6hzv A 2.46 BS01 GYW A 1 L828 A853 V884 M902 Y904 L905 G908 C909 D912 R953 L956 L14 A39 V68 M82 Y84 L85 G88 C89 D92 R133 L136 D949 R953 N954 D967 D129 R133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 ic50=59nM -logKd/Ki=8.22, IC50=6nM IC50=59nM P52333 31609613 1101 TIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQGPDQQRDFQREIQILKALHSDFIVKYRGVSYQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVRPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMPALSRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML 6hzv B 2.46 BS01 GYW B 1 L828 A853 M902 Y904 L905 G908 C909 D912 R953 L956 L14 A39 M82 Y84 L85 G88 C89 D92 R133 L136 D949 R953 N954 D967 D129 R133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 ic50=59nM IC50=59nM P52333 31609613 1101 TIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQGPDQQRDFQREIQILKALHSDFIVKYRGVSYQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMRDVPALSRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLW 6hzv C 2.46 BS01 GYW C 1 L828 K830 G831 A853 M902 Y904 L905 G908 C909 D912 L956 L14 K16 G17 A39 M81 Y83 L84 G87 C88 D91 L135 D949 R953 N954 D967 D128 R132 N133 D146 2.7.10.2 0004672,0004713,0005524,0006468 ic50=59nM IC50=59nM P52333 31609613 1101 TIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQGPDQQRDFQREIQILKALHSDFIVKYRGVSYSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMPALSRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML 6hzv D 2.46 BS01 GYW D 1 L828 K830 G831 A853 M902 Y904 L905 C909 D912 L956 L14 K16 G17 A39 M81 Y83 L84 C88 D91 L135 D949 R953 N954 D967 D128 R132 N133 D146 2.7.10.2 0004672,0004713,0005524,0006468 ic50=59nM IC50=59nM P52333 31609613 1101 TIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQGPDQQRDFQREIQILKALHSDFIVKYRGVSYSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAELSRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML