7kk5 A 1.7 BS01 3JD A 1 Q759 D766 H862 G863 Y889 Y896 F897 S904 Y907 Q93 D100 H191 G192 Y218 Y225 F226 S233 Y236 S904 Y907 E988 S233 Y236 E317 2.4.2.-,2.4.2.30 0003950 IC50=132nM, Ki=3.2nM, EC50=31000nM P09874 33361107 9001 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQDSQILDLSNRFYTLIPHDFGKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 7kk5 B 1.7 BS01 3JD B 1 Q759 V762 D766 H862 G863 Y889 Y896 F897 K903 S904 Y907 E988 Q96 V99 D103 H195 G196 Y222 Y229 F230 K236 S237 Y240 E321 S904 Y907 E988 S237 Y240 E321 2.4.2.-,2.4.2.30 0003950 IC50=132nM, Ki=3.2nM, EC50=31000nM P09874 33361107 9001 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 7kk5 C 1.7 BS01 3JD C 1 Q759 V762 E763 D766 H862 G863 Y889 Y896 F897 K903 S904 Y907 Q93 V96 E97 D100 H196 G197 Y223 Y230 F231 K237 S238 Y241 S904 Y907 E988 S238 Y241 E322 2.4.2.-,2.4.2.30 0003950 IC50=132nM, Ki=3.2nM, EC50=31000nM P09874 33361107 9001 SKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 7kk5 D 1.7 BS01 3JD D 1 D766 H862 G863 Y889 Y896 F897 S904 Y907 D94 H184 G185 Y211 Y218 F219 S226 Y229 S904 Y907 E988 S226 Y229 E310 2.4.2.-,2.4.2.30 0003950 IC50=132nM, Ki=3.2nM, EC50=31000nM P09874 33361107 1103 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQILDLSNRFYTLIPHDPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK