6ncf A 2.871 BS01 FE2 A 1 H367 H372 H550 N554 I673 H369 H374 H552 N556 I675 H367 H372 H550 N554 I673 H369 H374 H552 N556 I675 1.13.11.-,1.13.11.34 0001676,0001937,0002232,0002523,0002540,0004051,0004052,0005506,0005515,0005576,0005615,0005634,0005635,0005641,0005654,0005737,0005829,0006629,0006690,0006691,0006954,0006959,0016020,0016363,0016525,0016702,0016787,0019369,0019370,0019372,0030501,0031965,0034440,0034774,0036336,0036403,0042593,0042759,0045598,0046872,0048471,0050727,0050728,0050796,0051213,0061044,0061045,0106014,1900015,1900407,1901753,1903426,1903573,1903671,1904813,1904999,2001301 P09917 32393899 701 SSHHHHHYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDKGSFERGAVDSYDVTVDEELGEIQLVRIEKRKYGSNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNENLQLPYYYLSPDRIPNSVAI 6ncf B 2.871 BS01 FE2 B 1 H367 H372 H550 N554 I673 H370 H375 H553 N557 I676 H367 H372 H550 N554 I673 H370 H375 H553 N557 I676 1.13.11.-,1.13.11.34 0001676,0001937,0002232,0002523,0002540,0004051,0004052,0005506,0005515,0005576,0005615,0005634,0005635,0005641,0005654,0005737,0005829,0006629,0006690,0006691,0006954,0006959,0016020,0016363,0016525,0016702,0016787,0019369,0019370,0019372,0030501,0031965,0034440,0034774,0036336,0036403,0042593,0042759,0045598,0046872,0048471,0050727,0050728,0050796,0051213,0061044,0061045,0106014,1900015,1900407,1901753,1903426,1903573,1903671,1904813,1904999,2001301 P09917 32393899 701 SSHHHHHSYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDKGSFERGAVDSYDVTVDEELGEIQLVRIEKRKYGSNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNENLQLPYYYLSPDRIPNSVAI 6ncf B 2.871 BS02 AF7 B 1 L66 R68 R101 E108 V109 V110 H130 E134 T137 R138 L69 R71 R104 E111 V112 V113 H133 E137 T140 R141 H367 H372 H550 N554 I673 H370 H375 H553 N557 I676 1.13.11.-,1.13.11.34 0001676,0001937,0002232,0002523,0002540,0004051,0004052,0005506,0005515,0005576,0005615,0005634,0005635,0005641,0005654,0005737,0005829,0006629,0006690,0006691,0006954,0006959,0016020,0016363,0016525,0016702,0016787,0019369,0019370,0019372,0030501,0031965,0034440,0034774,0036336,0036403,0042593,0042759,0045598,0046872,0048471,0050727,0050728,0050796,0051213,0061044,0061045,0106014,1900015,1900407,1901753,1903426,1903573,1903671,1904813,1904999,2001301 IC50=35600nM P09917 32393899 702 SSHHHHHSYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDKGSFERGAVDSYDVTVDEELGEIQLVRIEKRKYGSNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNENLQLPYYYLSPDRIPNSVAI 6ncf C 2.871 BS01 FE2 C 1 H367 H372 H550 N554 I673 H363 H368 H546 N550 I669 H367 H372 H550 N554 I673 H363 H368 H546 N550 I669 1.13.11.-,1.13.11.34 0001676,0001937,0002232,0002523,0002540,0004051,0004052,0005506,0005515,0005576,0005615,0005634,0005635,0005641,0005654,0005737,0005829,0006629,0006690,0006691,0006954,0006959,0016020,0016363,0016525,0016702,0016787,0019369,0019370,0019372,0030501,0031965,0034440,0034774,0036336,0036403,0042593,0042759,0045598,0046872,0048471,0050727,0050728,0050796,0051213,0061044,0061045,0106014,1900015,1900407,1901753,1903426,1903573,1903671,1904813,1904999,2001301 P09917 32393899 701 SYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDKGSFERGAVDSYDVTVDEELGEIQLVRIEKRKYGSNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNENLQLPYYYLSPDRIPNSVAI 6ncf D 2.871 BS01 FE2 D 1 H367 H372 H550 N554 I673 H363 H368 H546 N550 I669 H367 H372 H550 N554 I673 H363 H368 H546 N550 I669 1.13.11.-,1.13.11.34 0001676,0001937,0002232,0002523,0002540,0004051,0004052,0005506,0005515,0005576,0005615,0005634,0005635,0005641,0005654,0005737,0005829,0006629,0006690,0006691,0006954,0006959,0016020,0016363,0016525,0016702,0016787,0019369,0019370,0019372,0030501,0031965,0034440,0034774,0036336,0036403,0042593,0042759,0045598,0046872,0048471,0050727,0050728,0050796,0051213,0061044,0061045,0106014,1900015,1900407,1901753,1903426,1903573,1903671,1904813,1904999,2001301 P09917 32393899 701 SYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDKGSFERGAVDSYDVTVDEELGEIQLVRIEKRKYGSNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNENLQLPYYYLSPDRIPNSVAI