5owc A 1.75 BS01 CA A 1 F26 G28 G30 D47 F26 G28 G30 D47 F26 G28 G30 H46 D47 Y50 Y65 D91 F26 G28 G30 H46 D47 Y50 Y65 D91 3.1.1.4 0001516,0001669,0002532,0003847,0004620,0004623,0005509,0005515,0005543,0005576,0005615,0005764,0006629,0006644,0006658,0007411,0009566,0010744,0010884,0016042,0016787,0019369,0031069,0031410,0032308,0034374,0034638,0036335,0042116,0042632,0043030,0043249,0043433,0046337,0046470,0046471,0046473,0046872,0047498,0050482,0050728,0051247,0051607,0051977,0062234,0090238,0090370,1900016,1990830,2000344 O15496 30034585 201 GILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKC 5owc A 1.75 BS02 AYZ A 1 L5 P17 Y20 G28 L29 G30 C43 H46 D47 L5 P17 Y20 G28 L29 G30 C43 H46 D47 F26 G28 G30 H46 D47 Y50 Y65 D91 F26 G28 G30 H46 D47 Y50 Y65 D91 3.1.1.4 0001516,0001669,0002532,0003847,0004620,0004623,0005509,0005515,0005543,0005576,0005615,0005764,0006629,0006644,0006658,0007411,0009566,0010744,0010884,0016042,0016787,0019369,0031069,0031410,0032308,0034374,0034638,0036335,0042116,0042632,0043030,0043249,0043433,0046337,0046470,0046471,0046473,0046872,0047498,0050482,0050728,0051247,0051607,0051977,0062234,0090238,0090370,1900016,1990830,2000344 ic50=0.026uM -logKd/Ki=7.59, IC50=0.026uM IC50=26nM O15496 30034585 202 GILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKC 5owc B 1.75 BS01 CA B 1 F26 G28 G30 D47 F26 G28 G30 D47 F26 G28 G30 H46 D47 Y50 Y65 D91 F26 G28 G30 H46 D47 Y50 Y65 D91 3.1.1.4 0001516,0001669,0002532,0003847,0004620,0004623,0005509,0005515,0005543,0005576,0005615,0005764,0006629,0006644,0006658,0007411,0009566,0010744,0010884,0016042,0016787,0019369,0031069,0031410,0032308,0034374,0034638,0036335,0042116,0042632,0043030,0043249,0043433,0046337,0046470,0046471,0046473,0046872,0047498,0050482,0050728,0051247,0051607,0051977,0062234,0090238,0090370,1900016,1990830,2000344 O15496 30034585 201 GILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKC 5owc B 1.75 BS02 AYZ B 1 L5 P17 G28 L29 G30 C43 H46 D47 L5 P17 G28 L29 G30 C43 H46 D47 F26 G28 G30 H46 D47 Y50 Y65 D91 F26 G28 G30 H46 D47 Y50 Y65 D91 3.1.1.4 0001516,0001669,0002532,0003847,0004620,0004623,0005509,0005515,0005543,0005576,0005615,0005764,0006629,0006644,0006658,0007411,0009566,0010744,0010884,0016042,0016787,0019369,0031069,0031410,0032308,0034374,0034638,0036335,0042116,0042632,0043030,0043249,0043433,0046337,0046470,0046471,0046473,0046872,0047498,0050482,0050728,0051247,0051607,0051977,0062234,0090238,0090370,1900016,1990830,2000344 ic50=0.026uM IC50=26nM O15496 30034585 202 GILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKC