5v9f A 2.05 BS01 MN A 1 K244 H264 K290 D311 K242 H262 K288 D309 R87 Y235 K244 H264 S286 C288 D311 R405 R85 Y233 K242 H262 S284 C286 D309 R403 2.7.11.-,4.1.1.32 0000287,0004550,0004611,0004613,0005525,0005737,0005783,0005829,0006006,0006094,0006107,0006629,0009617,0014823,0016301,0016310,0016831,0017076,0018105,0019003,0019543,0030145,0031406,0031667,0032496,0032868,0032869,0033993,0042593,0042594,0043382,0043648,0045944,0046166,0046327,0046872,0046889,0046890,0051365,0070365,0070741,0071300,0071320,0071332,0071333,0071347,0071356,0071377,0071456,0071474,0071475,0071476,0071477,0071549,0072350,0097403,0106264,1904628,1904640 P07379 28345895 702 PQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEAVIMRDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM 5v9f A 2.05 BS02 GTP A 1 S286 A287 G289 K290 T291 N292 V335 R405 R436 W516 F517 G529 F530 S284 A285 G287 K288 T289 N290 V333 R403 R434 W505 F506 G518 F519 R87 Y235 K244 H264 S286 C288 D311 R405 R85 Y233 K242 H262 S284 C286 D309 R403 2.7.11.-,4.1.1.32 0000287,0004550,0004611,0004613,0005525,0005737,0005783,0005829,0006006,0006094,0006107,0006629,0009617,0014823,0016301,0016310,0016831,0017076,0018105,0019003,0019543,0030145,0031406,0031667,0032496,0032868,0032869,0033993,0042593,0042594,0043382,0043648,0045944,0046166,0046327,0046872,0046889,0046890,0051365,0070365,0070741,0071300,0071320,0071332,0071333,0071347,0071356,0071377,0071456,0071474,0071475,0071476,0071477,0071549,0072350,0097403,0106264,1904628,1904640 P07379 28345895 704 PQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEAVIMRDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM 5v9f A 2.05 BS03 SPV A 1 R87 G236 G237 K243 K244 H264 S286 R405 R85 G234 G235 K241 K242 H262 S284 R403 R87 Y235 K244 H264 S286 C288 D311 R405 R85 Y233 K242 H262 S284 C286 D309 R403 2.7.11.-,4.1.1.32 0000287,0004550,0004611,0004613,0005525,0005737,0005783,0005829,0006006,0006094,0006107,0006629,0009617,0014823,0016301,0016310,0016831,0017076,0018105,0019003,0019543,0030145,0031406,0031667,0032496,0032868,0032869,0033993,0042593,0042594,0043382,0043648,0045944,0046166,0046327,0046872,0046889,0046890,0051365,0070365,0070741,0071300,0071320,0071332,0071333,0071347,0071356,0071377,0071456,0071474,0071475,0071476,0071477,0071549,0072350,0097403,0106264,1904628,1904640 Ki=37uM P07379 28345895 705 PQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEAVIMRDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM