7nel A 1.45 BS01 peptide C 0 I358 K362 L372 V376 E380 D538 L539 E542 I54 K58 L68 V72 E76 D232 L233 E236 ? P03372 34006920 687 ~ 698 SLALSLTADQIISALLEAEPPILYSEYDPSRPFSEAYMMGLLTNLADRELVHMINWAKKVPGFVDLSLHDQVHLLESAWLEILMIGLVWRSMDHPGKLLFAPDLLLDREQGKSVEGMVEIFDMLLATSERFREMKLQREEFVCLKAIILLNSGVYTFSTLKSLENKEKIHRMLDKITDALIWYMAKSGLSLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVVPLSDLLLEMLDAHR 7nel A 1.45 BS02 EST A 1 E353 F404 H524 L525 E49 F100 H218 L219 ? IC50=1.3nM, Kd=0.2nM, EC50=0.75nM, Ki=0.21nM P03372 34006920 601 SLALSLTADQIISALLEAEPPILYSEYDPSRPFSEAYMMGLLTNLADRELVHMINWAKKVPGFVDLSLHDQVHLLESAWLEILMIGLVWRSMDHPGKLLFAPDLLLDREQGKSVEGMVEIFDMLLATSERFREMKLQREEFVCLKAIILLNSGVYTFSTLKSLENKEKIHRMLDKITDALIWYMAKSGLSLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVVPLSDLLLEMLDAHR 7nel B 1.45 BS01 peptide D 0 I358 K362 L372 V376 E380 D538 L539 E542 M543 I55 K59 L69 V73 E77 D235 L236 E239 M240 ? P03372 34006920 686 ~ 696 NSLALSLTADQIISALLEAEPPILYSEYDPSRPFSEAYMMGLLTNLADRELVHMINWAKKVPGFVDLSLHDQVHLLESAWLEILMIGLVWRSMDHPGKLLFAPDLLLDREQGKSVEGMVEIFDMLLATSERFREMKLQREEFVCLKAIILLNSGVYTFLSSTLKSLENKEKIHRMLDKITDALIWYMAKSGLSLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVVPLSDLLLEMLDAHR 7nel B 1.45 BS02 EST B 1 E353 L387 F404 H524 L525 E50 L84 F101 H221 L222 ? IC50=1.3nM, Kd=0.2nM, EC50=0.75nM, Ki=0.21nM P03372 34006920 601 NSLALSLTADQIISALLEAEPPILYSEYDPSRPFSEAYMMGLLTNLADRELVHMINWAKKVPGFVDLSLHDQVHLLESAWLEILMIGLVWRSMDHPGKLLFAPDLLLDREQGKSVEGMVEIFDMLLATSERFREMKLQREEFVCLKAIILLNSGVYTFLSSTLKSLENKEKIHRMLDKITDALIWYMAKSGLSLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVVPLSDLLLEMLDAHR