5wmt A 2.748 BS01 9QY A 1 N107 D149 M154 N162 F195 T245 I247 N34 D76 M81 N89 F109 T159 I161 ? 0005524,0006457,0016887,0051082,0140662 -logKd/Ki=5.86, Kd=1.38uM Ki=440nM, IC50=1100nM, Kd=1380nM P41148 29528635 405 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTKTVWDWELMN 5wmt B 2.748 BS01 MG B 1 W282 W331 W200 W207 ? 0005524,0006457,0016887,0051082,0140662 P41148 29528635 404 KSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTTVWDWELMN 5wmt B 2.748 BS02 9QY B 1 N107 D149 M154 N162 F195 W223 I247 N36 D78 M83 N91 F113 W141 I165 ? 0005524,0006457,0016887,0051082,0140662 Ki=440nM, IC50=1100nM, Kd=1380nM P41148 29528635 405 KSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTTVWDWELMN 5wmt C 2.748 BS01 MG C 1 W282 W331 W199 W206 ? 0005524,0006457,0016887,0051082,0140662 P41148 29528635 405 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTTVWDWELMN 5wmt C 2.748 BS02 9QY C 1 D149 M154 N162 L163 F195 W223 I247 D76 M81 N89 L90 F112 W140 I164 ? 0005524,0006457,0016887,0051082,0140662 Ki=440nM, IC50=1100nM, Kd=1380nM P41148 29528635 406 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTTVWDWELMN 5wmt D 2.748 BS01 9QY D 1 N107 D149 M154 N162 L163 F195 T245 I247 N34 D76 M81 N89 L90 F109 T159 I161 ? 0005524,0006457,0016887,0051082,0140662 Ki=440nM, IC50=1100nM, Kd=1380nM P41148 29528635 405 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTKTVWDWELMN