6to7 A 2.26 BS01 SUV A 1 A102 S103 P123 Q126 V130 Q179 F219 I314 N318 H344 A58 S59 P79 Q82 V86 Q135 F175 I237 N241 H267 ? 0004930,0007186,0007631,0016020,0016499 IC50=50nM, Ki=0.600000nM O43613 31860301 401 YAWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFLVNLSLADVLATAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRALGSILGIWAVSLAIMVPQAAVMECSSVLPELAARTRAFSVCDERWADDLAPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRIPGTTSAEVKQMRARRKTAKMLMVVVLVFALCYLPISVLNVLKRVFGMFRQASDREAVYAAFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSWWL 6to7 A 2.26 BS02 PGW A 1 S138 W145 L230 M233 A234 Q237 S94 W101 L186 M189 A190 Q193 ? 0004930,0007186,0007631,0016020,0016499 O43613 31860301 426 YAWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFLVNLSLADVLATAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRALGSILGIWAVSLAIMVPQAAVMECSSVLPELAARTRAFSVCDERWADDLAPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRIPGTTSAEVKQMRARRKTAKMLMVVVLVFALCYLPISVLNVLKRVFGMFRQASDREAVYAAFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSWWL 6to7 A 2.26 BS03 PGW B 1 A181 I214 A137 I170 ? 0004930,0007186,0007631,0016020,0016499 O43613 31860301 426 YAWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFLVNLSLADVLATAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRALGSILGIWAVSLAIMVPQAAVMECSSVLPELAARTRAFSVCDERWADDLAPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRIPGTTSAEVKQMRARRKTAKMLMVVVLVFALCYLPISVLNVLKRVFGMFRQASDREAVYAAFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSWWL 6to7 B 2.26 BS01 PGW A 1 A174 V177 A181 A145 V148 A152 ? 0004930,0007186,0007631,0016020,0016499 O43613 31860301 426 EFLRYLWRDYLYPKQYAWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFLVNLSLADVLATAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRALGSILGIWAVSLAIMVPQAAVMECSSFSVCDERWADDLAPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGGTTSAEVKQMRARRKTAKMLMVVVLVFALCYLPISVLNVLKRVFGMFRQASDREAVYAAFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSWWLPGLAAA 6to7 B 2.26 BS02 SUV B 1 A102 S103 P123 Q126 V130 Q179 F219 I314 N318 H344 A73 S74 P94 Q97 V101 Q150 F179 I238 N242 H268 ? 0004930,0007186,0007631,0016020,0016499 IC50=50nM, Ki=0.600000nM O43613 31860301 401 EFLRYLWRDYLYPKQYAWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFLVNLSLADVLATAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRALGSILGIWAVSLAIMVPQAAVMECSSFSVCDERWADDLAPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGGTTSAEVKQMRARRKTAKMLMVVVLVFALCYLPISVLNVLKRVFGMFRQASDREAVYAAFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSWWLPGLAAA 6to7 B 2.26 BS03 PGW B 1 S138 G229 L230 M233 A234 Q237 S109 G189 L190 M193 A194 Q197 ? 0004930,0007186,0007631,0016020,0016499 O43613 31860301 426 EFLRYLWRDYLYPKQYAWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFLVNLSLADVLATAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRALGSILGIWAVSLAIMVPQAAVMECSSFSVCDERWADDLAPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGGTTSAEVKQMRARRKTAKMLMVVVLVFALCYLPISVLNVLKRVFGMFRQASDREAVYAAFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSWWLPGLAAA