5yjp A 1.8 BS01 ZN A 1 H25 E77 H10 E64 H57 D102 K192 G193 D194 S195 H45 D89 K173 G174 D175 S176 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 P23946 29191554 303 IIGGTESKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 5yjp A 1.8 BS02 8W6 A 1 F41 C42 H57 R143 A190 F191 K192 S195 S214 G216 R217 F29 C30 H45 R124 A171 F172 K173 S176 S191 G193 R194 H57 D102 K192 G193 D194 S195 H45 D89 K173 G174 D175 S176 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 ic50=0.24uM -logKd/Ki=6.62, IC50=0.24uM IC50=240nM P23946 29191554 304 IIGGTESKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN