5vlo A 2.05 BS01 9EJ A 1 L20 G21 V28 A41 V74 F90 L92 V93 L143 D157 L13 G14 V18 A31 V64 F80 L82 V83 L133 D147 D136 K138 E140 N141 D157 T177 D126 K128 E130 N131 D147 T167 2.7.11.17 0004672,0005524,0006468 EC50=24.3nM, IC50=0.200nM Q13557 401 TRFTDEYQLFEELGFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 5vlo B 2.05 BS01 9EJ B 1 L20 G21 K22 V28 A41 F90 L92 V93 G96 E97 E140 L143 D157 L14 G15 K16 V22 A35 F84 L86 V87 G90 E91 E134 L137 D151 D136 K138 E140 N141 D157 T177 D130 K132 E134 N135 D151 T171 2.7.11.17 0004672,0005524,0006468 EC50=24.3nM, IC50=0.200nM Q13557 401 CTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRK