6mdb A 2.34 BS01 JE4 A 1 R111 F113 H114 T219 E249 E250 T253 L254 Q257 P491 K492 Q495 R106 F108 H109 T203 E225 E226 T229 L230 Q233 P453 K454 Q457 D425 C459 R465 T466 Q506 D387 C421 R427 T428 Q468 3.1.3.48 0004725,0006470,0016311 ic50=0.064uM -logKd/Ki=7.17, IC50=0.067uM Q06124 30688459 601 SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQPGDFVLSVRTGDSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPPVSDYINANIIMPKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL 6mdb B 2.34 BS01 JE4 B 1 R111 F113 H114 T219 E249 E250 T253 L254 Q257 P491 K492 Q495 R107 F109 H110 T201 E222 E223 T226 L227 Q230 P447 K448 Q451 D425 C459 R465 T466 Q506 D381 C415 R421 T422 Q462 3.1.3.48 0004725,0006470,0016311 ic50=0.064uM Q06124 30688459 601 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKENGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESPGDFVLSVRTSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHVSDYINANIIMPPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL