5trg a 2.804 BS01 7HJ a 1 S20 T21 Q22 S27 V31 K33 I45 G47 A49 S20 T21 Q22 S27 V31 K33 I45 G47 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg b 2.804 BS01 7HJ a 1 D124 A126 G128 W129 D124 A126 G128 W129 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg b 2.804 BS02 7HJ b 1 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg H 2.804 BS01 7HJ H 1 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 3.4.25.1 0004298,0005839,0010498,0051603 -logKd/Ki=7.82, IC50=0.015uM P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg H 2.804 BS02 7HJ N 1 D124 G128 W129 D124 G128 W129 3.4.25.1 0004298,0005839,0010498,0051603 -logKd/Ki=7.82, IC50=0.015uM P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg I 2.804 BS01 7HJ H 1 L91 M95 D124 A125 A126 G128 W129 L91 M95 D124 A125 A126 G128 W129 3.4.25.1 0004298,0005839,0010498,0051603 -logKd/Ki=7.82, IC50=0.015uM P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg I 2.804 BS02 7HJ I 1 S20 T21 Q22 S27 V31 K33 I45 A49 A52 S20 T21 Q22 S27 V31 K33 I45 A49 A52 3.4.25.1 0004298,0005839,0010498,0051603 -logKd/Ki=7.82, IC50=0.015uM P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg J 2.804 BS01 7HJ J 1 T1 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 T1 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg K 2.804 BS01 7HJ J 1 F123 D124 W129 F123 D124 W129 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg K 2.804 BS02 7HJ K 1 S20 T21 Q22 S27 V31 K33 I45 T48 A49 S20 T21 Q22 S27 V31 K33 I45 T48 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg L 2.804 BS01 7HJ K 1 F123 D124 A126 G128 W129 F123 D124 A126 G128 W129 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg L 2.804 BS02 7HJ L 1 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg M 2.804 BS01 7HJ L 1 M95 S122 F123 D124 W129 M95 S122 F123 D124 W129 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg M 2.804 BS02 7HJ M 1 S20 T21 Q22 S27 V31 K33 I45 G47 A49 S20 T21 Q22 S27 V31 K33 I45 G47 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg N 2.804 BS01 7HJ M 1 D124 G128 D124 G128 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg N 2.804 BS02 7HJ N 1 S20 T21 Q22 S27 V31 K33 I45 G47 A49 S20 T21 Q22 S27 V31 K33 I45 G47 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg V 2.804 BS01 7HJ V 1 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg V 2.804 BS02 7HJ b 1 D124 A126 G128 W129 D124 A126 G128 W129 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg W 2.804 BS01 7HJ V 1 D124 G128 W129 D124 G128 W129 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg W 2.804 BS02 7HJ W 1 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 A52 S20 T21 Q22 S27 V31 K33 I45 G47 T48 A49 A52 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg X 2.804 BS01 7HJ W 1 M95 S122 D124 W129 M95 S122 D124 W129 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg X 2.804 BS02 7HJ X 1 S20 T21 Q22 S27 V31 K33 I45 G47 A49 S20 T21 Q22 S27 V31 K33 I45 G47 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg Y 2.804 BS01 7HJ X 1 L91 D124 G128 W129 L91 D124 G128 W129 3.4.25.1 0004298,0005839,0010498,0051603 -logKd/Ki=7.82, IC50=0.015uM P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg Y 2.804 BS02 7HJ Y 1 S20 T21 Q22 S27 V31 K33 I45 G47 A49 S20 T21 Q22 S27 V31 K33 I45 G47 A49 3.4.25.1 0004298,0005839,0010498,0051603 -logKd/Ki=7.82, IC50=0.015uM P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSG 5trg Z 2.804 BS01 7HJ Y 1 D124 G128 W129 D124 G128 W129 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 5trg Z 2.804 BS02 7HJ Z 1 S20 T21 Q22 S27 V31 K33 I45 G47 A49 S20 T21 Q22 S27 V31 K33 I45 G47 A49 3.4.25.1 0004298,0005839,0010498,0051603 P9WHT9 27976853 301 TTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS