6pww A 4.4 BS01 dna P 0 R220 R272 R294 R203 R255 R277 ? 0000976,0005515,0005634,0005654,0005730,0006325,0006974,0035097,0042393,0043627,0044665,0044666,0045815,0048188,0071339 Q15291 31804488 1 ~ 146 DGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFKELDENVEYEERESEFDI 6pww C 4.4 BS01 SAH C 1 I3838 H3839 G3840 R3841 Y3883 R3903 F3904 I3905 N3906 H3907 Y3944 L3955 P3956 L3968 I25 H26 G27 R28 Y70 R90 F91 I92 N93 H94 Y131 L139 P140 L152 2.1.1.-,2.1.1.364 IC50=2300nM Q03164 31804488 4001 LPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGIVIRSILTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDKLPCNCGAKKCRKFLN 6pww C 4.4 BS02 ZN C 1 S3908 C3909 C3959 S95 C96 C143 2.1.1.-,2.1.1.364 Q03164 31804488 4002 LPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGIVIRSILTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDKLPCNCGAKKCRKFLN 6pww G 4.4 BS01 dna O 0 R40 Y41 P43 G44 T45 V46 A47 R49 R63 K64 L65 P66 R69 R83 R4 Y5 P7 G8 T9 V10 A11 R13 R27 K28 L29 P30 R33 R47 ? 0000786,0003677,0005515,0005634,0005654,0005694,0030527,0046982 P84233 31804488 2 ~ 147 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6pww G 4.4 BS02 dna P 0 R42 P43 R63 R72 R83 F84 Q85 R116 V117 T118 M120 R6 P7 R27 R36 R47 F48 Q49 R80 V81 T82 M84 ? 0000786,0003677,0005515,0005634,0005654,0005694,0030527,0046982 P84233 31804488 1 ~ 146 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6pww H 4.4 BS01 dna O 0 R35 R45 I46 R78 K79 T80 R16 R26 I27 R59 K60 T61 ? 0000786,0003677,0005515,0005634,0005694,0006334,0030527,0046982 P62799 31804488 2 ~ 147 KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6pww H 4.4 BS02 dna P 0 T30 P32 R36 T11 P13 R17 ? 0000786,0003677,0005515,0005634,0005694,0006334,0030527,0046982 P62799 31804488 1 ~ 146 KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6pww I 4.4 BS01 dna O 0 R29 R42 V43 G44 A45 K75 T76 R77 R18 R31 V32 G33 A34 K64 T65 R66 ? 0000786,0003677,0005634,0005694,0030527,0046982 P06897 31804488 2 ~ 147 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6pww I 4.4 BS02 dna P 0 A14 K15 T16 R17 R20 G28 R29 R32 R42 R77 A3 K4 T5 R6 R9 G17 R18 R21 R31 R66 ? 0000786,0003677,0005634,0005694,0030527,0046982 P06897 31804488 1 ~ 146 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6pww J 4.4 BS01 dna O 0 K31 I36 Y37 K3 I8 Y9 ? 0000786,0003677,0005515,0005634,0005694,0030527,0046982 P02281 31804488 2 ~ 147 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6pww J 4.4 BS02 dna P 0 T29 R30 Y39 I51 S52 S53 R83 S84 T85 T1 R2 Y11 I23 S24 S25 R55 S56 T57 ? 0000786,0003677,0005515,0005634,0005694,0030527,0046982 P02281 31804488 1 ~ 146 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6pww K 4.4 BS01 dna O 0 H39 Y41 R42 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 M120 H3 Y5 R6 T9 R27 R36 R47 F48 Q49 S50 R80 V81 T82 M84 ? 0000786,0003677,0005515,0005634,0005654,0005694,0030527,0046982 P84233 31804488 2 ~ 147 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6pww K 4.4 BS02 dna P 0 R40 Y41 P43 G44 V46 A47 R49 K56 R63 K64 L65 P66 R69 R83 R4 Y5 P7 G8 V10 A11 R13 K20 R27 K28 L29 P30 R33 R47 ? 0000786,0003677,0005515,0005634,0005654,0005694,0030527,0046982 P84233 31804488 1 ~ 146 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6pww L 4.4 BS01 dna O 0 T30 P32 R36 R45 T11 P13 R17 R26 ? 0000786,0003677,0005515,0005634,0005694,0006334,0030527,0046982 P62799 31804488 2 ~ 147 KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6pww L 4.4 BS02 dna P 0 R35 R45 I46 S47 R78 K79 T80 R16 R26 I27 S28 R59 K60 T61 ? 0000786,0003677,0005515,0005634,0005694,0006334,0030527,0046982 P62799 31804488 1 ~ 146 KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6pww M 4.4 BS01 dna O 0 A14 K15 T16 R17 R20 G28 R29 R32 R77 A3 K4 T5 R6 R9 G17 R18 R21 R66 ? 0000786,0003677,0005634,0005694,0030527,0046982 P06897 31804488 2 ~ 147 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6pww M 4.4 BS02 dna P 0 R29 R42 V43 G44 A45 K75 T76 R77 R18 R31 V32 G33 A34 K64 T65 R66 ? 0000786,0003677,0005634,0005694,0030527,0046982 P06897 31804488 1 ~ 146 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6pww N 4.4 BS01 dna O 0 T29 R30 Y39 I51 S52 S53 R83 S84 T85 T1 R2 Y11 I23 S24 S25 R55 S56 T57 ? 0000786,0003677,0005515,0005634,0005694,0030527,0046982 P02281 31804488 2 ~ 147 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6pww N 4.4 BS02 dna P 0 T29 R30 K31 I36 Y37 T1 R2 K3 I8 Y9 ? 0000786,0003677,0005515,0005634,0005694,0030527,0046982 P02281 31804488 1 ~ 146 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA