6hvi A 1.96 BS01 GV5 A 1 R45 G46 Y49 I50 S152 C154 V159 N163 E166 V214 V217 I241 V243 R32 G33 Y36 I37 S139 C141 V146 N150 E153 V201 V204 I228 V230 R252 H253 N259 S302 E322 H387 R239 H240 N246 S289 E309 H374 2.7.1.105,3.1.3.46 0003824,0003873,0004331,0005515,0005524,0005654,0005829,0006000,0006003,0006096,0006915,0010001,0016301,0016310,0016787,0046835,0061744 ic50=0.38uM -logKd/Ki=6.42, IC50=0.380uM Q16875 30378281 601 PLELTQSRVQKIWVPVHRNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSE 6hvi A 1.96 BS02 POP A 1 A44 R45 G46 K47 T48 Y49 K168 Y424 A31 R32 G33 K34 T35 Y36 K155 Y411 R252 H253 N259 S302 E322 H387 R239 H240 N246 S289 E309 H374 2.7.1.105,3.1.3.46 0003824,0003873,0004331,0005515,0005524,0005654,0005829,0006000,0006003,0006096,0006915,0010001,0016301,0016310,0016787,0046835,0061744 Q16875 30378281 602 PLELTQSRVQKIWVPVHRNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSE 6hvi A 1.96 BS03 F6P A 1 G265 E322 Y333 R347 K351 Y362 Q388 R392 G252 E309 Y320 R334 K338 Y349 Q375 R379 R252 H253 N259 S302 E322 H387 R239 H240 N246 S289 E309 H374 2.7.1.105,3.1.3.46 0003824,0003873,0004331,0005515,0005524,0005654,0005829,0006000,0006003,0006096,0006915,0010001,0016301,0016310,0016787,0046835,0061744 Q16875 30378281 603 PLELTQSRVQKIWVPVHRNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSE