0005654,0005739,0005886,0006869,0008514,0008559,0015143,0015225,0015562,0015711,0015747,0015878,0016020,0016324,0016887,0030148,0031526,0031966,0032217,0032218,0042626,0042802,0042803,0042910,0045121,0046415,0046624,0046983,0055085,0070633,0097744,0098591,0140115,0140359,0150104,1990748,1990962 Q9UNQ0 33838147 1002 AVLSFHNICYRVKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 7neq A 3.12 BS02 CLR A 1 L641 Y645 L553 Y557 7.6.2.2 0005515,0005524,0005654,0005739,0005886,0006869,0008514,0008559,0015143,0015225,0015562,0015711,0015747,0015878,0016020,0016324,0016887,0030148,0031526,0031966,0032217,0032218,0042626,0042802,0042803,0042910,0045121,0046415,0046624,0046983,0055085,0070633,0097744,0098591,0140115,0140359,0150104,1990748,1990962 Q9UNQ0 33838147 1003 AVLSFHNICYRVKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 7neq A 3.12 BS03 R1H B 1 F432 T435 N436 F439 V442 T542 M549 F344 T347 N348 F351 V354 T454 M461 7.6.2.2 0005515,0005524,0005654,0005739,0005886,0006869,0008514,0008559,0015143,0015225,0015562,0015711,0015747,0015878,0016020,0016324,0016887,0030148,0031526,0031966,0032217,0032218,0042626,0042802,0042803,0042910,0045121,0046415,0046624,0046983,0055085,0070633,0097744,0098591,0140115,0140359,0150104,1990748,1990962 IC50=526nM, EC50=100nM Q9UNQ0 33838147 1101 AVLSFHNICYRVKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 7neq B 3.12 BS01 R1H B 1 N436 F439 V546 M549 N348 F351 V458 M461 7.6.2.2 0005515,0005524,0005654,0005739,0005886,0006869,0008514,0008559,0015143,0015225,0015562,0015711,0015747,0015878,0016020,0016324,0016887,0030148,0031526,0031966,0032217,0032218,0042626,0042802,0042803,0042910,0045121,0046415,0046624,0046983,0055085,0070633,0097744,0098591,0140115,0140359,0150104,1990748,1990962 IC50=526nM, EC50=100nM Q9UNQ0 33838147 1101 AVLSFHNICYRVKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY