5vnd A 2.2 BS01 9ES A 1 V492 L494 A512 K514 E531 I545 V561 C563 A564 G567 E571 L630 A640 D641 V30 L32 A50 K52 E69 I83 V99 C101 A102 G105 E109 L168 A178 D179 D623 A625 R627 N628 D641 D161 A163 R165 N166 D179 2.7.10.1 0004672,0004713,0005007,0005524,0006468 -logKd/Ki=6.49, IC50=320nM P11362 29247039 801 YELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVECASKGNLREYLQARRPPGLEYSYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE 5vnd B 2.2 BS01 9ES B 1 L494 K514 E531 I545 V561 C563 A564 G567 E571 L630 A640 D641 F642 L35 K55 E72 I86 V102 C104 A105 G108 E112 L160 A170 D171 F172 D623 A625 R627 N628 D641 D153 A155 R157 N158 D171 2.7.10.1 0004672,0004713,0005007,0005524,0006468 P11362 29247039 801 VSEYELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVECASKGNLREYLQARRPPGEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE