6za4 A 2.092 BS01 M83 A 1 K205 I207 T361 Y385 L404 A418 G419 K438 K191 I193 T341 Y365 L384 A398 G399 K418 K205 E252 A269 E297 H334 T361 Y385 R405 G421 E434 K438 K191 E238 A255 E277 H314 T341 Y365 R385 G401 E414 K418 4.2.99.21,5.4.4.2,5.4.99.5 0000162,0000287,0004106,0005886,0008909,0009058,0009697,0010106,0016829,0016833,0016853,0019540,0043904,0046872,0052572 ic50=6.3uM P9WFX1 32530281 501 SSSIPMPAGVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVVITEPLAGGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVAR 6za4 B 2.092 BS01 M83 B 1 K205 I207 T361 Y385 L404 R405 A418 G419 K438 K207 I209 T335 Y359 L378 R379 A392 G393 K412 K205 E252 A269 E297 T361 Y385 R405 G421 E434 K438 K207 E254 A271 E278 T335 Y359 R379 G395 E408 K412 4.2.99.21,5.4.4.2,5.4.99.5 0000162,0000287,0004106,0005886,0008909,0009058,0009697,0010106,0016829,0016833,0016853,0019540,0043904,0046872,0052572 ic50=6.3uM P9WFX1 32530281 501 GHMSELSVATGAVSTASSSIPMPAGVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVVITEPLANSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVAR 6za4 C 2.092 BS01 M83 C 1 K205 I207 T361 Y385 L404 A418 G419 K438 K176 I178 T324 Y348 L367 A381 G382 K401 K205 E252 A269 E297 H334 T361 Y385 R405 G421 E434 K438 K176 E223 A240 E260 H297 T324 Y348 R368 G384 E397 K401 4.2.99.21,5.4.4.2,5.4.99.5 0000162,0000287,0004106,0005886,0008909,0009058,0009697,0010106,0016829,0016833,0016853,0019540,0043904,0046872,0052572 ic50=6.3uM P9WFX1 32530281 501 IPMPAGPADLAAELAAVEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDHREAIDRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVVITEPLAGTRALLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVAR 6za4 D 2.092 BS01 M83 D 1 K205 I207 T361 Y385 L404 R405 A418 G419 K438 K188 I190 T340 Y364 L383 R384 A397 G398 K417 K205 E252 A269 E297 H334 T361 Y385 R405 G421 E434 K438 K188 E235 A252 E276 H313 T340 Y364 R384 G400 E413 K417 4.2.99.21,5.4.4.2,5.4.99.5 0000162,0000287,0004106,0005886,0008909,0009058,0009697,0010106,0016829,0016833,0016853,0019540,0043904,0046872,0052572 ic50=6.3uM P9WFX1 32530281 501 SSIPMPVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVVITEPLAGTRAPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVAR