6yid A 2.7 BS01 EDJ A 1 V15 V23 A37 M85 C88 G91 L138 V16 V24 A38 M86 C89 G92 L139 D131 K133 Q135 N136 D158 D132 K134 Q136 N137 D153 2.7.11.1 0004672,0004674,0005524,0006468,0010506 IC50=711nM Q8IYT8 33200929 301 SMEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANSGIRIKIADFGFARYLHSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQG 6yid B 2.7 BS01 EDJ B 1 V15 G16 V23 A37 K39 C88 G91 D92 V19 G20 V27 A41 K43 C92 G95 D96 D131 K133 Q135 N136 D158 S177 D135 K137 Q139 N140 D158 S168 2.7.11.1 0004672,0004674,0005524,0006468,0010506 IC50=711nM Q8IYT8 33200929 301 GGGSMEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANSVSGIRIKIADFGFARYLHSSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQ 6yid C 2.7 BS01 EDJ C 1 V15 V23 A37 C88 G91 V18 V26 A40 C91 G94 D131 K133 Q135 N136 D158 S177 D134 K136 Q138 N139 D154 S164 2.7.11.1 0004672,0004674,0005524,0006468,0010506 IC50=711nM Q8IYT8 33200929 301 GGSMEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANGIRIKIADFGFARYLHSSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLE 6yid D 2.7 BS01 EDJ D 1 V15 V23 A37 K39 C88 G91 V16 V24 A38 K40 C89 G92 D131 K133 Q135 N136 D158 D132 K134 Q136 N137 D151 2.7.11.1 0004672,0004674,0005524,0006468,0010506 IC50=711nM Q8IYT8 33200929 301 SMEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANIRIKIADFGFARYLHSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQG