5otz A 1.46 BS01 TFA A 1 K68 F113 D175 K66 F111 D173 D156 K158 N161 D175 S194 D154 K156 N159 D173 S192 2.7.11.1 0004672,0004674,0005524,0006468 P68400 29732088 403 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5otz A 1.46 BS02 AUT A 1 F121 L124 Y125 P159 V162 I164 M221 M225 F119 L122 Y123 P157 V160 I162 M219 M223 D156 K158 N161 D175 S194 D154 K156 N159 D173 S192 2.7.11.1 0004672,0004674,0005524,0006468 Kd=6.5uM -logKd/Ki=5.19, Kd=6.5uM P68400 29732088 404 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK