6g07 A 1.66 BS01 peptide P 0 K336 Q346 Q349 I350 P500 L501 E504 K73 Q83 Q86 I87 P237 L238 E241 ? 0003677,0004879,0005634,0006355 P51449 29990434 499 ~ 507 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFST 6g07 A 1.66 BS02 peptide R 0 I492 Q495 I229 Q232 ? 0003677,0004879,0005634,0006355 P51449 29990434 498 ~ 507 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFST 6g07 A 1.66 BS03 EEZ A 1 Q286 L287 C320 R364 M365 R367 A368 F377 F378 F388 I400 Q23 L24 C57 R101 M102 R104 A105 F114 F115 F125 I137 ? 0003677,0004879,0005634,0006355 Kd=35.5nM -logKd/Ki=4.57, IC50=27uM IC50=255nM, Kd=36nM P51449 29990434 601 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFST 6g07 B 1.66 BS01 peptide Q 0 K336 Q346 Q349 I350 P500 L501 E504 K73 Q83 Q86 I87 P237 L238 E241 ? 0003677,0004879,0005634,0006355 P51449 29990434 498 ~ 508 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFST 6g07 B 1.66 BS02 EEZ B 1 Q286 L287 C320 L324 M365 R367 A368 F377 F378 F388 I400 Q23 L24 C57 L61 M102 R104 A105 F114 F115 F125 I137 ? 0003677,0004879,0005634,0006355 Kd=35.5nM IC50=255nM, Kd=36nM P51449 29990434 601 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFST 6g07 C 1.66 BS01 peptide P 0 I492 Q495 I229 Q232 ? 0003677,0004879,0005634,0006355 P51449 29990434 499 ~ 507 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTE 6g07 C 1.66 BS02 peptide R 0 K336 Q346 Q349 I350 P500 L501 E504 K73 Q83 Q86 I87 P237 L238 E241 ? 0003677,0004879,0005634,0006355 P51449 29990434 498 ~ 507 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTE 6g07 C 1.66 BS03 EEZ C 1 Q286 L287 C320 R364 M365 R367 A368 F377 F378 F388 I400 Q23 L24 C57 R101 M102 R104 A105 F114 F115 F125 I137 ? 0003677,0004879,0005634,0006355 Kd=35.5nM IC50=255nM, Kd=36nM P51449 29990434 601 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTE 6g07 D 1.66 BS01 peptide S 0 K336 Q346 Q349 I350 P500 L501 E504 K73 Q83 Q86 I87 P237 L238 E241 ? 0003677,0004879,0005634,0006355 P51449 29990434 498 ~ 507 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFST 6g07 D 1.66 BS02 EEZ D 1 Q286 L287 C320 M365 R367 A368 F377 F378 F388 I400 Q23 L24 C57 M102 R104 A105 F114 F115 F125 I137 ? 0003677,0004879,0005634,0006355 Kd=35.5nM IC50=255nM, Kd=36nM P51449 29990434 601 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFST