5x2a A 1.85 BS01 7XO A 1 V726 A743 K745 M790 M793 P794 G796 D855 V27 A44 K46 M91 M94 P95 G97 D156 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 IC50=5nM P00533 29568384 1107 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMVV 5x2a A 1.85 BS02 ANP A 1 S720 G721 V726 K745 D837 R841 N842 D855 S21 G22 V27 K46 D138 R142 N143 D156 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 P00533 29568384 1108 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMVV 5x2a B 1.85 BS01 7XO B 1 M793 P794 G796 M94 P95 G97 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 IC50=5nM P00533 29568384 1105 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQG 5x2a B 1.85 BS02 ANP B 1 G719 G721 V726 A743 K745 M793 R841 N842 L844 G20 G22 V27 A44 K46 M94 R142 N143 L145 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 P00533 29568384 1106 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQG 5x2a C 1.85 BS01 7XO C 1 V726 A743 K745 M790 M793 G796 L844 D855 V27 A44 K46 M91 M94 G97 L145 D156 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 IC50=5nM P00533 29568384 1104 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADE 5x2a D 1.85 BS01 ANP D 1 G721 A722 V726 A743 K745 M790 M793 C797 D837 R841 N842 L844 G21 A22 V26 A43 K45 M87 M90 C94 D134 R138 N139 L141 D837 A839 R841 N842 D855 D134 A136 R138 N139 D152 2.7.10.1 0004672,0004713,0005524,0006468 P00533 29568384 1102 QALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEVVDAD 5x2a D 1.85 BS02 MG D 1 N842 D855 N139 D152 D837 A839 R841 N842 D855 D134 A136 R138 N139 D152 2.7.10.1 0004672,0004713,0005524,0006468 P00533 29568384 1103 QALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEVVDAD