5t68 A 2.93 BS01 77V A 1 L377 A400 M450 A451 L453 G454 L501 L15 A38 M83 A84 L86 G87 L134 D494 A496 R498 N499 D512 K533 D127 A129 R131 N132 D145 K162 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=7.64, IC50=0.023uM IC50=23nM, EC50=34nM P43405 27789138 701 VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNEG 5t68 B 2.93 BS01 77V B 1 L377 A400 V433 M448 M450 A451 L453 G454 L501 L15 A38 V66 M81 M83 A84 L86 G87 L134 D494 A496 R498 N499 D512 K533 D127 A129 R131 N132 D145 K162 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=7.64, IC50=0.023uM IC50=23nM, EC50=34nM P43405 27789138 701 VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN