6itj A 1.994 BS01 AXU A 1 F489 V492 A512 K514 V561 Y563 A564 L630 F25 V28 A48 K50 V97 Y99 A100 L154 D623 A625 R627 N628 D641 D147 A149 R151 N152 D165 2.7.10.1 0004672,0004713,0005007,0005524,0006468 ic50=10.8nM -logKd/Ki=7.97, IC50=10.8nM IC50=11nM P11362 31335138 801 LPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE 6itj B 1.994 BS01 AXU B 1 F489 V492 A512 K514 V561 Y563 A564 L630 F31 V34 A54 K56 V103 Y105 A106 L167 D623 A625 R627 N628 D641 D160 A162 R164 N165 D178 2.7.10.1 0004672,0004713,0005007,0005524,0006468 ic50=10.8nM IC50=11nM P11362 31335138 801 GVSEYELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYSYPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT