5zh4 A 2.6 BS01 LYS A 1 G284 E308 E346 N503 Y505 E507 G552 G203 E227 E265 N415 Y417 E419 G443 R330 E332 T337 H338 E500 N503 R559 R249 E251 T256 H257 E412 N415 R450 6.1.1.6 0000049,0000166,0003676,0004812,0004824,0005524,0005737,0005829,0006418,0006430,0016874 W7JP72 29779382 601 EVDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKEAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRP 5zh4 A 2.6 BS02 9CC A 1 E332 H338 N339 F342 V501 L502 R559 E251 H257 N258 F261 V413 L414 R450 R330 E332 T337 H338 E500 N503 R559 R249 E251 T256 H257 E412 N415 R450 6.1.1.6 0000049,0000166,0003676,0004812,0004824,0005524,0005737,0005829,0006418,0006430,0016874 -logKd/Ki=5.14, IC50=7.25uM W7JP72 29779382 602 EVDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKEAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRP 5zh4 B 2.6 BS01 LYS B 1 G284 E308 E346 Y348 N503 Y505 E507 G552 G194 E218 E256 Y258 N413 Y415 E417 G447 R330 E332 T337 H338 E500 N503 R559 R240 E242 T247 H248 E410 N413 R454 6.1.1.6 0000049,0000166,0003676,0004812,0004824,0005524,0005737,0005829,0006418,0006430,0016874 W7JP72 29779382 601 EVDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSLSIFPKETILLSACLHMLPEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFQLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRP 5zh4 B 2.6 BS02 9CC B 1 H338 N339 F342 E500 V501 L502 G554 R559 H248 N249 F252 E410 V411 L412 G449 R454 R330 E332 T337 H338 E500 N503 R559 R240 E242 T247 H248 E410 N413 R454 6.1.1.6 0000049,0000166,0003676,0004812,0004824,0005524,0005737,0005829,0006418,0006430,0016874 W7JP72 29779382 602 EVDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSLSIFPKETILLSACLHMLPEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFQLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRP