6hgz A 1.86 BS01 MG A 1 T62 D63 D64 D305 T54 D55 D56 D279 3.2.1.143,3.2.2.-,3.5.1.- 0000287,0004649,0005634,0005694,0005737,0005739,0005759,0006281,0016787,0046872,0060546,0140290 H3BCW1 30472116 401 MVSLAQVRGALCGALLGDCMGAEFEGSDAVELPDVLEFVRLLEKEKKAGTLFYTDDTAMTRAVIQSLIAKPDFDEVDMAKRFAEEYKKEPTRGYGAGVVQVFKKLLSPKYSDVFQPAREQFDGKGSYGNGGAMRVASIALAYPNIQDVIKFARRSAQLTHASPLGYNGAILQALAVHFALQGELKRDTFLEQLIGEMERIEGLPFCSRLKKIKEFLASSNVPKADIVDELGHGIAALESVPTAIYSFLHCMESDPDIPDLYNNLQRTIIYSISLGGDTDTIATMAGAIAGAYYGMDQVTPSWKRSCEAIVETEESAVKLYELYCKQL 6hgz A 1.86 BS02 MG A 2 E33 D303 D305 T306 E25 D277 D279 T280 3.2.1.143,3.2.2.-,3.5.1.- 0000287,0004649,0005634,0005694,0005737,0005739,0005759,0006281,0016787,0046872,0060546,0140290 H3BCW1 30472116 402 MVSLAQVRGALCGALLGDCMGAEFEGSDAVELPDVLEFVRLLEKEKKAGTLFYTDDTAMTRAVIQSLIAKPDFDEVDMAKRFAEEYKKEPTRGYGAGVVQVFKKLLSPKYSDVFQPAREQFDGKGSYGNGGAMRVASIALAYPNIQDVIKFARRSAQLTHASPLGYNGAILQALAVHFALQGELKRDTFLEQLIGEMERIEGLPFCSRLKKIKEFLASSNVPKADIVDELGHGIAALESVPTAIYSFLHCMESDPDIPDLYNNLQRTIIYSISLGGDTDTIATMAGAIAGAYYGMDQVTPSWKRSCEAIVETEESAVKLYELYCKQL 6hgz A 1.86 BS03 AR6 A 1 D63 G103 G105 F129 S134 Y135 G136 N137 G138 H168 I260 D303 T306 D55 G95 G97 F121 S126 Y127 G128 N129 G130 H160 I234 D277 T280 3.2.1.143,3.2.2.-,3.5.1.- 0000287,0004649,0005634,0005694,0005737,0005739,0005759,0006281,0016787,0046872,0060546,0140290 -logKd/Ki=5.97, Ki=1.08uM H3BCW1 30472116 403 MVSLAQVRGALCGALLGDCMGAEFEGSDAVELPDVLEFVRLLEKEKKAGTLFYTDDTAMTRAVIQSLIAKPDFDEVDMAKRFAEEYKKEPTRGYGAGVVQVFKKLLSPKYSDVFQPAREQFDGKGSYGNGGAMRVASIALAYPNIQDVIKFARRSAQLTHASPLGYNGAILQALAVHFALQGELKRDTFLEQLIGEMERIEGLPFCSRLKKIKEFLASSNVPKADIVDELGHGIAALESVPTAIYSFLHCMESDPDIPDLYNNLQRTIIYSISLGGDTDTIATMAGAIAGAYYGMDQVTPSWKRSCEAIVETEESAVKLYELYCKQL 6hgz B 1.86 BS01 MG B 1 T62 D63 D64 D305 T54 D55 D56 D279 3.2.1.143,3.2.2.-,3.5.1.- 0000287,0004649,0005634,0005694,0005737,0005739,0005759,0006281,0016787,0046872,0060546,0140290 H3BCW1 30472116 401 MVSLAQVRGALCGALLGDCMGAEFEGSDAVELPDVLEFVRLLEKEKKAGTLFYTDDTAMTRAVIQSLIAKPDFDEVDMAKRFAEEYKKEPTRGYGAGVVQVFKKLLSPKYSDVFQPAREQFDGKGSYGNGGAMRVASIALAYPNIQDVIKFARRSAQLTHASPLGYNGAILQALAVHFALQGELKRDTFLEQLIGEMERIEGLPFCSRLKKIKEFLASSNVPKADIVDELGHGIAALESVPTAIYSFLHCMESDPDIPDLYNNLQRTIIYSISLGGDTDTIATMAGAIAGAYYGMDQVTPSWKRSCEAIVETEESAVKLYELYCKQL 6hgz B 1.86 BS02 MG B 2 E33 D303 D305 T306 E25 D277 D279 T280 3.2.1.143,3.2.2.-,3.5.1.- 0000287,0004649,0005634,0005694,0005737,0005739,0005759,0006281,0016787,0046872,0060546,0140290 H3BCW1 30472116 402 MVSLAQVRGALCGALLGDCMGAEFEGSDAVELPDVLEFVRLLEKEKKAGTLFYTDDTAMTRAVIQSLIAKPDFDEVDMAKRFAEEYKKEPTRGYGAGVVQVFKKLLSPKYSDVFQPAREQFDGKGSYGNGGAMRVASIALAYPNIQDVIKFARRSAQLTHASPLGYNGAILQALAVHFALQGELKRDTFLEQLIGEMERIEGLPFCSRLKKIKEFLASSNVPKADIVDELGHGIAALESVPTAIYSFLHCMESDPDIPDLYNNLQRTIIYSISLGGDTDTIATMAGAIAGAYYGMDQVTPSWKRSCEAIVETEESAVKLYELYCKQL 6hgz B 1.86 BS03 AR6 B 1 E33 D63 G103 G105 V106 F129 S134 Y135 G136 N137 G138 H168 I260 D303 T306 E25 D55 G95 G97 V98 F121 S126 Y127 G128 N129 G130 H160 I234 D277 T280 3.2.1.143,3.2.2.-,3.5.1.- 0000287,0004649,0005634,0005694,0005737,0005739,0005759,0006281,0016787,0046872,0060546,0140290 H3BCW1 30472116 403 MVSLAQVRGALCGALLGDCMGAEFEGSDAVELPDVLEFVRLLEKEKKAGTLFYTDDTAMTRAVIQSLIAKPDFDEVDMAKRFAEEYKKEPTRGYGAGVVQVFKKLLSPKYSDVFQPAREQFDGKGSYGNGGAMRVASIALAYPNIQDVIKFARRSAQLTHASPLGYNGAILQALAVHFALQGELKRDTFLEQLIGEMERIEGLPFCSRLKKIKEFLASSNVPKADIVDELGHGIAALESVPTAIYSFLHCMESDPDIPDLYNNLQRTIIYSISLGGDTDTIATMAGAIAGAYYGMDQVTPSWKRSCEAIVETEESAVKLYELYCKQL