5u5t A 1.6 BS01 peptide C 0 W103 H104 S105 E107 D109 Y154 S159 P161 P177 R201 L246 L247 L315 G316 D317 L318 F372 W373 Q374 R420 W25 H26 S27 E29 D31 Y76 S81 P83 P99 R123 L168 L169 L229 G230 D231 L232 F286 W287 Q288 R328 ? O75530 27992714 43 ~ 68 KYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVECTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5u5t A 1.6 BS02 7W7 A 1 F97 Y148 N194 D310 Y365 R367 F19 Y70 N116 D224 Y279 R281 ? ic50=3.9uM -logKd/Ki=5.41, IC50=3.9uM IC50=1600nM O75530 27992714 501 KYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVECTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5u5t B 1.6 BS01 peptide D 0 W103 H104 S105 E107 Y154 S159 P161 P177 R201 L246 L315 G316 D317 L318 L353 F372 W373 Q374 L391 E392 V393 R420 W24 H25 S26 E28 Y75 S80 P82 P98 R122 L167 L230 G231 D232 L233 L268 F287 W288 Q289 L306 E307 V308 R328 ? O75530 27992714 41 ~ 68 YSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5u5t B 1.6 BS02 7W7 B 1 F97 Y148 N194 D310 Y365 R367 F18 Y69 N115 D225 Y280 R282 ? ic50=3.9uM IC50=1600nM O75530 27992714 503 YSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL