6ft9 A 1.87 BS01 E6W A 1 L167 G168 V175 A189 F241 E242 L244 E292 L295 L21 G22 V29 A43 F95 E96 L98 E146 L149 D288 K290 N293 D325 T342 D142 K144 N147 D179 T196 2.7.12.1 0004672,0005524,0006468 -logKd/Ki=6.96, IC50=0.11uM P49759 29723265 501 MHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKK 6ft9 B 1.87 BS01 E6W B 1 L167 F172 V175 A189 F241 E242 L244 E292 L295 L22 F27 V30 A44 F96 E97 L99 E147 L150 D288 K290 N293 D325 T342 D143 K145 N148 D180 T197 2.7.12.1 0004672,0005524,0006468 P49759 29723265 501 SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKK 6ft9 C 1.87 BS01 E6W C 1 L167 G168 E169 V175 A189 F241 E242 L244 E292 L295 L22 G23 E24 V30 A44 F96 E97 L99 E147 L150 D288 K290 N293 D325 T342 D143 K145 N148 D180 T197 2.7.12.1 0004672,0005524,0006468 P49759 29723265 501 SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKK