6std A 1.8 BS01 CA A 1 E163 D164 E155 D156 Y30 D31 Y50 H85 H110 Y22 D23 Y42 H77 H102 4.2.1.94 0005575,0005768,0006582,0016829,0030411,0042438,0046872 P56221 10382670 501 GEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK 6std A 1.8 BS02 MS2 A 1 W26 Y50 F53 V75 L76 V108 N131 F162 G165 W18 Y42 F45 V67 L68 V100 N123 F154 G157 Y30 D31 Y50 H85 H110 Y22 D23 Y42 H77 H102 4.2.1.94 0005575,0005768,0006582,0016829,0030411,0042438,0046872 Ki=2.3nM -logKd/Ki=8.64, Ki=2.3nM P56221 10382670 601 GEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK 6std B 1.8 BS01 CA B 1 R51 D55 R43 D47 Y30 D31 Y50 H85 H110 Y22 D23 Y42 H77 H102 4.2.1.94 0005575,0005768,0006582,0016829,0030411,0042438,0046872 P56221 10382670 501 GEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK 6std B 1.8 BS02 MS2 B 1 W26 Y50 F53 V75 L76 V108 N131 P149 F162 G165 W18 Y42 F45 V67 L68 V100 N123 P141 F154 G157 Y30 D31 Y50 H85 H110 Y22 D23 Y42 H77 H102 4.2.1.94 0005575,0005768,0006582,0016829,0030411,0042438,0046872 Ki=2.3nM P56221 10382670 600 GEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK 6std C 1.8 BS01 CA C 1 R51 D55 R43 D47 Y30 D31 Y50 H85 H110 Y22 D23 Y42 H77 H102 4.2.1.94 0005575,0005768,0006582,0016829,0030411,0042438,0046872 P56221 10382670 501 GEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK 6std C 1.8 BS02 MS2 C 1 W26 Y50 F53 V75 L76 H85 V108 N131 F162 G165 R166 W18 Y42 F45 V67 L68 H77 V100 N123 F154 G157 R158 Y30 D31 Y50 H85 H110 Y22 D23 Y42 H77 H102 4.2.1.94 0005575,0005768,0006582,0016829,0030411,0042438,0046872 Ki=2.3nM P56221 10382670 602 GEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK