5yft A 2.21 BS01 RI2 A 1 R22 G23 A24 G25 R65 S137 K138 A139 N204 N214 K215 K240 F281 R20 G21 A22 G23 R63 S135 K136 A137 N202 N212 K213 K238 F279 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 Kd=10uM -logKd/Ki=5.00, Kd=10uM O57947 29382938 401 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yft B 2.21 BS01 RI2 B 1 M19 R22 G23 A24 R65 S137 K138 A139 N204 N214 K215 K240 F281 M17 R20 G21 A22 R63 S135 K136 A137 N202 N212 K213 K238 F279 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 Kd=10uM O57947 29382938 401 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yft C 2.21 BS01 RI2 C 1 M19 R22 G23 A24 R65 S137 K138 A139 A203 N204 N214 K215 K240 F281 M17 R20 G21 A22 R63 S135 K136 A137 A201 N202 N212 K213 K238 F279 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 Kd=10uM O57947 29382938 401 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED