6o2z A 2.5 BS01 LJV A 1 R109 A111 R119 W124 I128 I130 W267 D279 V281 Y285 R107 A109 R117 W122 I126 I128 W263 D275 V277 Y281 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.072uM IC50=820nM O75874 31199148 500 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKLS 6o2z A 2.5 BS02 NAP A 1 T75 T77 N96 G289 H309 G310 T311 V312 R314 H315 N328 T73 T75 N94 G285 H305 G306 T307 V308 R310 H311 N324 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 O75874 31199148 501 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKLS 6o2z B 2.5 BS01 LJV B 1 R109 A111 R119 L120 W124 I128 I130 W267 D279 V281 Y285 R107 A109 R117 L118 W122 I126 I128 W263 D275 V277 Y281 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.072uM IC50=820nM O75874 31199148 500 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKLS 6o2z B 2.5 BS02 NAP B 1 T75 T77 R82 N96 S287 H309 G310 T311 V312 R314 H315 N328 D375 T73 T75 R80 N94 S283 H305 G306 T307 V308 R310 H311 N324 D371 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 O75874 31199148 501 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKLS