5uox A 2.5 BS01 8GY A 1 L686 V694 A707 K709 M754 E755 Q756 V757 G759 G760 D807 L810 S821 D822 L17 V25 A38 K40 M85 E86 Q87 V88 G90 G91 D138 L141 S152 D153 D803 K805 D807 N808 D822 T842 D134 K136 D138 N139 D153 T165 2.7.11.25 0004672,0005524,0006468 ic50=5.012nM -logKd/Ki=8.30, IC50=5.01nM EC50=6.3nM, IC50=5.0nM Q99683 28337323 1000 LLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLTFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKV 5uox B 2.5 BS01 8GY B 1 L686 A707 K709 M754 E755 Q756 V757 G760 D807 N808 L810 S821 D822 L17 A38 K40 M81 E82 Q83 V84 G87 D134 N135 L137 S148 D149 D803 K805 D807 N808 D822 T842 D130 K132 D134 N135 D149 T161 2.7.11.25 0004672,0005524,0006468 ic50=5.012nM EC50=6.3nM, IC50=5.0nM Q99683 28337323 1000 LLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLTFTGTLQYMAPEIIYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLK