6bt0 A 2.6 BS01 GDP A 1 S16 G18 K19 S20 S21 K120 D122 L123 S149 A150 S14 G16 K17 S18 S19 K118 D120 L121 S147 A148 3.6.5.- 0000139,0000287,0003924,0005515,0005525,0005681,0005737,0005764,0005765,0005783,0005789,0005794,0005829,0005886,0007165,0007264,0012505,0014069,0016020,0016241,0016787,0019003,0019901,0030295,0031669,0032006,0032008,0043539,0045202,0046872,0048709,0048714,0051726,0070062,0120163,1904263,2000074 Q15382 29416044 202 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKLE 6bt0 B 2.6 BS01 GDP B 1 S16 G18 K19 S20 S21 F31 N119 K120 D122 L123 S149 A150 S14 G16 K17 S18 S19 F29 N117 K118 D120 L121 S147 A148 3.6.5.- 0000139,0000287,0003924,0005515,0005525,0005681,0005737,0005764,0005765,0005783,0005789,0005794,0005829,0005886,0007165,0007264,0012505,0014069,0016020,0016241,0016787,0019003,0019901,0030295,0031669,0032006,0032008,0043539,0045202,0046872,0048709,0048714,0051726,0070062,0120163,1904263,2000074 Q15382 29416044 202 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKL 6bt0 B 2.6 BS02 E7V B 1 E40 A62 G63 F70 Y74 E38 A60 G61 F68 Y72 3.6.5.- 0000139,0000287,0003924,0005515,0005525,0005681,0005737,0005764,0005765,0005783,0005789,0005794,0005829,0005886,0007165,0007264,0012505,0014069,0016020,0016241,0016787,0019003,0019901,0030295,0031669,0032006,0032008,0043539,0045202,0046872,0048709,0048714,0051726,0070062,0120163,1904263,2000074 -logKd/Ki=5.68, IC50=2.1uM Q15382 29416044 203 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKL 6bt0 C 2.6 BS01 GDP C 1 S16 V17 G18 K19 S20 S21 F31 D33 N119 K120 D122 L123 S149 A150 S14 V15 G16 K17 S18 S19 F29 D31 N117 K118 D120 L121 S147 A148 3.6.5.- 0000139,0000287,0003924,0005515,0005525,0005681,0005737,0005764,0005765,0005783,0005789,0005794,0005829,0005886,0007165,0007264,0012505,0014069,0016020,0016241,0016787,0019003,0019901,0030295,0031669,0032006,0032008,0043539,0045202,0046872,0048709,0048714,0051726,0070062,0120163,1904263,2000074 Q15382 29416044 202 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKL 6bt0 D 2.6 BS01 GDP D 1 S16 G18 K19 S20 S21 D33 N119 K120 D122 L123 S149 A150 S14 G16 K17 S18 S19 D31 N117 K118 D120 L121 S147 A148 3.6.5.- 0000139,0000287,0003924,0005515,0005525,0005681,0005737,0005764,0005765,0005783,0005789,0005794,0005829,0005886,0007165,0007264,0012505,0014069,0016020,0016241,0016787,0019003,0019901,0030295,0031669,0032006,0032008,0043539,0045202,0046872,0048709,0048714,0051726,0070062,0120163,1904263,2000074 Q15382 29416044 202 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKL