6dkg A 2.53 BS01 22L A 1 K513 W514 E515 K14 W15 E16 D650 R654 N655 D668 D139 R143 N144 D157 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 P04629 29944371 801 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGYSTDYYRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLG 6dkg A 2.53 BS02 GO7 A 1 L516 V524 A542 L564 F589 Y591 M592 F646 H648 L657 I666 G667 D668 F669 L17 V25 A43 L65 F90 Y92 M93 F135 H137 L146 I155 G156 D157 F158 D650 R654 N655 D668 D139 R143 N144 D157 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 -logKd/Ki=8.59, Kd=2.6nM IC50=7700nM, Kd=1.1nM P04629 29944371 802 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGYSTDYYRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLG