6pij A 2.9 BS01 rna 1 0 A8 Y9 R11 L39 L40 H71 Y101 K102 W143 Q225 F227 F262 K263 R283 R291 K343 M346 A7 Y8 R10 L38 L39 H70 Y100 K101 W142 Q224 F226 F261 K262 R282 R290 K342 M345 31853065 1 ~ 60 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKEAAAAAAAATQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQHKGD 6pij A 2.9 BS02 dna 2 0 Q67 G68 P70 H71 F227 A239 Q241 S243 Q66 G67 P69 H70 F226 A238 Q240 S242 31853065 31 ~ 57 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKEAAAAAAAATQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQHKGD 6pij B 2.9 BS01 rna 1 0 Y9 E10 R11 L39 L40 Q42 Y101 W143 Q225 F227 F262 K263 A266 R283 R291 G344 G345 M346 Y8 E9 R10 L38 L39 Q41 Y100 W142 Q224 F226 F251 K252 A255 R272 R280 G333 G334 M335 31853065 1 ~ 60 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQHK 6pij B 2.9 BS02 dna 2 0 T5 N6 S47 G68 N69 P70 H71 M346 K350 T4 N5 S46 G67 N68 P69 H70 M335 K339 31853065 31 ~ 57 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQHK 6pij C 2.9 BS01 rna 1 0 Y9 E10 R11 L39 L40 Y101 W143 Q225 F227 K230 F262 K263 A266 R283 R291 G344 G345 M346 Y8 E9 R10 L38 L39 Y100 W142 Q224 F226 K229 F253 K254 A257 R274 R282 G335 G336 M337 31853065 1 ~ 60 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKATQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQH 6pij C 2.9 BS02 dna 2 0 M43 Q67 G68 N69 P70 H71 F227 S243 M346 Q348 H349 M42 Q66 G67 N68 P69 H70 F226 S234 M337 Q339 H340 31853065 31 ~ 57 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKATQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQH 6pij D 2.9 BS01 rna 1 0 Y9 R11 L39 L40 H71 Y101 K102 K144 Q225 F227 F262 K263 A266 R283 R291 K343 G344 G345 M346 Y8 R10 L38 L39 H70 Y100 K101 K143 Q224 F226 F251 K252 A255 R272 R280 K332 G333 G334 M335 31853065 1 ~ 60 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQH 6pij D 2.9 BS02 dna 2 0 F227 K230 M346 F226 K229 M335 31853065 31 ~ 57 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQH 6pij E 2.9 BS01 rna 1 0 Y9 E10 R11 L39 L40 G41 Y101 W143 R222 Q225 V226 F227 Q247 F262 K263 A266 R283 R291 G344 G345 M346 Y8 E9 R10 L38 L39 G40 Y100 W142 R221 Q224 V225 F226 Q236 F251 K252 A255 R272 R280 G333 G334 M335 31853065 1 ~ 60 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQHK 6pij E 2.9 BS02 dna 2 0 M346 Q348 M335 Q337 31853065 31 ~ 57 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMEAKSLAYDVSGQPIKSATAEALAQGNPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKQNSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQHK 6pij F 2.9 BS01 rna 1 0 Y9 E10 R11 Y101 W143 R147 M220 R222 Q225 F227 R244 F262 K263 R283 R291 G344 G345 M346 Y8 E9 R10 Y74 W116 R120 M193 R195 Q198 F200 R205 F223 K224 R244 R252 G305 G306 M307 31853065 1 ~ 60 KLPTNLAYERSIDPSDVCFFVVWPDDRKTPLTYNSRTLLGQMPHQVDFCHVPYGASHIECSFSVSFSSELRQPYKCNSSKVKQTLVQLVELYETKIGWTELATRYLMNICNGKWLWKNTRKAYCWNIVLTPWPWNGEKVGFEDIRTNYTSRQDFKNNKNWSAIVEMIKTAFSSTDGLAIFEVRATLHLPTNAMVRPSQVFTEKSRVFQSTTIDGERSPILGAFKTGAAIATIDDWYPEATEPLRVGRFGVHREDVTCYRHPSTGKDFFSILQQAEHYIEVLSANKTPAQETINDMHFLMANLIKGGMFQH 6pij G 2.9 BS01 rna 1 0 F92 T202 Q203 I204 S205 Y213 P218 V219 A220 S414 T416 A417 F421 H423 R427 T456 E458 R506 L507 A508 R509 Y573 L586 R587 Y589 F76 T186 Q187 I188 S189 Y197 P202 V203 A204 S291 T293 A294 F298 H300 R304 T333 E335 R383 L384 A385 R386 Y450 L463 R464 Y466 31853065 1 ~ 60 LKEIIASNPDDLTTELKRAFRPLTPHIAIDGNEIDALTILVNLTDKAKCKQKLRDEKWWASCINCVNYRQSHNPKFPDIRSEGVIRTQALGELPSFLLSSSKIPPYHWSYSHDSKYVNKSAFLTNEFCWDGEISCLGELLKDADHPLWNTLKKLGCSQKTCKAMAKQLADITLTTINVTLAPNYLTQISLPDSDTSYISLSPVASLSMQSHFHQRLQDENRHSAITRFSRTTNMGVTAMTCGGAFRMLKSGAKFSSPPHHRLNNGSFLVLPNIRVCGATALSSPVTVGIPSLTAFFGFVHAFERNINRTTSSFRVESFAICVHQLHVEKRGLTAEFVEKGDGTISAPATRDDWQCDVVFSLILNTNFAQHIDQDTLVTSLPKRLARGSAKIAIDDFKHINSFSTLETAIESLPIEAGRWLSLYAQSNNNLSDLLAAMTEDHQLMASCVGYHLLEEPKDKPNSLRGYKHAIAECIIGLINSITFSSETDPNTIFWSLKNYQNYLVVQPRSIN 6pij G 2.9 BS02 dna 2 0 K91 I95 H128 D129 K131 R246 N249 K462 A469 T472 K75 I79 H112 D113 K115 R230 N233 K339 A346 T349 31853065 31 ~ 57 LKEIIASNPDDLTTELKRAFRPLTPHIAIDGNEIDALTILVNLTDKAKCKQKLRDEKWWASCINCVNYRQSHNPKFPDIRSEGVIRTQALGELPSFLLSSSKIPPYHWSYSHDSKYVNKSAFLTNEFCWDGEISCLGELLKDADHPLWNTLKKLGCSQKTCKAMAKQLADITLTTINVTLAPNYLTQISLPDSDTSYISLSPVASLSMQSHFHQRLQDENRHSAITRFSRTTNMGVTAMTCGGAFRMLKSGAKFSSPPHHRLNNGSFLVLPNIRVCGATALSSPVTVGIPSLTAFFGFVHAFERNINRTTSSFRVESFAICVHQLHVEKRGLTAEFVEKGDGTISAPATRDDWQCDVVFSLILNTNFAQHIDQDTLVTSLPKRLARGSAKIAIDDFKHINSFSTLETAIESLPIEAGRWLSLYAQSNNNLSDLLAAMTEDHQLMASCVGYHLLEEPKDKPNSLRGYKHAIAECIIGLINSITFSSETDPNTIFWSLKNYQNYLVVQPRSIN 6pij G 2.9 BS03 dna 3 0 K23 R24 R27 K52 S130 K131 N134 M255 K17 R18 R21 K46 S114 K115 N118 M239 31853065 1 ~ 9 LKEIIASNPDDLTTELKRAFRPLTPHIAIDGNEIDALTILVNLTDKAKCKQKLRDEKWWASCINCVNYRQSHNPKFPDIRSEGVIRTQALGELPSFLLSSSKIPPYHWSYSHDSKYVNKSAFLTNEFCWDGEISCLGELLKDADHPLWNTLKKLGCSQKTCKAMAKQLADITLTTINVTLAPNYLTQISLPDSDTSYISLSPVASLSMQSHFHQRLQDENRHSAITRFSRTTNMGVTAMTCGGAFRMLKSGAKFSSPPHHRLNNGSFLVLPNIRVCGATALSSPVTVGIPSLTAFFGFVHAFERNINRTTSSFRVESFAICVHQLHVEKRGLTAEFVEKGDGTISAPATRDDWQCDVVFSLILNTNFAQHIDQDTLVTSLPKRLARGSAKIAIDDFKHINSFSTLETAIESLPIEAGRWLSLYAQSNNNLSDLLAAMTEDHQLMASCVGYHLLEEPKDKPNSLRGYKHAIAECIIGLINSITFSSETDPNTIFWSLKNYQNYLVVQPRSIN 6pij H 2.9 BS01 rna 1 0 H29 Y33 Q105 A113 R117 R120 R121 R125 S137 Y149 S151 S156 Q158 R161 N162 F163 R164 S183 Y184 N188 S189 H28 Y32 Q104 A112 R116 R119 R120 R124 S136 Y148 S150 S155 Q157 R160 N161 F162 R163 S182 Y183 N187 S188 0004519,0043571 31853065 1 ~ 60 KWYYKTITFLPELCNNESLAAKCLRVLHGFNYQYETRNIGVSFPLWCDATVGKKISFVSKNKIELDLLLKQHYFVQMEQLQYFHISNTVLVPEDCTYVSFRRCQSIDKLTAAGLARKIRRLEKRALSRGEAFDPSSFAQKEHTAIAHYHSLGESSKQTNRNFRLNIRMLSEQPREGNSIFSSYGLANSENSFQPVPL