5uqx A 2.23 BS01 8JP A 1 Q297 C300 R301 D305 E308 Y348 D349 H403 Q89 C92 R93 D97 E100 Y140 D141 H195 N218 C223 H464 D481 N10 C15 H256 D273 3.4.19.12 0004843,0016579 Kd=246uM -logKd/Ki=6.21, IC50=0.61uM IC50=1340nM, EC50=2580nM Q93009 29045385 601 KHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQK 5uqx B 2.23 BS01 8JP B 1 Q297 C300 L304 D305 E308 N309 Y348 D349 H403 Q90 C93 L97 D98 E101 N102 Y141 D142 H196 N218 C223 H464 D481 N11 C16 H249 D266 3.4.19.12 0004843,0016579 Kd=246uM IC50=1340nM, EC50=2580nM Q93009 29045385 601 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKR