6tw0 A 2.5 BS01 ZN A 1 D36 H38 D85 D11 H13 D60 D36 H38 D85 N117 H118 D121 H220 H243 N245 S350 R354 R395 D11 H13 D60 N92 H93 D96 H191 H214 N216 S321 R325 R362 3.1.3.35,3.1.3.5,3.1.3.89,3.1.3.91,3.1.3.99 0000166,0002953,0005515,0005654,0005829,0005886,0006196,0006259,0007159,0008252,0008253,0008270,0009166,0009897,0009986,0010035,0016020,0016787,0016788,0033198,0042802,0046032,0046034,0046086,0046872,0050340,0050483,0050484,0050728,0055074,0070062,0098552,0106411,0110148,0140928 P21589 32045236 601 MWELTILHTNDVHSRLEQTSEDSSKCVDASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKSQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLDSSIPEDPSIKADINKWRIKLDDYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHADNHVSMCILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSLE 6tw0 A 2.5 BS02 ZN A 2 D85 N117 H220 H243 D60 N92 H191 H214 D36 H38 D85 N117 H118 D121 H220 H243 N245 S350 R354 R395 D11 H13 D60 N92 H93 D96 H191 H214 N216 S321 R325 R362 3.1.3.35,3.1.3.5,3.1.3.89,3.1.3.91,3.1.3.99 0000166,0002953,0005515,0005654,0005829,0005886,0006196,0006259,0007159,0008252,0008253,0008270,0009166,0009897,0009986,0010035,0016020,0016787,0016788,0033198,0042802,0046032,0046034,0046086,0046872,0050340,0050483,0050484,0050728,0055074,0070062,0098552,0106411,0110148,0140928 P21589 32045236 602 MWELTILHTNDVHSRLEQTSEDSSKCVDASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKSQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLDSSIPEDPSIKADINKWRIKLDDYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHADNHVSMCILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSLE 6tw0 A 2.5 BS03 NYZ A 1 D85 H118 H243 R354 N390 G392 R395 G447 F500 D506 D60 H93 H214 R325 N357 G359 R362 G414 F467 D473 D36 H38 D85 N117 H118 D121 H220 H243 N245 S350 R354 R395 D11 H13 D60 N92 H93 D96 H191 H214 N216 S321 R325 R362 3.1.3.35,3.1.3.5,3.1.3.89,3.1.3.91,3.1.3.99 0000166,0002953,0005515,0005654,0005829,0005886,0006196,0006259,0007159,0008252,0008253,0008270,0009166,0009897,0009986,0010035,0016020,0016787,0016788,0033198,0042802,0046032,0046034,0046086,0046872,0050340,0050483,0050484,0050728,0055074,0070062,0098552,0106411,0110148,0140928 Ki=38.8nM P21589 32045236 603 MWELTILHTNDVHSRLEQTSEDSSKCVDASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKSQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLDSSIPEDPSIKADINKWRIKLDDYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHADNHVSMCILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSLE