6b16 A 2.285 BS01 C7Y A 1 A297 E345 Y346 L347 D393 L396 T406 A47 E88 Y89 L90 D136 L139 T149 N389 K391 D393 N394 D407 P416 T427 N132 K134 D136 N137 D150 P159 T170 2.7.11.1 0004672,0005524,0006468 Ki=32nM -logKd/Ki=7.49, Ki=32nM Ki=32nM Q13153 27346791 601 EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQQPKKELIINEILVMRENKNPNIVNYLDSYLDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRNIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATK 6b16 B 2.285 BS01 C7Y B 1 A297 Y346 L347 G350 D393 N394 L396 T406 A43 Y92 L93 G96 D139 N140 L142 T152 N389 K391 D393 N394 D407 T427 N135 K137 D139 N140 D153 T166 2.7.11.1 0004672,0005524,0006468 Ki=32nM Ki=32nM Q13153 27346791 601 EKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRNIKSDNILLGMDGSVKLTDFGEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATK