6e6j A 2.44 BS01 HWV A 1 W370 P371 V376 D377 L381 N429 V435 W25 P26 V31 D32 L36 N84 V90 ? -logKd/Ki=8.10, IC50=8nM Ki=4.6nM P25440 31969702 501 HMEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 6e6j B 2.44 BS01 HWV B 1 W370 P371 V376 D377 L381 N429 H433 V435 W25 P26 V31 D32 L36 N84 H88 V90 ? Ki=4.6nM P25440 31969702 501 HMEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 6e6j C 2.44 BS01 HWV C 1 W370 P371 F372 V376 D377 L381 N429 H433 V435 W25 P26 F27 V31 D32 L36 N84 H88 V90 ? Ki=4.6nM P25440 31969702 501 HMEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 6e6j D 2.44 BS01 HWV D 1 W370 P371 V376 D377 L381 N429 V435 W25 P26 V31 D32 L36 N84 V90 ? Ki=4.6nM P25440 31969702 501 HMEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 6e6j E 2.44 BS01 HWV E 1 W370 V376 D377 L381 Y428 N429 H433 V435 W25 V31 D32 L36 Y83 N84 H88 V90 ? Ki=4.6nM P25440 31969702 501 HMEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 6e6j F 2.44 BS01 HWV F 1 W370 P371 V376 D377 L381 L383 N429 V435 W25 P26 V31 D32 L36 L38 N84 V90 ? Ki=4.6nM P25440 31969702 501 HMEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP