5ybi A 2.268 BS01 ANP A 1 G162 G164 K165 T166 F167 F339 Y412 G82 G84 K85 T86 F87 F258 Y319 K165 E188 R189 R350 K85 E108 R109 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 -logKd/Ki=3.49, Kd=322.48uM P0A1C1 30013545 505 SHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFDPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTISQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi A 2.268 BS02 MG A 1 G290 K291 G210 K211 K165 E188 R189 R350 K85 E108 R109 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 510 SHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFDPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTISQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi A 2.268 BS03 MG A 2 M171 P340 M91 P259 K165 E188 R189 R350 K85 E108 R109 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 512 SHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFDPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTISQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi A 2.268 BS04 MG A 3 T417 Y418 T324 Y325 K165 E188 R189 R350 K85 E108 R109 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 513 SHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFDPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTISQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi A 2.268 BS05 MG A 4 Q86 G100 Q6 G20 K165 E188 R189 R350 K85 E108 R109 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 514 SHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFDPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTISQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi A 2.268 BS06 MG A 5 L146 R368 L66 R287 K165 E188 R189 R350 K85 E108 R109 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 515 SHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFDPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTISQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi A 2.268 BS07 MG A 6 R189 R191 R109 R111 K165 E188 R189 R350 K85 E108 R109 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 519 SHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFDPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTISQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi A 2.268 BS08 MG A 7 V87 G88 I233 F236 F237 V7 G8 I153 F156 F157 K165 E188 R189 R350 K85 E108 R109 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 521 SHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFDPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTISQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS01 MG B 1 I186 S250 R253 I105 S169 R172 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 504 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS02 MG B 2 G177 A178 Y181 K205 G96 A97 Y100 K124 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 505 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS03 MG B 3 I342 S344 I261 S263 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 506 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS04 MG B 4 M169 D249 M88 D168 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 507 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS05 MG B 5 H4 M5 D120 H1 M2 D39 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 508 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS06 MG B 6 R117 P118 N121 R36 P37 N40 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 509 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS07 MG B 7 E195 T196 E114 T115 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 512 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS08 MG B 8 T85 L99 G100 T4 L18 G19 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 516 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS09 MG B 9 Q86 G100 Q5 G19 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 521 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS10 MG B 10 E373 K400 E292 K315 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 522 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR 5ybi B 2.268 BS11 MG B 11 F279 E318 F198 E237 K165 E188 R189 R350 K84 E107 R108 R269 7.4.2.8 0005524,0005737,0009058,0016887,0030254,0030257 P0A1C1 30013545 524 HMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR