6lxy A 2.19 BS01 EXF A 1 I185 M192 V200 A211 V246 Y262 Y264 M265 P266 G268 R273 L318 I23 M30 V38 A49 V84 Y100 Y102 M103 P104 G106 R111 L156 D311 K313 A315 N316 D329 T351 D149 K151 A153 N154 D167 T187 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=3.4nM IC50=920nM Q9NWZ3 32676146 501 TRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 6lxy B 2.19 BS01 EXF B 1 M192 V200 A211 Y262 Y264 M265 P266 G268 R273 L318 M30 V38 A49 Y100 Y102 M103 P104 G106 R111 L156 D311 K313 A315 N316 D329 F339 T351 D149 K151 A153 N154 D167 F177 T189 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=3.4nM IC50=920nM Q9NWZ3 32676146 502 TRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 6lxy D 2.19 BS01 EXF D 1 M192 V200 A211 Y262 Y264 M265 P266 G268 R273 L318 M31 V39 A50 Y101 Y103 M104 P105 G107 R112 L157 D311 K313 A315 N316 D329 T351 D150 K152 A154 N155 D168 T185 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=3.4nM IC50=920nM Q9NWZ3 32676146 502 DTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 6lxy E 2.19 BS01 EXF E 1 M192 V200 A211 Y262 Y264 M265 P266 G268 R273 L318 M29 V37 A48 Y99 Y101 M102 P103 G105 R110 L155 D311 K313 A315 N316 D329 T351 D148 K150 A152 N153 D166 T181 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=3.4nM IC50=920nM Q9NWZ3 32676146 502 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARAVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT