6nu5 A 1.6 BS01 CYS A 1 R43 N44 N70 H464 G468 I469 F470 R37 N38 N64 H458 G462 I463 F464 R73 R120 K270 T328 R67 R114 K264 T322 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 -logKd/Ki=5.15, Kd=7.04uM P14618 31386812 601 EAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRYAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPFTNTMRVVPVP 6nu5 A 1.6 BS02 OXL A 1 K270 E272 A293 G295 D296 T328 K264 E266 A287 G289 D290 T322 R73 R120 K270 T328 R67 R114 K264 T322 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 31386812 602 EAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRYAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPFTNTMRVVPVP 6nu5 A 1.6 BS03 MG A 1 E272 D296 E266 D290 R73 R120 K270 T328 R67 R114 K264 T322 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 31386812 605 EAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRYAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPFTNTMRVVPVP 6nu5 B 1.6 BS01 CYS B 1 R43 N44 N70 H464 I469 F470 R30 N31 N57 H451 I456 F457 R73 R120 K270 T328 R60 R107 K257 T315 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 31386812 601 QTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRYAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6nu5 B 1.6 BS02 OXL B 1 K270 E272 A293 G295 D296 T328 K257 E259 A280 G282 D283 T315 R73 R120 K270 T328 R60 R107 K257 T315 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 31386812 602 QTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRYAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6nu5 B 1.6 BS03 MG B 1 E272 D296 E259 D283 R73 R120 K270 T328 R60 R107 K257 T315 2.7.10.2,2.7.11.1,2.7.1.40 0000287,0003723,0003729,0003824,0004713,0004743,0005515,0005524,0005576,0005634,0005737,0005739,0005791,0005829,0005929,0006096,0006417,0012501,0016301,0016310,0023026,0030955,0031982,0032869,0034774,0045296,0046872,0061621,0062023,0070062,1903561,1903672,1904813,2000767 P14618 31386812 607 QTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRYAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP