6e3g A 2.1 BS01 peptide C 0 K336 Q346 Q349 L501 E504 K74 Q84 Q87 L239 E242 ? 0003677,0004879,0005634,0006355 P51449 30652849 1 ~ 8 PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 6e3g A 2.1 BS02 HOJ A 1 W317 C320 L324 M358 V361 M365 A368 F377 F378 E379 F388 I400 H479 W55 C58 L62 M96 V99 M103 A106 F115 F116 E117 F126 I138 H217 ? 0003677,0004879,0005634,0006355 ic50=44nM -logKd/Ki=7.36, IC50=44nM IC50=44nM, EC50=53nM P51449 30652849 602 PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 6e3g B 2.1 BS01 peptide D 0 K336 Q346 Q349 I350 L501 E504 K74 Q84 Q87 I88 L239 E242 ? 0003677,0004879,0005634,0006355 P51449 30652849 1 ~ 8 PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 6e3g B 2.1 BS02 HOJ B 1 W317 C320 L324 M358 V361 F377 F378 E379 F388 I400 H479 W55 C58 L62 M96 V99 F115 F116 E117 F126 I138 H217 ? 0003677,0004879,0005634,0006355 ic50=44nM IC50=44nM, EC50=53nM P51449 30652849 602 PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS