5vlr A 2.8 BS01 9EM A 1 T750 M752 W760 I777 K779 Y813 I825 E826 V828 T833 M900 I910 D911 T665 M667 W675 I688 K690 Y724 I736 E737 V739 T744 M802 I812 D813 2.7.1.137,2.7.1.153 0001779,0001819,0001938,0002250,0002551,0002679,0005515,0005524,0005737,0005829,0005886,0005942,0005943,0006468,0006629,0006935,0006954,0006955,0007165,0010595,0010628,0010818,0016301,0016303,0016310,0030101,0030154,0030183,0030217,0030335,0030593,0033031,0035005,0035747,0035754,0036092,0038084,0042110,0042113,0043303,0043491,0045087,0045766,0046854,0046934,0048015,0050852,0050853,0060374,0072672,1905278 -logKd/Ki=8.52, IC50=3nM IC50=3.00nM O00329 28541707 4001 NQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFHMLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLLIGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATEDYTLQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDLWSLEQPFRIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKILELGRHTEEEQLQLREILEGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEASVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKT