5w85 A 2.25 BS01 9YS A 1 G193 V200 A211 K213 V246 Y262 V263 Y264 M265 P266 G268 D272 L318 G30 V36 A47 K49 V74 Y90 V91 Y92 M93 P94 G96 D100 L146 D311 K313 A315 N316 D329 T351 D139 K141 A143 N144 D157 T174 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=10nM -logKd/Ki=8.00, IC50=10nM IC50=10.0nM Q9NWZ3 28947151 4000 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGFGVVYKGYVNNTTVAVKKLEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 5w85 B 2.25 BS01 9YS B 1 M192 G193 V200 A211 V246 Y262 V263 Y264 M265 G268 D272 L318 M29 G30 V35 A46 V73 Y89 V90 Y91 M92 G95 D99 L145 D311 K313 A315 N316 D329 T351 D138 K140 A142 N143 D156 T174 2.7.11.1 0000287,0004672,0004674,0005524,0006468,0007165 ic50=10nM IC50=10.0nM Q9NWZ3 28947151 4000 RFHSFSFYELKNVTNNFDERPISVGGNKMGEFGVVYKGYVNNTTVAVKKLEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA