6yph A 1.67 BS01 N5Q A 1 L45 G46 R47 V66 K68 F113 M163 I174 D175 L44 G45 R46 V65 K67 F112 M162 I173 D174 D156 K158 N161 D175 S194 D155 K157 N160 D174 S193 2.7.11.1 0004672,0004674,0005524,0006468 IC50=600nM, Kd=110nM, Ki=180nM P68400 33119282 401 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 6yph B 1.67 BS01 N5Q B 1 L45 G46 R47 V53 V66 K68 F113 H160 M163 I174 D175 L44 G45 R46 V52 V65 K67 F112 H159 M162 I173 D174 D156 K158 N161 D175 S194 D155 K157 N160 D174 S193 2.7.11.1 0004672,0004674,0005524,0006468 IC50=600nM, Kd=110nM, Ki=180nM P68400 33119282 401 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV