6b0z A 2.334 BS01 NDP A 1 T75 T77 N96 H309 G310 T311 V312 T313 R314 H315 T327 N328 T73 T75 N94 H296 G297 T298 V299 T300 R301 H302 T314 N315 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 O75874 29057061 501 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 6b0z A 2.334 BS02 C81 A 1 R109 A111 R119 L120 W124 I128 I130 M259 S278 Y285 M291 R107 A109 R117 L118 W122 I126 I128 M251 S265 Y272 M278 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.018uM IC50=50nM O75874 29057061 502 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 6b0z A 2.334 BS03 C81 A 2 H132 C269 Q277 S278 H130 C261 Q264 S265 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.018uM IC50=50nM O75874 29057061 504 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 6b0z B 2.334 BS01 NDP B 1 A74 T75 T77 N96 Q283 L288 H309 G310 T311 V312 T313 R314 H315 T327 N328 A72 T73 T75 N94 Q279 L284 H305 G306 T307 V308 T309 R310 H311 T323 N324 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 O75874 29057061 501 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 6b0z B 2.334 BS02 C81 B 1 R109 A111 I113 R119 L120 W124 I128 I130 W267 S278 V281 R107 A109 I111 R117 L118 W122 I126 I128 W263 S274 V277 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.018uM IC50=50nM O75874 29057061 502 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 6b0z B 2.334 BS03 C81 D 2 Q277 V281 Q273 V277 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.018uM IC50=50nM O75874 29057061 504 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 6b0z C 2.334 BS01 C81 A 2 Q277 V281 Q273 V277 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.018uM IC50=50nM O75874 29057061 504 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 6b0z C 2.334 BS02 NDP C 1 T75 T77 R82 N96 H309 G310 T311 V312 T313 R314 H315 N328 T73 T75 R80 N94 H305 G306 T307 V308 T309 R310 H311 N324 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 O75874 29057061 501 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 6b0z C 2.334 BS03 C81 C 1 R109 A111 R119 L120 I128 I130 S278 M291 R107 A109 R117 L118 I126 I128 S274 M287 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.018uM IC50=50nM O75874 29057061 502 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHADQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 6b0z D 2.334 BS01 NDP D 1 T75 T77 N96 L288 H309 G310 T311 V312 R314 H315 T327 N328 T73 T75 N94 L276 H297 G298 T299 V300 R302 H303 T315 N316 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 O75874 29057061 501 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHARATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 6b0z D 2.334 BS02 C81 D 1 R109 A111 R119 L120 W124 I128 I130 M259 A282 Y285 M291 R107 A109 R117 L118 W122 I126 I128 M252 A270 Y273 M279 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.018uM IC50=50nM O75874 29057061 502 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHARATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 6b0z D 2.334 BS03 C81 D 2 H132 V255 Q277 S278 V281 H130 V248 Q265 S266 V269 1.1.1.42 0000287,0004450,0005515,0005576,0005737,0005739,0005777,0005782,0005829,0006097,0006099,0006102,0006103,0006739,0006749,0006979,0008585,0014070,0016491,0016616,0034774,0042802,0042803,0045296,0046872,0048545,0050661,0051287,0060696,0070062,0071071,1904724,1904813 ic50=0.018uM IC50=50nM O75874 29057061 504 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHARATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ