5xvg A 2.1 BS01 8FX A 1 I327 G328 A348 M395 E396 F397 L398 E399 G401 D444 L447 D458 I29 G30 A50 M97 E98 F99 L100 E101 G103 D146 L149 D160 D440 K442 D444 S445 D458 K467 T478 D142 K144 D146 S147 D160 K169 T180 2.7.11.1 0004672,0005524,0006468 Ki=0.009uM -logKd/Ki=8.05, Ki=0.009uM IC50=11nM, Ki=9nM O96013 29190083 601 SSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR